Electrical Ear Canal Stimulation as a Therapeutic Approach for Tinnitus — A Proof of Concept Study

There were 66 patients, with just under 50% improving. Women and those with bilateral tinnitus fared best. The number reporting worsening was not clinically significant, i.e., just by chance/variations.

→ Electrical Ear Canal Stimulation as a Therapeutic Approach for Tinnitus — A Proof of Concept Study

 

What is compensated tinnitus?

 

From my reading of the study, I found the following: "habituated/compensated (below 47 points) and unhabituated/decompensated."

This indicates to me that the researchers are using habituation and compensation as equivalent terms. And in contrast, those who have not habituated to tinnitus are considered decompensated.

It's a bit late for me to take a deep dive into the entire study, but it looks interesting. I don't see mention of which nerve or nerves they were targeting (vestibular, cochlear, or perhaps trigeminal which is further afield). Or perhaps the mechanism related to electrical stimulation is not directly targeting those nerves?

In any case, I'll read it more thoroughly. Thanks for the original post, @Nick47.

 

This is part of the preparation work for the INTAKT study, where they look to develop an implant. It is the third such company I know of doing this.

Their aims were to reduce tinnitus and experiment with different electrical waves to see what worked best. Broadly speaking, it targets the cochlea, with the implant designed to stimulate through the round window.

 

This sounds amazing! How do we get someone actually to do this in practice, or is this something that would require FDA approval, etc.?

 

Only 3 days and 10 minutes each session? These are really good results.

 

It's experimental, so not publicly available. Only if you got a good contact with a researcher.

I would say they are, although weren't the results taken straight after the session? It was only the ear canal, so it was even better. To me, this seems the best future treatment. I would be fighting to get into a clinical trial.

 

Dang, this would be great if it worked! I hope there will be more studies with this.

 

I like that one guy from the study had his tinnitus disappear.

 

I agree 100%. This appears to be the most effective, realistic, and practical treatment on the horizon.

Compensated tinnitus is when tinnitus is not particularly intrusive.

 

’Kompensierter Tinnitus’ is German for a tinnitus that doesn't bother.

 

If there ever were a clinic trial, do you think they'd accept participants from outside of Germany?

 

No, but if you live in America, I would follow Matthew Carlson and Hamid Djalilian and contact them to participate in their clinical trials.

 

Nice find, @Nick47.

I'm glad Heidi Olze et al. are back on the scene, especially as they're referencing the Feng, Djalilian et al. feasibility study from 2019 for a similar intervention—the more, the merrier.

 

I wonder why women fared better. I also wonder how far away this treatment is. Will it beat Dr. Shore to the punch?

 

The study mentions the difference in body fat and water content between men and women, changing conductivity.

 

Cheers. Reading is getting harder with visual snow syndrome.