I recently picked up a very serious and hard to get rid of sinus infection. In addition to IV antibiotics my infectious disease doctor prescribed tobramycin nasal rinse twice a day. I have always had a low level of tinnitus from high frequency hearing loss. I had pretty much acclimated to it, and it rarely bothered me. Within 2 applications of the tobramycin rinse, my tinnitus atleast tripled. the ID doctor says there is little chance it could be from the tobramycin rinse because it was only 2 doses and it was a rinse not a shot. After the fact i found out how ototoxic tobramycin is. But i dont see much info about using it as a rinse. Does anyone have any experience with this? Thanks!