Recent content by gracepixie

There might be a marketing issue for this device. Many of us with tinnitus and residual or normal hearing have been told we are not eligible for cochlear implants, so some people who could participate in the clinical trial might not even be considering it. No, this device does not go into the...

2028 is shaping up to be a good year for tinnitus. Cilcare results are expected, Neuralink may become available, Cochlear is expanding their tinnitus implant to a pivotal trial, and the SSD is finally being released. My crystal ball says to bet big on 2028!

Cochlear is currently recruiting for a clinical trial of a device that aims to quiet tinnitus via electrical stimulation of the cochlea via the mastoid bone. You can find more info here. Another thing that makes me excited about this trial is that they have a very robust screening method to...

Wow, @Jammer, I just want to say thank you for your service to the tinnitus community. Your experience with this clinical trial is an example to all of us of the importance of research and the risks involved. I’m deeply grateful that you took that chance for the sake of advancing scientific...

Just to emphasize this, I was in a seminar today where one of my colleagues presented unfavorable data for a new vaccine candidate he was testing. It was heartbreaking. The results in mice and non-human primates were spotless and very encouraging, yet the vaccine didn’t show even a measurable...

@Jammer, you’ve probably shared your experience with DBS many times, but since it’s highly relevant to the discussion about Neurosoft, would you mind sharing it again here? Did you receive an implant? Was there any electrical stimulation involved in your procedure? And was your experience...

One big benefit of the Mongolian gerbil study is that it connects the improvement of tinnitus symptoms to synapse repair. Maybe AC102 will not be able to improve chronic tinnitus, but other therapeutics based on nerve repair, such as CIL-001 and NervGen, gain a boost of optimism that their...

This isn’t true. Several studies have demonstrated significant and consistent reductions in tinnitus with DBS, although the sample sizes have been very limited. Neurosoft is planning to launch their phase 2 study for their tinnitus implant next year, based on positive phase 1 data in a cohort of...

lol, @Furetto and @Joeseph Stope, sorry for my tart responses. My PhD research is in vaccine design, so I’m very familiar with that field and loosely familiar with biotech in general. Joeseph, some people doubt that intratympanic (IT) injections will result in effective drugs for hearing loss...

Sounds like you’re a great candidate for Cilcare’s upcoming clinical trial! Lucky you. They are recruiting people with tinnitus and no hearing loss, with preference given to reactive tinnitus. I believe the trial will start in a few months. Since you’re new, that might feel like a long time, but...

No, the improvement was noticeable within 30 days. However, the article does not specify how much time passed between the blast injury and the first injection. Obviously, that implies the dose was given within 30 days, but it almost certainly began sooner. If I were to guess, I would say it was...

Phase 1 trials are only for first-in-human drugs, designed to test safety. Repurposed drugs that have already been FDA-approved for one condition can move directly to Phase 2 trials, which focus on efficacy for a different condition.

From their website: It was given as subcutaneous daily injections, but the press release doesn’t mention when treatment was started or how long it lasted. Their ongoing clinical trial for Spinal Cord Injury includes two cohorts: A) injury occurring more than one year but no later than ten years...

I have three kids and a job. My tinnitus drives me nuts, but I also have responsibilities, as most of us do. If they have that much money, they should open additional trial sites. Providing equitable access is the responsibility of the drug developer, not the patient.

What company are you with?