Progabide for Tinnitus?

[JasonP]

Some people on this form say they heavily benefited from Trobalt (Retigabine) for their tinnitus. Trobalt is a potassium channel opener. According to Wikipedia, there is a drug called Progabide that works on GABAb receptors. Wikipedia says that GABAb receptors can stimulate the opening of K+ channel which means a potassium ion channel. I know Trobalt is more targeted and a potassium ion channel may be different that a potassium channel but I was just curious. Unfortunately though, Wikipedia does not give a source for GABAb receptors being able open K+ channels and just states it. At any rate, has anyone tried this drug? Do you guys think it is worth a try?

Retigabine works primarily as a potassium channel opener
Source: https://en.wikipedia.org/wiki/Retigabine

Via conversion into GABA, progabide behaves as an agonist of the GABAA, GABAB, and GABAA-ρ receptors.
Source: https://en.wikipedia.org/wiki/Progabide

GABAb receptors:
They can stimulate the opening of K+ channels which brings the neuron closer to the equilibrium potential of K+, hyperpolarising the neuron.
Source: https://en.wikipedia.org/wiki/GABAB_receptor

This is probably like apples and oranges but I figured I would just ask if anyone tried it even for the additional GABAb receptor action.

 

[gotyoubynuts]

Some people on this form say they heavily benefited from Trobalt (Retigabine) for their tinnitus. Trobalt is a potassium channel opener. According to Wikipedia, there is a drug called Progabide that works on GABAb receptors. Wikipedia says that GABAb receptors can stimulate the opening of K+ channel which means a potassium ion channel. I know Trobalt is more targeted and a potassium ion channel may be different that a potassium channel but I was just curious. Unfortunately though, Wikipedia does not give a source for GABAb receptors being able open K+ channels and just states it. At any rate, has anyone tried this drug? Do you guys think it is worth a try?

Retigabine works primarily as a potassium channel opener
Source: https://en.wikipedia.org/wiki/Retigabine

Via conversion into GABA, progabide behaves as an agonist of the GABAA, GABAB, and GABAA-ρ receptors.
Source: https://en.wikipedia.org/wiki/Progabide

GABAb receptors:
They can stimulate the opening of K+ channels which brings the neuron closer to the equilibrium potential of K+, hyperpolarising the neuron.
Source: https://en.wikipedia.org/wiki/GABAB_receptor

This is probably like apples and oranges but I figured I would just ask if anyone tried it even for the additional GABAb receptor action.

Do we have brave Spaniards willing to buy this and try???

 

[JasonP]

Do we have brave Spaniards willing to buy this and try???

Oh wow...I had no idea until now I could not get that in the U.S.! I was actually thinking about asking my doctor about it..oh well...how did you find out it was available in Spain? Is it available anywhere else?

 

[gotyoubynuts]

Oh wow...I had no idea until now I could not get that in the U.S.! I was actually thinking about asking my doctor about it..oh well...how did you find out it was available in Spain? Is it available anywhere else?

Sorry I'm not sure if it's available in Spain but in Spain they sell people all types of drugs without prescription so I thought it's worth checking out.

The Wiki pedia site says it's sold in France... is it only available in France? Why?? but it's under Prescription in France, not freely available

 

[JasonP]

Sorry I'm not sure if it's available in Spain but in Spain they sell people all types of drugs without prescription so I thought it's worth checking out.

The Wiki pedia site says it's sold in France... is it only available in France? Why?? but it's under Prescription in France, not freely available

Yeah that is a good point...I wish it was it approved by France it would be approved in more places. Hey what did you think of the Riluzole drug thing I posted? Do you think it would be worth trying?