What Were the Advances in Research for 2014?

Discussion in 'Research News' started by generalfuzz, Dec 19, 2014.

tinnitus forum
    1. generalfuzz

      generalfuzz Member Benefactor

      Tinnitus Since:
      01/2013
      Cause of Tinnitus:
      ototoxic reaction to relafen
      I would love to see a summary of advances in tinnitus/hyperacusis research for 2014. I tend to get caught up in the day to day posts - I've lost sight if we've made significant (or insignificant) strides this year.
       
      • Agree Agree x 4
    2. Hudson
      Cowboy

      Hudson Member Benefactor

      Tinnitus Since:
      2003
      I can give you my quick one-off summary:

      In 2014, more late stage clinical trials for tinnitus treatments were either in operation or being prepared to start than ever before. There are clinical trials for multiple modes of treatment, from vagus nerve stimulation, to intratympanic injection of esketamine for acute onset tinnitus, to development of AUT00063, a potassium channel modulator, which would treat even chronic tinnitus.

      GenVec has started the first ever hair-cell restoration and hearing restoration trial ever. I can't understate how huge that is.

      Published papers in the field of tinnitus have nearly tripled from 10 years ago.

      There are several companies investigating methods of treating acute hearing loss, menieries disease and otoprotection.

      The annual TRI conferences continue to attract more people and better talent from multiple different academic fields.

      Data collection, known as the TINNET, began this year. This will help to seriously categorize the different etiologies of tinnitus. A lot of the failures of previous investigations and trials can be blamed on poor definition of tinnitus sub-groups and what the target treatment audience is.

      On this very site here, have started our own "mini-trial", pulling a Barry Marshall, (a microbiology pathologist who famously drank infected broth to prove to the scientific community that ulcers were often caused by bacteria and not "stress" because he lacked people he could ethically experiment on) people have began taking trobalt off label prescribed by various medical people because of the anecdotal and academic evidence that trobalt may possibly treat tinnitus. We have seen a good degree of success with many of the people who have taken part in this courageous experiment.

      In fact, we're currently in contact with researchers about setting up an actual study to investigate the potential for trobalt to treat tinnitus patients.

      So, if you are afraid that 2014 has been a slow year, you'll be quite surprised to find the opposite. Hold on to your pants, because 2015 will be cool with preliminary efficacy data from Autifony being released this summer.
       
      • Like x 7
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    3. Ken219
      No Mood

      Ken219 Member

      Location:
      New York Area
      Tinnitus Since:
      Summer of 1990
      Cause of Tinnitus:
      Noise exposure?
      Hopefully people that were having bad 'T' in 2013 have habituated.
       
      • Agree Agree x 1
    4. Robb
      Question it

      Robb Member Benefactor

      Location:
      Germany
      Tinnitus Since:
      09/2013
      I like this: 'Hold on your pants' I supplement it with: Fasten your seatbelts
       
      • Funny Funny x 3
    5. generalfuzz

      generalfuzz Member Benefactor

      Tinnitus Since:
      01/2013
      Cause of Tinnitus:
      ototoxic reaction to relafen
      • Agree Agree x 1
    6. Fenas

      Fenas Member

      Tinnitus Since:
      11/2014
      @Hudson is there a foundation that we can trust and donate money to? Not like the foundations that take half of the money to fill their pockets.
       
    7. newfie
      Inspired

      newfie Member

      Location:
      Canada
      Tinnitus Since:
      10/2007
      Cause of Tinnitus:
      Acoustic trauma (gun)
      When I got tinnitus and my hearing was damaged in 2007 I was very upset to see nearly nothing being done to combat tinnitus or hearing loss. Hair cell regeneration was only an idea at the time.

      Times have changed.
       
      • Like Like x 5
    8. wizman

      wizman Member

      Location:
      Paris (france)
      Tinnitus Since:
      07/1987
      Cause of Tinnitus:
      fireworks
      Best cure for T is "no cure"
      Meditate this statement. ....
       
      • Agree Agree x 2
    9. skoupidis

      skoupidis Member

      Tinnitus Since:
      09/2014
      Cause of Tinnitus:
      Acoustic trauma or mvc
      How well known this is... Best cure? Not by far. Best way to cope? Perhaps, but only IF and WHEN one can manage it.
       
      • Like Like x 1
    10. rainman
      Curious

      rainman Member

      Location:
      Tallinn/Helsinki
      • Informative Informative x 1
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    11. tom1989

      tom1989 Member

      Tinnitus Since:
      11/11/2014
    12. iGL0CK

      iGL0CK Member

      Location:
      Poland
      Tinnitus Since:
      09/2013 > 10/2014
      Cause of Tinnitus:
      Acoustic trauma > Don't know, maybe new headset
      Not always. T is recorded in the memory of brain, so restoration of hearing can not eliminate it.

      Sorry for my english.
       
    13. nills
      Barefooter

      nills Member Benefactor

      Location:
      Belgium
      Tinnitus Since:
      11/2009
      Cause of Tinnitus:
      acoustic trauma
      actually there is one way of thinking that suggests that if the ear works again, the brain will need to proces these new sounds and it will overwrite the T in those frequencies.
       
    14. EddyLee
      Tolerant

      EddyLee Member

      Tinnitus Since:
      2013
      I think if one's T is caused by hearing loss then the restoration of hearing should change or stop his T as brain is plastic and it should re-adapt again.
       
    15. skoupidis

      skoupidis Member

      Tinnitus Since:
      09/2014
      Cause of Tinnitus:
      Acoustic trauma or mvc
      Finally, a logical thinking about brain-Tinnitus... It goes away the same way it came! By brain adaptation. Why shouldn't it?

      Merry Christmas everyone!
       
      • Agree Agree x 3
    16. sanjay doodani
      Amused

      sanjay doodani Member Benefactor

      Location:
      New Delhi India
      Tinnitus Since:
      July 2014
      Cause of Tinnitus:
      Suspect vit d deffeiciency stress high bp ,prediabetic, high stress
      I do agree restoration of hearing should also reduce tinnitus
       
    17. tom1989

      tom1989 Member

      Tinnitus Since:
      11/11/2014
      With that in mind...do we believe that there will be a distinct cure for tinnitus before the possibility of restoration of hearing?
       
    18. SoulStation
      No Mood

      SoulStation Member Ambassador Team Tech

      Location:
      New York
      Tinnitus Since:
      2012
      Cause of Tinnitus:
      Noise / Possible Medication
      I think it is safe to assume that they are both going to take a while (not to say we shouldn't be progressive in research and development and fast track any possible 'cures' or viable treatments). As far as who will reach the "finish line" first it's anybody's best guess.
       
    19. Neil991
      Curious

      Neil991 Member

      Tinnitus Since:
      09/2014
      Looks tricky as most people like me cannot pin point on an underlying condition. Hope there is some drug which just makes the noise go away no matter what the underlying condition.

      Come on scientists......you cloned animals, reached the moon......curing Tinnitus cannot be so hard.

      Hope we have some major strides in 2015-2016 and a cure by 2017-2018.
       
      • Like Like x 2
      • Optimistic Optimistic x 1
    20. David King
      No Mood

      David King Member Benefactor

      Location:
      Sweden
      Tinnitus Since:
      Dec 2011
      I remember reading about several cases with elderly people with hearing loss and tinnitus getting hearing aids, where they reported that they not only could hear better, but their tinnitus decreased aswell.
       

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