New Study on Trobalt/Maxipost in Relation to SHL-induced Tinnitus

The following very recent finding from an animal model may have implications for Trobalt and its therapeutic potential on the treatment of symptoms of tinnitus. I will try to find out more.

 

Here's the article if you need it

 

from article

"RTG would suppress low-frequency tinnitus, 123
while Maxipost, in contrast, would suppress high frequency 124
tinnitus. Since SS is believed to induce a high pitched tinnitus 125

 

Yeah from the way this is written it sounds like that.

However the take home message is researchers show playing around with K+ channel functions directly affect the auditory system of animals after it is damaged. This shows more promise than anything else really.

 

The reason I posted the information further up was because the animal-study was brought to my attention by the Tinnitus Research Initiative which has submitted a manuscript to the journal "Expert Opinion On Pharmacotherapy" based - in part - on participants who volunteered their experience with Trobalt as pertains to efficacy in relation to treatment of symptoms of tinnitus. The animal-study may help explain why some participants of the informal trial here on TT saw better improvements than others re:

"However when Maxipost or RTG were administered with SS, Maxipost prevented the SS-reduced CAP amplitudes at high frequencies (≥20 kHz) and RTG prevented SS-reduced CAP amplitudes at low frequencies (≤8 kHz)."

The above, therefore, represents a dichotomy in the treatment potential and could be explored further either retrospectively, or going forward with other volunteers.

The reason I posted the article had nothing to do with the basic overall efficacy of Trobalt, but instead because of the specific finding as quoted.

attheedgeofscience
12/MAY/2015.

 

@attheedgeofscience has requested that I post this relevant paper for him.

 

It's good rats get relief from tinnitus!