Recent content by gracepixie

lol, @Furetto and @Joeseph Stope, sorry for my tart responses. My PhD research is in vaccine design, so I’m very familiar with that field and loosely familiar with biotech in general. Joeseph, some people doubt that intratympanic (IT) injections will result in effective drugs for hearing loss...

Sounds like you’re a great candidate for Cilcare’s upcoming clinical trial! Lucky you. They are recruiting people with tinnitus and no hearing loss, with preference given to reactive tinnitus. I believe the trial will start in a few months. Since you’re new, that might feel like a long time, but...

No, the improvement was noticeable within 30 days. However, the article does not specify how much time passed between the blast injury and the first injection. Obviously, that implies the dose was given within 30 days, but it almost certainly began sooner. If I were to guess, I would say it was...

Phase 1 trials are only for first-in-human drugs, designed to test safety. Repurposed drugs that have already been FDA-approved for one condition can move directly to Phase 2 trials, which focus on efficacy for a different condition.

From their website: It was given as subcutaneous daily injections, but the press release doesn’t mention when treatment was started or how long it lasted. Their ongoing clinical trial for Spinal Cord Injury includes two cohorts: A) injury occurring more than one year but no later than ten years...

I have three kids and a job. My tinnitus drives me nuts, but I also have responsibilities, as most of us do. If they have that much money, they should open additional trial sites. Providing equitable access is the responsibility of the drug developer, not the patient.

What company are you with?

Thanks for keeping us updated, @ErikaS! I'm glad you found a medical team that is willing to work with you!

Hey @ErikaS, What region are you in, and where is this amazing doctor you found?

Yes, I haven’t used Lenire in months, but I still feel my brain shift my tinnitus into the background when I start focusing on something else. It’s still just as loud during quiet moments, though. That said, I went to a conference this week, and my tinnitus wasn’t on my mind nearly as much as...

Hey Erica, I am about to start a clinical trial for Ubrelvy related to my menstrual migraines. I’m curious what effect it might have on my tinnitus. Can you tell me more about your experience with it? Thank you!

For what it’s worth, I signed up for more information about this trial and was promptly contacted by someone from the team to check if I qualified. At first, I thought it was only for veterans, but civilians are eligible as well. Unfortunately, I cannot participate because I am unable to travel...

I’ll take the unpopular side of advocating for Lenire. It didn’t make my tinnitus quieter, but it has helped my mind deprioritize it. Before Lenire, it seemed like my tinnitus would get louder whenever I concentrated, had a conversation, or became interested in something. Shortly after starting...

I cannot remember where I read this, but I heard that Spiral Therapeutics, a Bay Area company focused on drug delivery to the inner ear, had been buying up all the patents for the failed Frequency Therapeutics and Otonomy drugs. I have not been able to find that information again, so it may have...

Hey everyone, I had a PLF from SCUBA diving about six months ago and have had very bad tinnitus ever since. I am making my own spike-timed TENS unit based on Shore’s design to see if it helps. My tinnitus is somatic, but it also includes some beeping and high-pitched tones that are not somatic...