Frequency Therapeutics — Hearing Loss Regeneration

Discussion in 'Research News' started by RB2014, Dec 8, 2016.

    1. SouthKorean
      No Mood

      SouthKorean Member

      Location:
      South Korea
      Tinnitus Since:
      2017/12/28
      Cause of Tinnitus:
      Stress, Shock
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    2. Rb86

      Rb86 Member

      Tinnitus Since:
      5/31/19
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      Noise
      I live in North Carolina. Where does it say it's doing it and when?
       
    3. Bob90
      Busy

      Bob90 Member Podcast Patron Benefactor

      Tinnitus Since:
      03/2019
      Cause of Tinnitus:
      Overexposure to loud music
      If what I'm remembering is true, even if this solves your hearing loss completely, one's tinnitus could still theoretically stick around since it's "wired in" if you've had it chronically. But I guess we wouldn't know that for sure until Frequency has finished all of their testing.

      I do have hearing loss, but it is very mild across both normal and high frequency ranges, and I feel nerve damage is just as much a culprit as hair cell damage. Still, even if it would ultimately not help me very much, I am hopeful it will help many others and hopefully soon!
       
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    4. jeff W

      jeff W Member

      Location:
      nakatomi plaza
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      04/2012
      Please elaborate.
       
    5. Lucifer

      Lucifer Member Podcast Patron Benefactor Hall of Fame

      Location:
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      Durham, North Carolina, United States, 27713
      Contact: Jaime Cheng, MD

      No date when they are doing it but you could ask. Do you live close by to this place?
       
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    6. FGG
      No Mood

      FGG Member Hall of Fame

      Tinnitus Since:
      01/2019
      Cause of Tinnitus:
      Multi-factorial
      Me too. Jamie Cheng was listed as researcher and in Durham. Duke?

      Oops I see this was already answered. I live really close but don't think I qualify :(.
       
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    7. Rb86

      Rb86 Member

      Tinnitus Since:
      5/31/19
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      About 3 hours. I am excited by this news but at the same time cautious. Not sure I'd jump in. Yes, phase 1 shows safety, but I don't think I'd survive my tinnitus or hearing getting potentially worse.

      I believe their requirements are hearing loss for at least 6 months. I'm 4 months in and same hearing loss, no improvement. So it's likely I'd be a candidate.
       
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    8. Rb86

      Rb86 Member

      Tinnitus Since:
      5/31/19
      Cause of Tinnitus:
      Noise
      Aren't hair cells and nerves one and the same?
       
    9. Josdela
      Curious

      Josdela Member

      Tinnitus Since:
      09/2019
      Cause of Tinnitus:
      Nihl
      It is one of the assumptions, that if the hearing of certain frequencies is recovered, tinnitus can be cured.

      What happens if it does not eliminate tinnitus? I believe that only the OTO-313 would be a candidate to cure tinnitus.

      We just have to wait for the results next year or, as you say, some member of Tinnitus Talk can sign up to the trial and share their experience/progress with all of us.
       
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    10. Lucifer

      Lucifer Member Podcast Patron Benefactor Hall of Fame

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      Let us know if you do sign up and get accepted for the trials.
       
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    11. Rb86

      Rb86 Member

      Tinnitus Since:
      5/31/19
      Cause of Tinnitus:
      Noise
      Absolutely. Assuming there's no major confidentiality contracts (which is quite possible), I'd be letting everyone here know what's up every step of the way.
       
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    12. Auron
      Pacman

      Auron Member

      Location:
      Planet Earth
      Tinnitus Since:
      Spring
      Cause of Tinnitus:
      Acoustic Shock
      University of Michigan Device. One Two Punch.
       
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    13. ChrisBoyMonkey

      ChrisBoyMonkey Member

      Location:
      US
      Tinnitus Since:
      2019
      Cause of Tinnitus:
      Noise
      If you have courage and do friend, you will be doing a lot of people suffering on this site a good service. I don't think anyone would think any less of you if you don't either, nobody wants to make this thing any worse.
       
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    14. Jurger

      Jurger Member

      Tinnitus Since:
      2004
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      Hearing loss
      Why not? Have they asked since they went public?
       
    15. F-u-T

      F-u-T Member Podcast Patron Benefactor

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      Their Twitter announcement says they have already started dosing patients in the phase 2A study.
       
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    16. Lucifer

      Lucifer Member Podcast Patron Benefactor Hall of Fame

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      Wow that was quick. Have some people already been given the drug in Phase 2a?
       
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    17. Daniel Lion
      Ape-like

      Daniel Lion Member Podcast Patron Benefactor Hall of Fame

      Location:
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      Cause of Tinnitus:
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      This is one of the many things I don't get.

      I follow ClinicalTrials.gov religiously... waiting to get a shot at participating.

      Am I understanding correctly that the participants for the trial have already been selected? Or is that process underway now? Clarification please, thanks.
       
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    18. Jurger

      Jurger Member

      Tinnitus Since:
      2004
      Cause of Tinnitus:
      Hearing loss
      No, you can e-mail them for participation.
       
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    19. WickedCarnival

      WickedCarnival Member

      Tinnitus Since:
      Late Autumn 2016
      Cause of Tinnitus:
      Unsure between azithromycin or viral infection
      I wonder how long it will take for FX-322 to be available in Canada?
       
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    20. JohnAdams
      Festive

      JohnAdams Member Benefactor Hall of Fame

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      Hell naw. OTO-413 will probably lower tinnitus with several doses. FX-322 will treat tinnitus, just watch.
       
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    21. JohnAdams
      Festive

      JohnAdams Member Benefactor Hall of Fame

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      Not really. They are both considered to be nerves but the hair cell is a highly specialized type.

      It won't.
       
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    22. JohnAdams
      Festive

      JohnAdams Member Benefactor Hall of Fame

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      That's bullshit. Nobody knows that.
       
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    23. Jurger

      Jurger Member

      Tinnitus Since:
      2004
      Cause of Tinnitus:
      Hearing loss
      There’s hair cells, the nerve endings of hair cells and the auditory nerve. All three are needed for natural hearing, all three can be damaged. New hair cells induced by regenerative medicine do seem to have nerve endings, from what we’ve seen in pre-clinical work from these drugs.
       
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    24. JohnAdams
      Festive

      JohnAdams Member Benefactor Hall of Fame

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      I'm focused on the track.
       
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    25. Heinrich_S7
      Psychedelic

      Heinrich_S7 Member

      Tinnitus Since:
      Uncertain
      Cause of Tinnitus:
      noise exposure
      @JohnAdams Do you think our sentence is almost up?

      Life is going to be so beautiful in silence.
       
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    26. Auron
      Pacman

      Auron Member

      Location:
      Planet Earth
      Tinnitus Since:
      Spring
      Cause of Tinnitus:
      Acoustic Shock
      Music is going to sound so beautiful again!
       
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    27. JohnAdams
      Festive

      JohnAdams Member Benefactor Hall of Fame

      Location:
      Vatican
      Tinnitus Since:
      May 1st 2018
      Cause of Tinnitus:
      Aspirin Toxicity/Possibly Noise
      Hope so. We may not get total silence out of this. Who knows?
      The Frequency Therapeutics people will have some knowledge here in a few months about it. I wish they would do a separate study on people with very little hearing loss but tinnitus. Why wouldn't they? I don't understand their decision making process.
       
    28. tarmaced
      Wtf

      tarmaced Member

      Tinnitus Since:
      2004 (mild) 2018 (not so mild)
      Cause of Tinnitus:
      Ear infections, compounded by noise exposure
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    29. Heinrich_S7
      Psychedelic

      Heinrich_S7 Member

      Tinnitus Since:
      Uncertain
      Cause of Tinnitus:
      noise exposure
      Almost every other drug or treatment on the market is applicable to treating multiple several conditions, I see no reason why FX-322 can't be designated for both hearing loss and tinnitus.
       
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    30. JohnAdams
      Festive

      JohnAdams Member Benefactor Hall of Fame

      Location:
      Vatican
      Tinnitus Since:
      May 1st 2018
      Cause of Tinnitus:
      Aspirin Toxicity/Possibly Noise
      It's all about money.
       
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