Supplements & Tinnitus — What Do You Take? What Should I Take?

Discussion in 'Treatments' started by oatsey, Mar 25, 2013.

    1. Rube
      Fine

      Rube Member Benefactor

      Location:
      USA
      Tinnitus Since:
      7/2014
      Cause of Tinnitus:
      Loud shit
    2. Carlos1

      Carlos1 Member Benefactor

      Location:
      Boston
      Tinnitus Since:
      08/2013
      Cause of Tinnitus:
      Root Canal
       
    3. Rube
      Fine

      Rube Member Benefactor

      Location:
      USA
      Tinnitus Since:
      7/2014
      Cause of Tinnitus:
      Loud shit
      @Carlos1 no I haven't tried it. I don't even know how I would be able to get it....looks like a prescription medication. I never looked into it beyond reading those articles.
       
    4. ruben ruiz

      ruben ruiz Member

      Location:
      Tucson, AZ
      Tinnitus Since:
      2012
      Cause of Tinnitus:
      I believe it was meds and stress
      Has anyone tried sulodexide? It looks promising. Its an older med used for neuropythy.
      Tinnitus is considered as a secondary neuropythy.
       
    5. I just bought some Niacin but they are only 50 mg tablets...lol..
       
    6. Karen
      Talkative

      Karen Manager Staff Benefactor Ambassador Hall of Fame

      Location:
      U.S.
      Tinnitus Since:
      05/2010
      Cause of Tinnitus:
      First time: Noise 2nd Time: Ototoxic drug
      Hi, @Street Spirit,

      I'll be interested to hear how the niacin works for you. And if that doesn't work, you might then want to try NAC (N-acetylcistene). That's another supplement I've been taking recently, and it does seem to take the worst of the edge off my tinnitus. Both supplements are worth a try. Give the niacin a couple weeks to really start working.

      Good luck!
       
    7. Thanks Karen! Yea NAC I keep meaning to get that lol. Will keep TT updated. .hey you never know! :)
       
    8. Oh my I am such an idiot. It is 500 mg and I am experiencing intense flushing. My ears are on fire right now. I am pounding back the water!
       
    9. ruben ruiz

      ruben ruiz Member

      Location:
      Tucson, AZ
      Tinnitus Since:
      2012
      Cause of Tinnitus:
      I believe it was meds and stress
      Zinc, niacin, Omega 3, vitamin c and e, alpha lipoic acid...
      dont over protect your ears, just use plugs when its obvious.
       
      • Like Like x 1
    10. Rube
      Fine

      Rube Member Benefactor

      Location:
      USA
      Tinnitus Since:
      7/2014
      Cause of Tinnitus:
      Loud shit
      You should be fine, the flush is only temporary. I think eating something will help.
       
      • Like Like x 1
    11. Just drinking water. It's calming down but have to say that it was quite intense! burning, itching, craziness! I will continue but start at a smaller dose and work my way up..lol
       
    12. Rube
      Fine

      Rube Member Benefactor

      Location:
      USA
      Tinnitus Since:
      7/2014
      Cause of Tinnitus:
      Loud shit
      Did it have any affects on ur t or h?
       
    13. Well I didn't notice anything for several hours and then my T spiked but I doubt it was from that as my tmj was bad and it was also 2am. Seriously though. That flushing is really something else. lol
       
    14. jimH
      No Mood

      jimH Member Benefactor

      Tinnitus Since:
      30 years+
      Cause of Tinnitus:
      Acoustic trauma
      There are a number of brands of "No Flush Niacin" available if the flushing continues to be a problem for you. I know the feeling because I've experienced it myself.

      http://www.swansonvitamins.com/q?kw=no+flush+niacin
       
    15. Oh, well then.. Thanks Jim! I must try them instead...the burning and itching lasted alot longer than I would like and strangely, in my left ear, the same side I have alot of tmj issues.. I did read how some folks work their way up to 500mg..but a no flush would be awesome as I wasn't expecting quite that.
       
    16. Atlantis

      Atlantis Member

      Tinnitus Since:
      02/2014
      Is the No Flush Niacin version as effective as the regular version that gives the flush?
       
      • Good Question Good Question x 1
    17. jimH
      No Mood

      jimH Member Benefactor

      Tinnitus Since:
      30 years+
      Cause of Tinnitus:
      Acoustic trauma
    18. MontmorencyTT

      MontmorencyTT Member

      Location:
      Abingdon, Oxfordshire
      Tinnitus Since:
      1/1990 (very approx)
      Cause of Tinnitus:
      Probably ear infection. (Also led to HF hearing loss)
      Where are your sources for that?

      I'd recommend anyone wanting to know more about vitamin B3 to read the books by the late Dr Abram Hoffer, who was a respected pioneer in its use.

      While it goes by the general name of Niacin, it comes in 3 main forms:
      1. Nicotinic acid - this is the one that causes flushing, and the one that Hoffer recommended in most cases, if the person can tolerate the flushing (which you get used to, usually, and the effect often wears off after continual use. It's also the cheapest form.

      2. Nicotinamide

      3. Inositol Hexanicotinate

      Neither 2. nor 3. produce a flush. Apart from that, they mostly have the same clinical effects, except that Hoffer thought 1. was the most effective in most cases.

      From memory, I _think_ it's only 2. - Nicotinamide - that might pose some risks with continued use at high doses.

      I take nicotinic acid daily, for lots of reasons actually, and not particularly because of T.
      I do not believe it's dangerous for the liver, but of course, I would advise anyone else to do their own research.
       
    19. MontmorencyTT

      MontmorencyTT Member

      Location:
      Abingdon, Oxfordshire
      Tinnitus Since:
      1/1990 (very approx)
      Cause of Tinnitus:
      Probably ear infection. (Also led to HF hearing loss)
      That's definitely a good idea,. but once you have been taking it over a long period, the effect probably won't even be there any more, or at least, will hardly be noticable.

      ...

      While I am posting, I'll mention that I take a wide range of vitamin and some mineral supplements, for a variety of reasons, and not specifically for tinnitus, including most of the ones mentioned in this thread (although not Gingko).

      Of course, it would be best to get everything from our diet, but that's usually not possible, sad to say.
      I do prefer to get my vitamin A from food sources (e.g. unpasteurised butter and occasional lamb's liver), and vitamin K2 from cheese and also from liver.

      ...

      And please don't take the following as a recommendation, but just a thought for those who don't mind doing some searching and reading up: Something that I don't think has been mentioned so far: iodine.
      (e.g. Lugol's solution).

      Now I suspect most GPs and a lot of specialists will say that iodine supplements are unnecessary and possibly dangerous. I'm not going to get into a discussion about that, but merely suggest checking out the work of people like:
      Mark Sircus
      David Brownstein
      Jorge D. Flechas
      Guy. E. Abraham

      As with, say, niacin and vitamin C, there are lots of reasons to suspect that iodine supplementation may be helpful for a lot of reasons. Whether it is directly applicable to tinnitus or not is a moot point, although I can think of one possible application: allergies. I have read a very interesting thread on this forum in which one person definitely, and another possibly, had tinnitus directly related to inflamed Eustachian tubes, probably caused by allergies. Now, it seems that iodine insufficiency may be related to increased chances of suffering from allergies. When iodine is mentioned we tend to think of the thyroid gland, but it turns out that only about 3% of the body's iodine is stored in the thyroid gland, and the rest spread out over other body tissues, including the skin (lack of iodine can stop you sweating, for example). The obvious inference is that iodine insufficiency (just like magnesium insufficiency to take another example) could lead to a whole host of problems, simply because it is involved in so many different components of the body.

      Just to repeat: please don't take any of the above as a recommendation, but simply as food for thought.
       
      • Like Like x 1
    20. Yea was just doing some reading regarding niacin and didn't realize there is a possibility, though uncommon, of liver toxicity in regular high doses, apparently more common in extended release form. I have to admit this is the first time I've taken anything without proper research :/

      "Niacin in doses above 500 mg daily causes transient, asymptomatic elevations in serum aminotransferase levels in up to 20% of people. The elevations are rarely greater than 3 times the upper limit of the normal range and usually resolve spontaneously even with continuation of the drug. The effect is partially dose related and is more common with doses above 3 g/day. In some patients, there is an overall decrease in serum proteins synthesized by the liver and, in some instances, coagulopathy with an increase in prothrombin time and decline in serum albumin, coagulation factors and apolipoproteins. These changes resolve rapidly upon stopping therapy and may not recur with lower doses. Niacin can also cause serious hepatotoxicity, but this is uncommon. Significant hepatotoxicity is particularly common with high doses of sustained release niacin. In many cases, the injury becomes apparent after a dose increase or after switching from the regular crystalline to a sustained release form. The pattern is primarily hepatocellular, although cases with a cholestatic pattern have been described. The patients present with jaundice, itching, nausea, vomiting and fatigue. When the injury is the result of switching from the crystalline to the sustained release form, the injury may present acutely within days or a few weeks with a prodromal period of nausea, vomiting and abdominal pain, that is followed by jaundice and pruritus. Early during the injury serum aminotransferase levels are very high and then usually fall rapidly with discontinuation or dose lowering. The clinical phenotype resembles acute hepatic necrosis, suggesting a direct toxic effect. Imaging studies of the liver may reveal areas of hypodensity ("starry sky liver") interpreted as focal fatty infiltration that resolves after stopping the drug. Liver biopsy typically shows varying degrees of centrolobular necrosis with only mild inflammation.

      Mechanism of Injury

      The mechanism of hepatotoxicity is assumed to be an intrinsic toxic reaction related to high serum levels of niacin that overwhelm the high affinity, low concentration nicotinic acid receptors (that are responsible for the flushing response). The finding that niacin can be restarted at lower doses after an episode of clinically apparent injury indicates that the hepatic damage is unlikely to be idiosyncratic or due to hypersensitivity.

      Outcome and Management

      Niacin hepatotoxicity appears to be dose dependent and more common with the sustained release form of the drug. Hepatotoxicity is less common with regular, crystalline niacin or extended release niacin. Most cases are mild and resolve rapidly upon stopping the medication, although in some instances, the injury is acute and severe and progresses to liver failure that is fatal or requires emergency liver transplantation. Complete resolution of the clinical symptoms is expected within days of stopping niacin, whereas serum enzyme elevations may require several weeks or months to resolve. Rechallenge with the same form leads to rapid recurrence and should be avoided. If the injury occurred after switching to a SR formulation, the crystalline form of niacin may be restarted at a lower dose and with caution."

      http://livertox.nih.gov/Niacin.htm
       
    21. dan26
      Frustrated

      dan26 Member

      Location:
      NJ
      Tinnitus Since:
      1981
      Cause of Tinnitus:
      complete loss of hearing. motorcycle accident
      I read this now and i am going to see what my neurotologist says about trying something like this. Hopefully i can try it and see what happens instead of this suffering day in and day out. I have a 10 month old baby boy so ya know I need all the help i can get i trying to get some relief with these crazy noises.
       
    22. Rube
      Fine

      Rube Member Benefactor

      Location:
      USA
      Tinnitus Since:
      7/2014
      Cause of Tinnitus:
      Loud shit
      Please let us know how you make out
       
    23. Danny Boy
      Cheerful

      Danny Boy Member Benefactor Hall of Fame

      Location:
      England
      Tinnitus Since:
      7/2014
      Cause of Tinnitus:
      Ear infection
      Have you had your blood checked for deficiencies?
       
    24. Christian78
      Alone

      Christian78 Member

      Location:
      Gothenburg
      Tinnitus Since:
      (Sep 2013)
      Cause of Tinnitus:
      progressive tinnitus, time of expiring in next 3-6 months
      how can i still your nickname? :)

      i think niacin is not good for tinnitus,

      go to doctor and say you wanna do COMPLETE BLOOD TEST ON electrolytes and immuno tests, and normal blood test on blood counts and normal on plasma and so on so you get around 25 blood results
       
    25. Danny Boy
      Cheerful

      Danny Boy Member Benefactor Hall of Fame

      Location:
      England
      Tinnitus Since:
      7/2014
      Cause of Tinnitus:
      Ear infection
      Sounds prickly.
       
    26. mrdude1234

      mrdude1234 Member

      Hey all, I think I have tinnitus from Epstein Barr. I tested positive for the virus (at acute stage) and my girlfriend also has tinnitus now as I probably passed the virus onto her (which really sucks).

      I have had tinnitus for about a month and she has had for 2 weeks. Anything we can possibly take to possibly reduce or eliminate the T as it's still kinda early and am pretty sure it's virus related.

      Thanks!
       
    27. Nucleo

      Nucleo Member Benefactor

      Tinnitus Since:
      02/2011
      Prednisone or the AM-101 trial are your best bets.
       
    28. mrdude1234

      mrdude1234 Member

      Predisnone even though no hearing loss?
       
    29. Karen
      Talkative

      Karen Manager Staff Benefactor Ambassador Hall of Fame

      Location:
      U.S.
      Tinnitus Since:
      05/2010
      Cause of Tinnitus:
      First time: Noise 2nd Time: Ototoxic drug
      Hi, folks,

      I have my blood tested regularly, and haven't had any problems with the niacin. However, I am taking a break from it right now.

      I'd be interested to hear from others who have tried it, to see if it has affected your tinnitus one way or the other.

      Now that I'm not taking it any more, I'm not sure I can see any difference without it. I am still taking NAC, though, which I believe does seem to help.
       
    30. Nucleo

      Nucleo Member Benefactor

      Tinnitus Since:
      02/2011
      Some doctors prescribe it even though there is no hearing loss. You don't know if you have hearing loss in the 8 khz+ frequencies since not a whole lot of places offer these tests. 12 khz hearing loss can lead to tinnitus all the same. The potential benefits of a short course of emergency prednisone far outweighs the side effects.

      If it doesn't work then AM-101 is pretty much the only pharmaceutical option outside of off-label drugs like retigabine or keppra.
       

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