NMDA Receptor Antagonist Question

Discussion in 'Support' started by bots, Nov 4, 2015.

tinnitus forum
    1. bots

      bots Member

      Tinnitus Since:
      Hi All - first post on the site.

      I recently developed t from a loud concert (about a month ago) and am scheduled to receive AM101 (or placebo) starting next week.

      In my research on AM101 it appears that the side effects are minimal and generally short-term. I've been reading up on NMDA receptors and in addition to receiving the phantom t signal, they are also involved in learning and memory functions.

      My question is this (for the more scientifically informed than myself): are there believed to be any long-term risk to memory, learning (or other functions) associated with AM101 or other NMDA antagonists? The available AM101 literature does not appear to describe any, but the idea of inhibiting a receptor that plays a role in learning/memory has me a bit concerned. I'm hoping that a bit of education on this issue will ease my mind.

      Many thanks!

    2. linearb

      linearb Member Hall of Fame

      East Coast USA
      Tinnitus Since:
      The risks of limited exposure are not very significant. This drug is a ketamine analog; ketamine is considered medically safe for children as a surgical anesthetic. I'd say that the overall risks from a tympanic injection are more significant than the risk from a single exposure to ketamine.

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