Otomagnetics — A New Drug Delivery System for the Inner and Middle Ear

Discussion in 'Research News' started by WickedCarnival, Oct 5, 2018.

  1. Watch Hazel share good news about tinnitus
    1. weab00
      Gloomy

      weab00 Member Benefactor

      Location:
      Joe Dart's basement
      Tinnitus Since:
      05/2019
      Cause of Tinnitus:
      some good mf music
      Free masons were knocked out of power and now we can proceed with curing every ailment in the body, cyborgs, and spatial/oceanic colonization. Once we're done curing ourselves, we can cure the universe.
       
      • Like Like x 2
    2. Tau
      Probing

      Tau Member

      Location:
      Europe
      Tinnitus Since:
      2019
      Cause of Tinnitus:
      2019-Concert, 2021-headphones/acoustic trauma at 110dB,16kHz
      I see a few issues with this approach.

      First, the magnetic NPs, even though they claim they are biodegradable, may be toxic. I have worked with nanoparticles (and even magnetic NPs), and you don't want them inside you most of the time. I wonder how they made the magnetic ones biodegradable, if they likely contain iron oxide.

      Second, this will require an intratympanic injection anyway. So I would like to see a comparison with a slow release gel (Otonomy and Frequency Therapeutics approaches).
       
      • Good Question Good Question x 1
      • Informative Informative x 1
    3. Gb3

      Gb3 Member

      Tinnitus Since:
      12/19
      Cause of Tinnitus:
      Sshl
      How will it require an injection anyway? The whole point of this is that it can penetrate the ear drum and round window without an injection.
       
    4. Tau
      Probing

      Tau Member

      Location:
      Europe
      Tinnitus Since:
      2019
      Cause of Tinnitus:
      2019-Concert, 2021-headphones/acoustic trauma at 110dB,16kHz
      You need the fluid with the MNPs inside your middle ear for the particles to diffuse along a B field gradient.

      Edit: If you have no liquid in your middle ear, the particles which had just been transported through the tympanic membrane will simply get stuck to any wet surface and that's it really.
       
      • Good Question Good Question x 1
      • Funny Funny x 1
Loading...

Share This Page