Tinnitus Retraining Therapy Trial (TRTT)

[Tinnitus Talk]

Tinnitus Talk submitted a new resource:

Tinnitus Retraining Therapy Trial (TRTT) (version 1.0) - To assess the efficacy of TRT as a treatment for severe debilitating tinnitus.

The primary purpose of the Tinnitus Retraining Therapy Trial (TRTT) is to assess the efficacy of tinnitus retraining therapy (TRT) as a treatment for severe debilitating tinnitus. TRT is a non-medical intervention that uses directive counseling (DC) and sound therapy (ST)to habituate the patient's associated negative emotional reactions to tinnitus, its perception, and ultimately, its impact on the patient's life.


Estimated Enrollment:228
Study Start Date:July 2011
Estimated Study...

Read more about this resource...

 

[amandine]

Just wondered if there were any results on this yet.

 

[Markku]

Just wondered if there were any results on this yet.

It is currently recruiting participants:

https://www.clinicaltrials.gov/ct2/show/NCT01177137

 

[LadyDi]

FYI, regarding the above study: Appears that you must be eligible to receive your medical care through Dept of Defense. So this study appears to be for U.S. veterans or (maybe) their dependents.

 

[Frédéric]

Status: this study has been completed.
Study completion date: February 2017

Maybe one of our American friends could ask the designers of this trial for the results.

By the way, I found a big description of the protocol:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210573/

 

[GregCA]

Maybe one of our American friends could ask the designers of this trial for the results.

I don't think they restrict their answers to just US citizens/residents... Have you tried contacting them?

Personally I've had pretty bad luck getting any response from any clinical trial contact listed on the contact info pages (read: I've tried a handful of times and never got any response), so I'm a bit burned by the process, but you could give it a shot if you feel luckier than me.

I think this is the equivalent study on CT: https://clinicaltrials.gov/ct2/show/NCT01177137?term=Roberta+Scherer&cond=Tinnitus&rank=1

I read a while back that it was unfortunately pretty common for studies to not have results published (it doesn't have a high priority once the lab has results), and there was a discussion about how to incentivize the publication.

 

[threefirefour]

I don't think they restrict their answers to just US citizens/residents... Have you tried contacting them?

Personally I've had pretty bad luck getting any response from any clinical trial contact listed on the contact info pages (read: I've tried a handful of times and never got any response), so I'm a bit burned by the process, but you could give it a shot if you feel luckier than me.

I think this is the equivalent study on CT: https://clinicaltrials.gov/ct2/show/NCT01177137?term=Roberta+Scherer&cond=Tinnitus&rank=1

I read a while back that it was unfortunately pretty common for studies to not have results published (it doesn't have a high priority once the lab has results), and there was a discussion about how to incentivize the publication.

>TRT trial won't publish results or tell you people how it went

Wow I wonder why. Really makes you think doesn't it? :^)

 

[Markku]

I have made some inquiries about this, will post if / when I hear back.

 

[Fabrikat]

Personally I've had pretty bad luck getting any response from any clinical trial contact listed on the contact info pages (read: I've tried a handful of times and never got any response), so I'm a bit burned by the process, but you could give it a shot if you feel luckier than me.

That's interesting. Me too! It makes you wonder why they bother putting contact details up there when they have no intention of responding to public queries. Must be some kind of protocol they're obliged to follow as part of the publicity process.

 

[Paulmanlike]

This must be the only trial I hope shows poor efficacy. If it's shown to be effective, which I doubt it is, will not show how urgent a proper and real treatment for tinnitus is!

 

[threefirefour]

This must be the only trial I hope shows poor efficacy. If it's shown to be effective, which I doubt it is, will not show how urgent a proper and real treatment for tinnitus is!

Fully agree. This trial shows a very bad precedent. However considering that there is no publications of the success of this trial, which considering the business model of TRT, and which would be the first thing they would do, it's safe to assume we don't need to worry.

 

[Greg Sacramento]

http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD011795.pub2/full

 

[PaulBe]

This must be the only trial I hope shows poor efficacy. If it's shown to be effective, which I doubt it is, will not show how urgent a proper and real treatment for tinnitus is!

Medicine likes cost-efficiency, particularly Public Medicine. TRT may or may not have equal application to everybody, but if a benefit can be "proven" to enough people then those left behind can simply drop through the cracks or pay their own way. I think the price-gouging that goes on with sound devices makes even TRT an expensive proposition for (nominally) free Public Health systems too. Were we to became a net drain on Social Security systems through inability to work/pay tax, recurring acute care presentations etc, the the cost/benefit ratio would however change overnight.

 

[Markku]

OK, so I found the following:

• As of now, they are in the process of writing the main results paper,
• They hope to submit it for peer review by the middle of October,
• They estimate, given the time the peer review process can take, that the results are published in the beginning of 2018, at the earliest.

 

[threefirefour]

Awesome they're writing the results paper. Here's hoping it fails miserably

 

[Frédéric]

I found this article today. I can't copy and paste the abstract, it's locked. I can only provide the link (hoping it will remain published)
Lessons learned conducting a multi-center trial with a military population: The Tinnitus Retraining Therapy Trial
Link: http://journals.sagepub.com/doi/abs/10.1177/1740774518777709

 

[GregCA]

I found this article today. I can't copy and paste the abstract, it's locked. I can only provide the link (hoping it will remain published)
Lessons learned conducting a multi-center trial with a military population: The Tinnitus Retraining Therapy Trial
Link: http://journals.sagepub.com/doi/abs/10.1177/1740774518777709

It's the first time I come across a study that uses the Results section/paragraph to describe exhaustively all of the challenges they had to face during the study while allocating 0 words for actual results.

 

[Aaron123]

I found this article today. I can't copy and paste the abstract, it's locked. I can only provide the link (hoping it will remain published)
Lessons learned conducting a multi-center trial with a military population: The Tinnitus Retraining Therapy Trial

Not sure why the link or paper would not 'remain published'.

It's the first time I come across a study that uses the Results section/paragraph to describe exhaustively all of the challenges they had to face during the study while allocating 0 words for actual results.

The journal is called "Clinical Trials" and deals with trial design and implementation so the results section is what you would expect in that context.

 

[GregCA]

The journal is called "Clinical Trials" and deals with trial design and implementation so the results section is what you would expect in that context.

Ah, yes, that makes sense then... I had the wrong expectations.

 

[Frédéric]

Results:
https://jamanetwork.com/journals/jamaotolaryngology/article-abstract/2734346

Related to this post:
https://www.tinnitustalk.com/thread...-tri-2019-conference.34029/page-5#post-510025

 

[threefirefour]

Awesome they're writing the results paper. Here's hoping it fails miserably

Well, I got good news for 2017 me.