Cortical Surface Plasticity Promotes Map Remodeling and Alleviates Tinnitus in Adult Mice

Animal study on electrical activation of the cortex after hearing loss induced tinnitus.

→ Cortical Surface Plasticity Promotes Map Remodeling and Alleviates Tinnitus in Adult Mice

 

God I’m so happy for those mice being cured.

 

Mice have all the luck.

 

Are you a man or a mouse?

 

At this rate we're going to make mice immortal with all the testing we do on them.

Oh wait...

 

How are they determining whether the mice have tinnitus? If they’re using either behavioral tests or acoustic startle reflex to define the presence of tinnitus, then this study doesn’t do much for me I’m afraid.

 

It doesn't do much for you? Maybe because you are not a mouse?

 

If only I was a mouse! Fudge.

 

Full paper:

Cortical surface plasticity promotes map remodeling and alleviates tinnitus in adult mice

 

Where do we go to get this done? I'll hold 'em up to do it.

 

How long do you think it will take until they try this on a human?

 

To me this is electrical stimulation of the auditory cortex. It's already been done non-invasively in humans.

 

2.7. Conditioned active-avoidance task as a behavioral measure of tinnitus

As expected.



I can’t wait till the day arrives when we can objectively diagnose and detect tinnitus (with great reliability) in both human and animals without having to resort to subjective and unreliable self-reports and behavioral tests to assess tinnitus and potential solutions. Because right now, there is no outcome measure that is reliably applicable to both human and animal studies in a way that gives us consistent results, nor is there a way to establish a consistent benchmark for comparison between the two.

There’s no reason to automatically assume that it will undoubtedly work on humans.