Tinnitus and Erectile Dysfunction Drugs

Johno · Oct 17, 2014

Hello Friends. I know, this thread is little bit controversial , but in my opinion, it is also important. So... have you, for example, good friend with Tinnitus, who has some experiences with those drugs? I have friend with T and he probably has psychological ED, his tool is not very reliable, cause after acoustic trauma he has not flavour to meet beautiful woman more, because he got strong deppresion. But now, after more than 2 years he will get back his sexual life. He will try some of those drugs, only on beginning... but he is afraid of worsening of T...

Sound Wave · Oct 18, 2014

ED drugs can cause T + hearing loss, so I would stay away from them

yonkapin · Oct 18, 2014

I wouldn't have thought they would be a problem but it apparently might be the case:

http://en.wikipedia.org/wiki/Ototoxicity

Others
Ototoxic effects are also seen with quinine and heavy metals such as mercury and lead.[7] At high doses, aspirin and other salicylates may also cause high-pitch tinnitus and hearing loss in both ears, typically reversible upon discontinuation of the drug.[7] The erectile dysfunction medications Viagra, Levitra, and Cialis have also been reported to cause hearing loss.[14]
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http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/2007/ucm109012.htm

FDA Announces Revisions to Labels for Cialis, Levitra and Viagra
Potential risk of sudden hearing loss with ED drugs to be displayed more prominently
The U.S. Food and Drug Administration has approved labeling changes for erectile dysfunction (ED) drugs in the class that includes Cialis, Levitra, and Viagra, to display more prominently the potential risk of sudden hearing loss, and to guide consumers on what to do if they experience sudden problems with their hearing.

In addition, the FDA plans to require the same changes in labeling for the drug Revatio, also a member of this drug class known as phosphodiesterase type 5 (PDE5) inhibitors. Revatio is used to treat pulmonary arterial hypertension (PAH). PAH is a serious medical condition in which continuous high blood pressure in arteries of the lungs weakens the heart muscle and often leads to right heart failure and death.

The FDA asked manufacturers of these drugs to revise product labeling after a very small number of patients taking the PDE5 inhibitors reported sudden hearing loss, sometimes accompanied by ringing in the ears and dizziness.

"Because some level of hearing loss is usually associated with the aging process, patients on these drugs may not think to talk to their doctor about it," said Janet Woodcock, M.D., FDA's deputy commissioner for scientific and medical programs, chief medical officer, and acting director of its Center for Drug Evaluation and Research.

Patients taking Cialis, Levitra, or Viagra who experience sudden hearing loss should immediately stop taking the drug and seek prompt medical attention. Those using Revatio should continue taking their medication but should contact their health care provider for further evaluation. Because Revatio is used to treat a potentially life-threatening condition, the FDA does not recommend patients abruptly stop taking this medication but should consult their physician if they experience sudden problems with their hearing.

A case report in the April 2007 issue of the Journal of Laryngology & Otology involving sudden hearing loss in a man taking Viagra prompted the FDA to search the FDA's Adverse Events Reporting System for instances of hearing loss and PDE5 inhibitors. The FDA found a total of 29 postmarketing reports of sudden hearing loss, both with and without accompanying ringing in the ears, vertigo, or dizziness. In most of the cases, the hearing loss involved one ear. The hearing loss was either a partial or complete loss of usual hearing. In approximately one third of cases, the event was temporary. In the remainder, the hearing loss was ongoing at the time of the report or the final outcome was not described.

Although no causal relationship has been demonstrated, the strong relationship between the use of these drugs and sudden hearing loss in these cases warrants revisions to the product labeling for this drug class.

Product Web sites, marketing and educational materials, and advertisements for PDE5 inhibitors will reflect the revised product labeling. The label revisions can be viewed at: www.fda.gov/cder/drug/DrugSafety/DrugIndex.htm.
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Telis · Oct 18, 2014

Johno said: ↑

Hello Friends. I know, this thread is little bit controversial , but in my opinion, it is also important. So... have you, for example, good friend with Tinnitus, who has some experiences with those drugs? I have friend with T and he probably has psychological ED, his tool is not very reliable, cause after acoustic trauma he has not flavour to meet beautiful woman more, because he got strong deppresion. But now, after more than 2 years he will get back his sexual life. He will try some of those drugs, only on beginning... but he is afraid of worsening of T...

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I watched a commercial just the other day for Viagra, one of the side effects mentioned was hearing loss. He could be making things a whole lot worse.

Who wants to walk around with a artificial boner depressed anyway?

Johno · Oct 19, 2014

I read, than ED drugs can cause ear problems due to vasodilatation - if thiny blood vessels in inner ear arent in good condition, they can break. It is not due to chemical ototoxic, but physical... or not? (Increasing NO in blood)

Anyway, they tested ED drug as a treatment for T. Unsuccesfully.

http://www.ncbi.nlm.nih.gov/pubmed/19222841

Johno · Oct 19, 2014

Looks like, that NO is antioxidant.

http://www.ncbi.nlm.nih.gov/pubmed/11396476

It seems, damages caused by ED drug is only mechanical - thiny vessels rupture and then hypoxia of parts of inner ear tissues.

Telis · Oct 19, 2014

Take the drugs...it not a big deal if his T get worse..

I didn't know, this but apparently this is true....

"The extent of a person’s suffering with tinnitus has no relation to how loud it is, how soft it is, its pitch, it’s so-called reactivity, its lack of predictability, or whether it is continuous or discontinuous"

This is a quote from here2help....This is guy is backed by dr nagler as knowing more than 99% of experts. So don't worry about T getting worse.

Dangerous advise? I don't know...the volume of your T doesn't matter according to here2help....And if dr nagler says he knows more than 99 percent of experts...well, you make the call!

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