Steroids: Prednisone / Dexamethasone / Others (Oral and Injections)

Discussion in 'Treatments' started by tweak, Apr 23, 2012.

    1. IvanRus

      IvanRus Member

      Tinnitus Since:
      04/2017
      Cause of Tinnitus:
      ototoxicity
      Good day, @1MW

      So, having studied a lot of literature on the topic of corticosteroids, I still do not fully understand their pathogenetic validity for problems with the inner ear / spike of tinnitus.

      Due to what they can favorably affect the course of tinnitus and damage to the inner ear ?! Only due to its anti-inflammatory properties, decongestants?

      Although, if you think about it, corticosteroids increase the level of cortisol - a stress hormone, a destructive hormone.

      Can you explain, can it affect MDMA, or genes?

      You also mentioned that he is removing potassium, and NAC is removing zinc and magnesium.
      What products should I use to replenish stocks?

      Thank you
       
    2. IvanRus

      IvanRus Member

      Tinnitus Since:
      04/2017
      Cause of Tinnitus:
      ototoxicity
      I take prednisolone at a dose of 25 mg the third day in the mornings from a spike a week long.

      While I do not feel any effect, should I continue?
       
    3. David077
      Creative

      David077 Member

      Tinnitus Since:
      2013
      Cause of Tinnitus:
      stress, benzo/clonozepam + clonidine, maybe infection
      Maybe you T does not comes from inner ear problem. What caused your spike? Which type of noises you have in your ears or head?
       
    4. IvanRus

      IvanRus Member

      Tinnitus Since:
      04/2017
      Cause of Tinnitus:
      ototoxicity
      @1MW

      Tell me, enlightened people!

      Can the use of corticosteroids (prednisolone) itself be harmful in tinnitus?

      After all, it excessively increases blood circulation in the cochlear zone, removes potassium from the body. Is it harmful to the hair cells?!
       
    5. IvanRus

      IvanRus Member

      Tinnitus Since:
      04/2017
      Cause of Tinnitus:
      ototoxicity
      How do you take prednisolone?
      Strictly in the morning hours from 6 to 8 o'clock in the morning?
      Is it possible to take it a little later, say, at 12 o'clock?
      Or divide the dose throughout the day?
      Did you have a similar experience?
       
    6. 1MW
      No Mood

      1MW Member

      Tinnitus Since:
      2008 but cured and relapsed from benzos
      Cause of Tinnitus:
      ssnhl/benzos/unknown
      Taking prednisone 8 o'clock in the morning has the least side effects.
       
    7. IvanRus

      IvanRus Member

      Tinnitus Since:
      04/2017
      Cause of Tinnitus:
      ototoxicity
      In what dosages and according to what scheme did you take prednisolone?
      30 mg at your sufficient dose?
       
    8. IvanRus

      IvanRus Member

      Tinnitus Since:
      04/2017
      Cause of Tinnitus:
      ototoxicity
      n what country did they appoint you?
      You were prescribed prednisolone, not methyl prednisolone, not metipred, not dexamethasone, but prednisolone?
      Did it help you?
      I drink 30 mg, and I think it's not a small dosage, it often mentions a dose of 60 mg.
       
    9. IvanRus

      IvanRus Member

      Tinnitus Since:
      04/2017
      Cause of Tinnitus:
      ototoxicity
      What was your dosage?
      Did you experience any side effects?
      Was it possible?
       
    10. IvanRus

      IvanRus Member

      Tinnitus Since:
      04/2017
      Cause of Tinnitus:
      ototoxicity
      Has anyone had an increase in tinnitus from taking prednisolone?

      It removes potassium from the cells, is it dangerous?

      Why is it mentioned in some sources, as a preparation from which tinnitus is possible?
      In the official instruction nothing is said about tinnitus as a side effect.
       
    11. IvanRus

      IvanRus Member

      Tinnitus Since:
      04/2017
      Cause of Tinnitus:
      ototoxicity
      Hi, did this dosage (20 mg of prednisolone for 5 days) end up working?

      Did Spike return to the baseline?
       
    12. Rings-a-Bell

      Rings-a-Bell Member

      Location:
      Barbados
      Tinnitus Since:
      April 2016
      Cause of Tinnitus:
      Accoustic Trauma
      I found that taking 60mg+ per day of prednisolone cut my T way down after 1 day. When I stopped after 2 days, it reverted to baseline. I did this twice, during spikes. As for side effects, it might be coincidence but my weight set point seems to be 5-10 pounds higher than it used to before I tried this. Although it helps my T, it not a long term solution and it isn't even worth it for a day or two of relief.
       
    13. IvanRus

      IvanRus Member

      Tinnitus Since:
      04/2017
      Cause of Tinnitus:
      ototoxicity
      Interesting. That is, the effect of the device immediately passes after the drug is discontinued?

      How do you generally cope with spikes, if not hormones? What's the longest time You've had?

      Are you trying to calm down or something?
       
    14. Rings-a-Bell

      Rings-a-Bell Member

      Location:
      Barbados
      Tinnitus Since:
      April 2016
      Cause of Tinnitus:
      Accoustic Trauma
      I got my Tinnitus about 2 years ago. I have hearing damage at 4000hz (it is reduced by 45db - considered moderate), and that is where my tone is. If I expose my ears to loud noise, I generally get a spike the next day that lasts 1-2 weeks. I am currently having a spike right now as I went to a restaurant for a business meeting on Tues night that was 70-80db. In general, I cannot tell if a spike is because my T is actually louder or because my brain is paying more attention to it. I can say that previous to this spike, I was actually further down the habituation trail than I have ever been before. I had several days last week where I only noticed my T once or twice per day! Normally I notice it several hundred times per day, all day long.

      Prednisone reduces inflammation. My guess is that there is an element of inflammation in my T process. To try and get my inflammation reduced naturally I eat a lot of fish oil capsules. Maybe they are what is helping me habituate on my good days like last week? Maybe not. Maybe they just give me the illusion of doing something proactive which allows my mind to stop fixating on it. I will say that just to be safe, I double my consumption of fish oil during a spike.
       
    15. IvanRus

      IvanRus Member

      Tinnitus Since:
      04/2017
      Cause of Tinnitus:
      ototoxicity
      How old are you, if not secret?
      It took you a while to come to this state of habituation and adaptation?
       
    16. Rings-a-Bell

      Rings-a-Bell Member

      Location:
      Barbados
      Tinnitus Since:
      April 2016
      Cause of Tinnitus:
      Accoustic Trauma
      I am 47. I have had my T for 2 years. It's really only in the last 2 months that I have come to a point where I can go most of the day without thinking about it. And that is a fragile state. If I expose myself to too much noise... say over 70db for an hour or two it gets worse for a few days or weeks.

      I suspect that a lot of habituation has to do with just not worrying about it. My spikes come when I do something that makes me worry I could have hurt my ears more. For example there is no physiological reason why 70-80db for an hour would cause further hearing damage. Normally it takes 80db for something like 8 hours to cause hair cells to die. And yet it affects me, because it makes me worry about it and focuses my attention on it.

      I will say this though.. the predenisone affect is real, not imagined. I know this because when on high doses of prednisone my hearing test at 4000hz was consistently 10db better than normal. This measurement was done through dozens of self administered tests. Although self-administered tests have a margin of error, there was a clear difference. I could hear softer sound levels consistently then that I have never ever been able to hear when not on it.
       
    17. IvanRus

      IvanRus Member

      Tinnitus Since:
      04/2017
      Cause of Tinnitus:
      ototoxicity
      It's amazing.
      In what doses did you take Prednisolone in tablets?

      After the course was completed, did everything return to normal?

      What was your longest spike?

      Have you ever used benzos (xanax, clonazepam)?
       
    18. Rings-a-Bell

      Rings-a-Bell Member

      Location:
      Barbados
      Tinnitus Since:
      April 2016
      Cause of Tinnitus:
      Accoustic Trauma
      I took 60mg per day for 2 days. The first time it was prescribed by an ENT, the next time I just used my left over pills. I can't remember anymore what the exact breakdown was (?20mg 3x per day is my guess). I wanted to be on them for short enough a time that I didn't need to taper the dose and could just stop.

      Hard to say what the longest spike is... they have no real defined end point. In fact... the more you try to measure them, the longer they will last. My T never goes away, if I listen for it, it is there, so if I try to actively monitor my spike, it will seem to never end. It is more of a "hey... its 8pm and I guess I haven't noticed it too much today, the spike must be over".

      No benzos. I am not depressed.
       
    19. IvanRus

      IvanRus Member

      Tinnitus Since:
      04/2017
      Cause of Tinnitus:
      ototoxicity
      30 mg per day of prednisolone, is this a normal, effective dose?

      Has someone been prescribed this dose?
       
    20. Rings-a-Bell

      Rings-a-Bell Member

      Location:
      Barbados
      Tinnitus Since:
      April 2016
      Cause of Tinnitus:
      Accoustic Trauma
      FYI, 30mg did nothing for my T, had to be over 60mg... which is nothing you would ever want to do as a long term therapy.
       
    21. TLion

      TLion Member

      Tinnitus Since:
      2006
      Cause of Tinnitus:
      stress/loud concert
      I had a serious increase of my Tinnitus 2 months ago. Because I panicked and had severe anxiety I did not take Prednisone because of the mental issues. Now I am on my second day of a five day course with 50mg Prednisone. My doc says 5 days 50mg don't need to be tapered so I can stop without taper. It's that right? Or should I taper down?
       
    22. TLion

      TLion Member

      Tinnitus Since:
      2006
      Cause of Tinnitus:
      stress/loud concert
      Anyone?
       
    23. lena_

      lena_ Member

      Tinnitus Since:
      2018
      Cause of Tinnitus:
      ear infection
      your doctor is right. well, i think he is, i did not study medicine but as far as i understand it it is ok-
      also from my experience: i took 100mg for 5 days (each day early in the morning 100mg), no tapering and everything was fine.
       
    24. TLion

      TLion Member

      Tinnitus Since:
      2006
      Cause of Tinnitus:
      stress/loud concert
      I am on my 4th do of Prednisolone 50 mg and my Tinnitus spiked. Spikes are normal during Prednisone intake, is that right? Tomorrow would be my last day and then stop according to my doc. My T can be mild but also severe. It's a loud static white noise ATM.
       
    25. IvanRus

      IvanRus Member

      Tinnitus Since:
      04/2017
      Cause of Tinnitus:
      ototoxicity
      Why did you have a spike of tinnitus?
      On what day did you start taking prednisolone?
      What effects do you feel? Do you say prednisolone has increased your tinnitus?
      What about anxiety or insomnia, you have not experienced these side effects?
      What is the current rate of this course of steroids after the beginning of tinnitus in you?
       
    26. IvanRus

      IvanRus Member

      Tinnitus Since:
      04/2017
      Cause of Tinnitus:
      ototoxicity
      Can prednisolone worsen hearing or strengthen tinnitus?
      Is it really ototoxic if taken in a dose of 60 mg?
       
    27. IvanRus

      IvanRus Member

      Tinnitus Since:
      04/2017
      Cause of Tinnitus:
      ototoxicity
      This scheme helped you with tinnitus? Have you experienced side effects after cancellation?
       
    28. IvanRus

      IvanRus Member

      Tinnitus Since:
      04/2017
      Cause of Tinnitus:
      ototoxicity
      Did anyone have skin rashes in the form of pimples from prednisolone?
       
    29. IvanRus

      IvanRus Member

      Tinnitus Since:
      04/2017
      Cause of Tinnitus:
      ototoxicity
      Has anyone had tinnitus after a sharp withdrawal / withdrawal of prednisolone?

      Then it returned to its previous level?
       
    30. Nice
      Bookworm

      Nice Member Benefactor

      Location:
      Bay Area, Ca
      Tinnitus Since:
      06/2018
      Cause of Tinnitus:
      Sudden hearing loss
      I just finished prednisone treatment and there's no difference for me. Tomorrow I'm getting an eardrum injection . This will be the first of three injections.
       

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