Does Aspirin Have a Protective Role Against Chemotherapeutically Induced Ototoxicity?

To investigate whether aspirin attenuates the ototoxic properties of cisplatin.

  1. Tinnitus Talk
    Aspirin (ASA) has been shown, in an animal model, to attenuate the ototoxic properties of cisplatin. The researchers plan to investigate this in patients undergoing cisplatin chemotherapy.

    The researchers hypothesise that low-dose aspirin can prevent cisplatin induced ototoxicity in the clinical setting.

    Estimated Enrollment: 110
    Study Start Date: February 2008
    Estimated Study Completion Date: February 2010