Sulpiride Plus Hydroxyzine Decrease Tinnitus Perception

Discussion in 'Research News' started by Danny Boy, Jul 9, 2015.

    1. Benoves

      Benoves Member Benefactor

      Tinnitus Since:
      26-9-2017
      Cause of Tinnitus:
      Unknow possibly noise trauma
      Think I might try. Nothing to lose
       
      • Like Like x 3
    2. Codaz

      Codaz Member

      Sulpiride is mentioned in my "Living with Menieres decease" book from 1996 as anti vertigo drug. Brand name Dogmatil.
       
    3. undecided
      Breezy

      undecided Member

      Location:
      Greece
      Tinnitus Since:
      04/2014
      Cause of Tinnitus:
      Unknown.
      Cause it won't work, just like any other promising research drug combo.
      What we need is a specific t drug, not some random combinations that might make sense in a researcher's head.
       
      • Agree Agree x 1
      • Funny Funny x 1
    4. Codaz

      Codaz Member

      I first have to check the negative side effects.
       
      • Agree Agree x 1
    5. Fatih
      Disapproved

      Fatih Member

      Tinnitus Since:
      March 2017
      Cause of Tinnitus:
      Tympanoplasty
      maybe i'll try them
      ANJIOFLUX 250 LRU
      SULPIR 50 MG 30
       
    6. Lost life
      Alone

      Lost life Member

      Location:
      san francisco california
      Tinnitus Since:
      3-17
      Cause of Tinnitus:
      benzo w/d noise/trauma ,stress,tmj,hearing loss
      i take hydoxyzine and it helps just a little bit
       
    7. David077
      Creative

      David077 Member

      Tinnitus Since:
      2013
      Cause of Tinnitus:
      stress, benzo/clonozepam + clonidine, maybe infection
      Sulpiride strengthens sedating effect of the sedating drugs that coming in combination with it. Following that, I think we have to learn how Hydroxyzine affects the sedative effect on the brain and how it affected by the Sulpiride.
       
      • Informative Informative x 1
    8. ma7555
      Doubtful

      ma7555 Member

      Tinnitus Since:
      04/2022
      Cause of Tinnitus:
      Bupropion
      I am currently experimenting with Sulpiride (50 mg every 12 hours) + Melatonin (3 mg every 24 hours). I have a Hydroxyzine box waiting too but I am not sure if I will add that to the cocktail. Still on day 2.
       
      • Informative Informative x 1
    9. ma7555
      Doubtful

      ma7555 Member

      Tinnitus Since:
      04/2022
      Cause of Tinnitus:
      Bupropion
      I added 15 mg Hydroxyzine every 12 hours too. I currently take the full stack but on a lower dosage Sulpiride (100 mg) + Hydroxyzine (30 mg) + Melatonin (3 mg). I will titrate the Hydroxyzine to 50 mg over the next few days but will keep the Sulpiride at 100 mg.

      To be honest, I feel it is detrimental in my case but it has only been a week and I don't want to quit so early. If @Inge is still around, can you tell me when did you start seeing improvements?

      On the other hand, I have so far experienced no side effects.
       
      • Informative Informative x 1
    10. Ela Stefan

      Ela Stefan Member

      Tinnitus Since:
      11/2018
      Cause of Tinnitus:
      Ear Infection
      How is it going with your treatment?
       
      • Good Question Good Question x 1
    11. Tomas80

      Tomas80 Member Benefactor

      Tinnitus Since:
      10/2018
      Cause of Tinnitus:
      Unknow. Maybe stress?
      i tried this combination (Sulpiride + Hydroxyzine) for several weeks and it didn't help at all.
       
      • Informative Informative x 2
    12. ma7555
      Doubtful

      ma7555 Member

      Tinnitus Since:
      04/2022
      Cause of Tinnitus:
      Bupropion
      I stopped after trying for a month. The tinnitus got louder first, then returned to base level in week 2. It made me much better for sure psychologically by week 3 and I did not care about the tinnitus as much but the tinnitus loudness stayed around the same so it was not worth the risk. I did not get any side effects while taking this but I encountered some mild restlessness on the few days after stopping which rapidly vanished.

      So for me, it did not work as I expected.
       
      • Hug Hug x 3
      • Informative Informative x 1
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