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Any Drugs That Act as Cortisol Antagonists?

Gl0w0ut

Member
Author
Sep 10, 2017
412
Tinnitus Since
April 2017
Cause of Tinnitus
Unknown
Cortisol is a steroid released by the brain in response to stress, thus it is dubbed the "stress hormone". Obviously, stress stemming from cortisol release seeks to make tinnitus louder. Tinnitus stresses you which elevates cortisol levels. Continuous stress is bad in the long term and, from what I've been told, can lead to issues like heart problems as well a s shrinking of the hippocampus.

The brain is never your friend in the case of tinnitus so doing things to promote its health in neural restoration seems silly. Someone recommended exercise to increase neuroplasticity. A silly suggestion since the excitation of exercise only serves to make tinnitus louder as well as the fact that plasticity created tinnitus to begin with. My goal is to hurt the brain's ability to compensate for acoustical loss/trauma, not help it. My hope is one day we can be able to fire a gun right next to the near, kill hundreds of cilia, but deny the brain the ability to change the auditory cortex and thus stopping tinnitus.

So my question here is what drugs are there that an antagonize cortisol. My brain feels its critical to keep me alert and on my toes so I can quickly resolve problems it dislikes and be alert for danger. I want to suppress this stress so I am calm and inattentive. The brain remains distressed but is deprived of the ability to do anything.
 
Regular exercise and meditation (or, if you're lazy, yoga which combines both) are well documented to reduce cortisol levels. Are you already doing those things?
https://www.health.harvard.edu/staying-healthy/exercising-to-relax
https://www.ncbi.nlm.nih.gov/pubmed/29019089
https://www.ncbi.nlm.nih.gov/pubmed/28963884

Drugs which just straight up quiet the HP axis are fine in acute cases, but longterm use is counterproductive because the body's response is to attempt to restore homeostasis... which means dumping ever more stress hormones into your blood.

You seem to be very actively hostile towards your body and brain. This is literally amping up your cortisol levels. As long as you keep working against yourself and seeing your body and mind as the enemy, you're just going to spiral more.

Gl0w0ut said:
A silly suggestion since the excitation of exercise only serves to make tinnitus louder as well as the fact that plasticity created tinnitus to begin with.
You're just wrong about this, the neurological, physiological and psychological models do not agree with you and neither does the data.
https://www.ncbi.nlm.nih.gov/pubmed/23930543

By all means, avoid exercise and bombard your body with drugs; you're the only one who's going to suffer more as a result.
 
Regular exercise and meditation (or, if you're lazy, yoga which combines both) are well documented to reduce cortisol levels. Are you already doing those things?
https://www.health.harvard.edu/staying-healthy/exercising-to-relax
https://www.ncbi.nlm.nih.gov/pubmed/29019089
https://www.ncbi.nlm.nih.gov/pubmed/28963884

Drugs which just straight up quiet the HP axis are fine in acute cases, but longterm use is counterproductive because the body's response is to attempt to restore homeostasis... which means dumping ever more stress hormones into your blood.

You seem to be very actively hostile towards your body and brain. This is literally amping up your cortisol levels. As long as you keep working against yourself and seeing your body and mind as the enemy, you're just going to spiral more.


You're just wrong about this, the neurological, physiological and psychological models do not agree with you and neither does the data.
https://www.ncbi.nlm.nih.gov/pubmed/23930543

By all means, avoid exercise and bombard your body with drugs; you're the only one who's going to suffer more as a result.
Let's see it try and restore balance. I will amp up the dose so it's tolerance building fails to offset it. I will continue to antagonize the brain in any way I can. Helping it will not make things better. It's already broken. All I can do now is make it suffer for what it's done to me. Mess with it's chemistry and defense mechanisms.
 
Regular exercise and meditation (or, if you're lazy, yoga which combines both) are well documented to reduce cortisol levels. Are you already doing those things?
https://www.health.harvard.edu/staying-healthy/exercising-to-relax
https://www.ncbi.nlm.nih.gov/pubmed/29019089
https://www.ncbi.nlm.nih.gov/pubmed/28963884

Drugs which just straight up quiet the HP axis are fine in acute cases, but longterm use is counterproductive because the body's response is to attempt to restore homeostasis... which means dumping ever more stress hormones into your blood.

You seem to be very actively hostile towards your body and brain. This is literally amping up your cortisol levels. As long as you keep working against yourself and seeing your body and mind as the enemy, you're just going to spiral more.


You're just wrong about this, the neurological, physiological and psychological models do not agree with you and neither does the data.
https://www.ncbi.nlm.nih.gov/pubmed/23930543

By all means, avoid exercise and bombard your body with drugs; you're the only one who's going to suffer more as a result.
Also, that study talks more about tinnitus prevention and those with acute tinnitus. It's too late for me now. My brain already went plastic and exercise won't fix it. And wow, a 4% reduction. How impressive.
 
Coincidentally, I just received a cortisol saliva test, which I purchased through the mail, to test my levels which I believe may not be sufficient.

The effects of low cortisol levels are outlined here, and they include Addison's Disease, which I do not believe is a desirable trade-off for supposedly lower T levels:

https://www.livestrong.com/article/24059-effects-low-cortisol-levels/

I think there's better ways to lower Tinnitus Distress than getting yourself sicker.
 
Coincidentally, I just received a cortisol saliva test, which I purchased through the mail, to test my levels which I believe may not be sufficient.

The effects of low cortisol levels are outlined here, and they include Addison's Disease, which I do not believe is a desirable trade-off for supposedly lower T levels:

https://www.livestrong.com/article/24059-effects-low-cortisol-levels/

I think there's better ways to lower Tinnitus Distress than getting yourself sicker.
I already suffer from fatigue and gastro problems. I don't care about loss of reproductions (making me sterile) and I would actually benefit from lower blood pressure. So yes, I need low cortisol levels. A new, low tone has developed in my left ear and it driving me insane. No doubt I now have high cortisol levels.
 
I already suffer from fatigue and gastro problems. I don't care about loss of reproductions (making me sterile) and I would actually benefit from lower blood pressure. So yes, I need low cortisol levels. A new, low tone has developed in my left ear and it driving me insane. No doubt I now have high cortisol levels.
Get a Cortisol level test, and find out, like the one I ordered. It's only about 40 bucks. I only got it today. You take three saliva samples, send it in, they process it and analyze it and send you the results, supposedly written in a way that most people can understand.
 
Get a Cortisol level test, and find out, like the one I ordered. It's only about 40 bucks. I only got it today. You take three saliva samples, send it in, they process it and analyze it and send you the results, supposedly written in a way that most people can understand.
How do I know it actually a lab test and not just some scam that says it is?
 

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