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Paulmanlike

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  • P
    Anything to look forward to now apart from Susan shores device? Any biotechs, etc T is piercing again.
    gameover
    Not really. Potassium open drugs maybe, but doubtful. Neurosoft. Far fetched, but who knows.
    P
    Thanks @gameover for reply. Just had a look at neurosoft… what on earth is it?
    P
    When Susan shore says there is a 75% decrease in her patients, is she talking about 1 or all 300 (that was how many ppl were recruited)?
    Ryan Scott
    75% reduction in all her patients would be truly life changing, could you imagine!
    P
    I think the sample size was 99 wasn't it? A 75% reduction in 1 or 2 patients is barely significant but we will have to wait to the publication is released
    N
    That will be the mean (average) if you will
    P
    Eli Lily bought Akouous today.
    CRGC
    More money in hearing research is good news, although Akouos doesn't appear to have much in the pipeline for acquired hearing loss / tinnitus
    P
    Took.ibrofon now I have t in my non t ear. Hopefully its temporary.
    kingsfan
    Do you mean ibuprofen? I think with ibuprofen it is usually temporary. Switch to acetaminophen and start with lowest dose, lower if you can. I am not a doctor.
    P
    Yes. Extended use can be permanent and also hearing loss. Not too worried and its pretty much gone. Obviously the established T rings away still.
    kingsfan
    Ah yes. It seems almost any medication I take affects mine now. I usually don't take anything for headaches until it becomes unbearable. I used to eat ibuprofen like candy.
    P
    Ear irrigated. Always anxious around it. But 2 chunks of wax straight out. Improves the masking at least. Hope everyone is okay!
    P
    How ironic would it be if Auris took off and solved everything
    T
    would be awesome but everything for tinnitus or hearing loss is acute only at the moment, would be a damn shame if it ended up working for acute cases only because we would all be so fucked.
    P
    Miserable fx322 :-(
    L
    I know, I feel like I got kicked in the nuts. I think the takeaway from this is additional doses were worse in weekly succession and next time they should try monthly. They did another Phase 1b trial that showed that a single dose of FX-322 was effective, so that's two Phase 1b trial that shows the single dose was effective. We still have age-related and severe hearing loss trial left.
    L
    I have a feeling the age-related hearing loss will be positive but I'm unsure about the severe category as the drug needs to go deeper in the round window.
    P
    5 days for freq conference, results within 2 weeks for phase 2. Have hope. It's the only thing that keeps me going.
    L
    Same, I hope FX-322 has no problem reaching deeper in the round window with additional doses to be more effective and get rid of tinnitus and hyperacusis.
    P
    Tinnitus getting Intrusive again.. holding on to March with fx322 results. Really hope it's the saviour that Lenire couldnt achieve.
    L
    Same man. It is such a long wait but going through this I hope it was worth it and FX-322 will cure us.
    sensualmosquito
    I hope it helps my terrible hearing and rids me of this ringing.
    P
    2021 guys!! We will find out if hearing restoration is more likely! My bets with frequency therapeutics being the first!
    P
    Carl Lebel said ancedontal reports of patients offering improving of their tinnitus. So they havent treated many people, and uses plural..
    Keith Handy
    And willingly gave an hour of interview time to a specifically tinnitus-themed podcast.
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