Deep Brain Stimulation (DBS) for Tinnitus
- Thread starter dan
- Start date
MemberHere:
And here is the oral defense of her PhD, which I haven't yet watched with English subtitles:
Six patients were planned, but only four completed the implantation and one-year follow-up.
After one year:
The most important part of the thesis, chapter 7, is still under embargo, as the corresponding paper is under peer review (in Neurotherapeutics).
For now, only the detailed single case of the super-responder has been published.
It's somewhat disappointing in terms of results, although there remains some cautious optimism. DBS can be remarkably effective in desperate cases, far more than any other treatment, but only for a limited and still poorly identified group of patients.
Ideally, researchers need to determine in advance who can truly benefit from it, which will require more studies.
In short, before this procedure becomes available for severe cases, we'll probably have to wait another ten years or so, though I could be wrong.
Let's not forget the other DBS studies, including those in France, which target different areas of the brain. Together, they could lead to a faster and broader understanding of the full potential of DBS.
And here is the oral defense of her PhD, which I haven't yet watched with English subtitles:
Six patients were planned, but only four completed the implantation and one-year follow-up.
After one year:
- 1 patient ("super-responder") showed major improvement
- 2 had mild, non-significant improvements
- 1 had no benefit
The most important part of the thesis, chapter 7, is still under embargo, as the corresponding paper is under peer review (in Neurotherapeutics).
For now, only the detailed single case of the super-responder has been published.
It's somewhat disappointing in terms of results, although there remains some cautious optimism. DBS can be remarkably effective in desperate cases, far more than any other treatment, but only for a limited and still poorly identified group of patients.
Ideally, researchers need to determine in advance who can truly benefit from it, which will require more studies.
In short, before this procedure becomes available for severe cases, we'll probably have to wait another ten years or so, though I could be wrong.
Let's not forget the other DBS studies, including those in France, which target different areas of the brain. Together, they could lead to a faster and broader understanding of the full potential of DBS.
Thank you @lusiol. I posted in another thread about an ultrasound helmet that can have the same effect as DBS. I think using something like that to pinpoint where to permanently stimulate in the future will make a big difference. At the moment, it feels like guessing, but at the same time, it clearly has a strong effect when done correctly.
withintention
Member
- Nov 26, 2023
- 130
- Tinnitus Since
- 10/2023
- Cause of Tinnitus
- Noise and/or infection
From the paper:
That's good news.
It seems we should discount the 4th non-responder, then. So, two out of three had clinically relevant improvements after one year.
That's good news.
delta784
Member
withintention
Member
- Nov 26, 2023
- 130
- Tinnitus Since
- 10/2023
- Cause of Tinnitus
- Noise and/or infection
This article gives a brief summary of the trial as well as the plan to do a clinical trial with 16 patients this time around.
Well well well... 
nltimes.nl
Maastricht UMC+ finds breakthrough in tinnitus treatment with deep brain stimulation
Deep brain stimulation, or DBS, is safe and possibly effective for people with severe tinnitus, according to a new study from Maastricht UMC+ that involved four patients undergoing brain surgery. None of the patients treated with brain stimulation experienced lasting side effects, and three...
nltimes.nl
1 had a significant improvement.Well well well...
Maastricht UMC+ finds breakthrough in tinnitus treatment with deep brain stimulation
Deep brain stimulation, or DBS, is safe and possibly effective for people with severe tinnitus, according to a new study from Maastricht UMC+ that involved four patients undergoing brain surgery. None of the patients treated with brain stimulation experienced lasting side effects, and three...
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