AUT00201 — Autifony Therapeutics

Autifony are back with a new Kv3 potassium ion channel compound. This one is for schizophrenia and "hearing disorders." I wonder what "hearing disorders" they are referring to.

This was announced today:

Autifony Therapeutics announces commencement of a Phase I study of AUT00201, a novel Kv3 modulator for schizophrenia and hearing disorders

 

Some additional information:

They have another Kv3.1/3.2 drug that is in the process of completing its Phase 1 by end of this year - AUT00206 (not to be confused with AUT00201) - which is designated for fragile X syndrome.

I’m curious how these two compounds differ since they act on the same ion channels and only AUT00201 includes verbiage surrounding “hearing disorders”.

 

Phase 1b underway for AUT00201 in myoclonus epilepsy & ataxia:

Autifony Therapeutics announces commencement of a US Phase Ib study of AUT00201, a novel Kv3 modulator, in Progressive Myoclonic Epilepsy-7 (EPM7)