Audion Therapeutics

Discussion in 'Research News' started by nills, May 2, 2014.

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    1. nills
      Barefooter

      nills Member Benefactor

      Location:
      Belgium
      Tinnitus Since:
      11/2009
      Cause of Tinnitus:
      acoustic trauma
      Here is another company working on hearing loss and cell regeneration.

      I think this is the one that discovered that Notch inhibition transforms subcells into haircells.

      nothing new but an other one toput on the radar ;)

      http://www.audiontherapeutics.com/
       
      • Like Like x 2
    2. tomytl
      Grumpy

      tomytl Member Benefactor

      Tinnitus Since:
      10 Years
      Cause of Tinnitus:
      unknown
      yes, it's the compamy Dr. Albert Edge from Harvard working with.
      let's hope for some new findings.. they still stuck in hair cell regeneration
      in adults.
       
      • Optimistic Optimistic x 1
    3. benryu
      Anime

      benryu Member Benefactor

      Location:
      Montreal
      Tinnitus Since:
      12/2008
      It's a very young project, but I am impresseds by their round A funding. Eli Lilly is huge, and this company is well known for being extremly risk averse, they would never invest in something without at least a strong proof of concept.

      What is catching my attention is this sentence: "To date, Audion has identified several compounds that can regenerate hair cells in laboratory–based cell culture assays".

      It means one things that blows my mind:
      We knew that a gene in mice, called Rb1, shuts down the growth of new hair cells early in development. Mature mice were able to regenerate their hair cells when the Rb1 gene was blocked.
      --> this was never tested on human hair cell (to my limited knowledge ^_^), but here it seems they did it according to their statement!!?​

      Maybe this is the reason why Eli Lilly invested money in this company...
      Let's wait & see !
       
      • Optimistic Optimistic x 1
    4. tomytl
      Grumpy

      tomytl Member Benefactor

      Tinnitus Since:
      10 Years
      Cause of Tinnitus:
      unknown
      Audion is arround for some years, they had earlier some partners like Sanofi.
      Now Lilly invested, that's good.
      I guess this kind of companies like Audion,Soundpharma,Roche, Novartis do a lot research in the background.
      I'm very curious about the Genvec/Novartis human trial.
       
    5. blablahhh

      blablahhh Member

      Tinnitus Since:
      1989

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