Direct Mapping of the Corticol Tinnitus Network

AnnaW

Member
Author
Benefactor
Oct 3, 2014
72
London
Tinnitus Since
1998
http://myweb.uiowa.edu/pgander/AudCtx 2014 Tinnitus.pdf
Tinnitus occurs when damage to the peripheral auditory system leads to
spontaneous brain activity that is interpreted as sound. Many types of brain
activity show abnormalities in association with tinnitus, but it is not clear
which of these relate to the phantom sound itself, as opposed to
predisposing factors or secondary consequences. Direct demonstration of
the core tinnitus correlates requires high-precision recordings of neural
activity combined with a behavioral paradigm in which the perception of
tinnitus is manipulated and accurately reported upon by the subject. This
has thus far not been possible in animal or human research. Here we
present extensive intracranial recordings from an awake, behaving tinnitus
patient during short-term modifications in perceived tinnitus loudness,
permitting a robust characterization of the core tinnitus brain network.

This looks quite interesting but a little too much for my brain after 9pm at night!
 
Not sure I completely get this. But if changes are shown within the central auditory cortex during residual inhibition, surely this underlines that plastic changes during t suppression are more than just perception, but actual changes within the auditory system.
However, on the other hand, changes also shown in other areas of the brain denoting emotional and response components could add a different story.
 

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