Knopp Biosciences

Discussion in 'Research News' started by attheedgeofscience, May 19, 2015.

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    1. attheedgeofscience
      Uninvolved

      attheedgeofscience Member Hall of Fame

      Location:
      Denmark
      Tinnitus Since:
      Childhood
      Cause of Tinnitus:
      Head Injury
      As members of this forum may know we, @Team Trobalt, are tracking down information on pharmaceuticals involved in potassium channel modulator research. Knopp Biosciences is (probably) another pharmaceutical that most people are not aware of. However, tinnitus is actually mentioned (briefly) on their homepage:

      http://knoppbio.com/research/show.php?2

      Their product pipeline shows the following drug candidates...

      upload_2015-5-19_10-20-9.png

      ...and I have managed to track down that the "Kv7 platform" probably refers to the following compound(s):

      IMIDAZO(4,5-B) PYRIDIN-2-YL AMIDES (as KV7 CHANNEL ACTIVATORS)

      Knopp Biosciences has filed a patent application last year (see attachment) which, again, I believe is concerned with the drug candidate behind the mentioned "Kv7 platform" in the above overview. Interestingly, Trobalt/Retigabine is mentioned within the application.

      As with SciFluor, we will be attempting to contact a senior representative of the company to see if we can get a few more specifics.

      attheedgeofscience
      19/MAY/2015.
       

      Attached Files:

      • Informative Informative x 4
      • Like Like x 3
    2. Calories
      Surrender

      Calories Member

      Location:
      Bangalore, India
      Tinnitus Since:
      March 2015
      Cause of Tinnitus:
      B12 Difficiency, Possibly salycilic poising from fenugreek and ginger
      :thankyousign:

      They are yet to start animal model studies for tinnitus, So anything from them for tinnitus is at least 15 years away!:eek:
       
    3. Nucleo

      Nucleo Member Benefactor

      Tinnitus Since:
      02/2011
      Well to be fair, it's not like anyone else is significantly more advanced in the field of tinnitus.
       
    4. Nucleo

      Nucleo Member Benefactor

      Tinnitus Since:
      02/2011
      Interesting that they are pursuing dexpramipexole for treatment of ALS. Biogen Idec cancelled the project due to poor results in Phase III of their trials with this very same compound.
       

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