Interview with Decibel Therapeutics' New CEO

Discussion in 'Research News' started by beeeep, Jul 18, 2016.

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    1. beeeep

      beeeep Member

      Location:
      Germany
      Tinnitus Since:
      ~2000, but real bad since 06/2015
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      https://www.statnews.com/2016/07/13/hearing-loss-decibel-steven-holtzman
       
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    2. Foncky
      Doubtful

      Foncky Member Benefactor

      Location:
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      Thank you.

      The man seems to understand there's a huge market for his company but only because there's a real medical need.

      Ototoxicity is a major issue so that's good to read about it.
       
    3. Mario martz
      Creative

      Mario martz Member

      Tinnitus Since:
      02/2016
      Ototoxicity?
      i dont understand, they are gonna try to fix others medicaments ototoxicity damage?
       
      • Good Question Good Question x 2
    4. Foncky
      Doubtful

      Foncky Member Benefactor

      Location:
      Europe
      Tinnitus Since:
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      Cause of Tinnitus:
      An explosion, music, and fate.
      I think the key for them is to find something to protect the inner ear from otoxicity. Not to fix the damage afterwards.
       
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    5. Silvio Sabo
      Pooptoast

      Silvio Sabo Member Benefactor

      Location:
      Gothenburg, Sweden
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      05/2006
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      This is somewhat disappointing. At least for us that are already screwed so to say...
       
    6. Foncky
      Doubtful

      Foncky Member Benefactor

      Location:
      Europe
      Tinnitus Since:
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      Cause of Tinnitus:
      An explosion, music, and fate.
      Yes, but don't forget they will also work on noise induced hearing loss and T.

      We can still use a protection against ototoxicity to avoid further damage. The day you HAVE to take an ototoxic drug, that will be a relief.
       
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    7. Mario martz
      Creative

      Mario martz Member

      Tinnitus Since:
      02/2016
      Yes, amen to everything that you said!
       
    8. Silvio Sabo
      Pooptoast

      Silvio Sabo Member Benefactor

      Location:
      Gothenburg, Sweden
      Tinnitus Since:
      05/2006
      Cause of Tinnitus:
      Noise - I think
      If they worked on regeneration that would be useful in ototoxic drugs as well. Instead of protection you would be able to restore your hearing after having to take an ototoxic drug. So I would still much rather see them follow that path than this.
       
    9. Reinier
      Not amused

      Reinier Member Benefactor

      Location:
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      Yes I agree. Why though would they have decided to "go after" the ototoxic prevention route?
      Perhaps they expect results sooner?
      Is my assumption correct that regeneration is more difficult than preventing ototoxic damage in the inner ear?
       
    10. Foncky
      Doubtful

      Foncky Member Benefactor

      Location:
      Europe
      Tinnitus Since:
      03/2004
      Cause of Tinnitus:
      An explosion, music, and fate.
      I guess so. It would be wise for them to focus right now on drugs that have a chance to work quite soon. Then they can go on.

      Anyway, I don't think regeneration will give you back a perfect inner ear, at least not before long. Avoiding damage in the first place is always better.

      The marketing efforts of those companies will be huge. And that's good for us ! People will know about what they do, about our problems. This will attract money and raise awareness in the medical and business worlds.
       
    11. Silvio Sabo
      Pooptoast

      Silvio Sabo Member Benefactor

      Location:
      Gothenburg, Sweden
      Tinnitus Since:
      05/2006
      Cause of Tinnitus:
      Noise - I think
      I don't much care about getting back a perfect inner ear. Just make the noise go away!
       
      • Agree Agree x 6
    12. lapidus

      lapidus Member

      Location:
      Sweden
      Tinnitus Since:
      1999
      Cause of Tinnitus:
      Noise induced
      I thought Decibel Therapeutics was working with neurotrophins?
       
    13. Ian Mac

      Ian Mac Member

      Tinnitus Since:
      2011
      Cause of Tinnitus:
      Vestibular Nueritis, loud music (dubstep)
      That's a good point but as a business they will choose the more sure fire way to see return on investment. Finding a drug that protects the ears is easier than solving the holy grail of hearing loss and Tinnitus, at least as their first project. So many people taking drugs that are ototoxic means if Decible can find a Oto-protective medication they know that every single person taking ototoxic drugs will then also be taking Decibles Oto-protective med and that means serious cash so they for sure have a return on the $52million, if we get to this point then they will move on to address H and T.
       
    14. Silvio Sabo
      Pooptoast

      Silvio Sabo Member Benefactor

      Location:
      Gothenburg, Sweden
      Tinnitus Since:
      05/2006
      Cause of Tinnitus:
      Noise - I think
      I know all that. It's still disappointing.
       
      • Agree Agree x 1
    15. Mentos

      Mentos Member Benefactor

      Tinnitus Since:
      03/2015
      I thought so too, they were about to investigate further in hidden hearing loss and cochlear synaptopathy treatment that Liberaman is working on. That's also what Liberman confirmed to me by email is a field of their research.
       

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