Inner Ear Hair Cell Regeneration — Maybe We Can Know More

Discussion in 'Research News' started by Hopeful, Sep 6, 2013.

    1. NuNu

      NuNu Member

      Tinnitus Since:
      10/27/17
      Cause of Tinnitus:
      Firing guns
      But what about in woman?
       
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    2. Rubenslash

      Rubenslash Member

      Location:
      Zurich
      Tinnitus Since:
      04/2016
      Cause of Tinnitus:
      Bad luck and bad decisions
      On what do you base your statement? Seems like this is the first time you hear about HC regeneration so stop making silly predictions based on nothing.
       
      • Agree Agree x 1
    3. Artur
      Wishful

      Artur Member

      Tinnitus Since:
      29/06/2017 or 30/06/2017
      Cause of Tinnitus:
      Noise Exposure
      Specially now with the new biotechnologies coming at the turn of this decade, with CRISPR and new forms of gene therapies.
       
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    4. Flamingo1

      Flamingo1 Member Benefactor

      Location:
      Orlando, FL
      Tinnitus Since:
      4-15-2017
      Cause of Tinnitus:
      Acoustic trauma
      You must be planning on dying soon.
       
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    5. jeff W

      jeff W Member

      Location:
      nakatomi plaza
      Tinnitus Since:
      04/2012
      They won't believe even when it's done.
       
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    6. grate_biff
      In pain

      grate_biff Member Benefactor

      Location:
      Moss, Norway
      Tinnitus Since:
      09/2014
      Cause of Tinnitus:
      Acoustic trauma using headphones
      One can be well informed and positive.
      One can be uninformed and positive.
      One can be well informed and sceptic/negative.
      One can be uninformed and negative.

      You, sir are the latter, and just a wast of space, I´m afraid!
       
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    7. dingaling
      Asleep

      dingaling Member

      Location:
      London UK
      Tinnitus Since:
      2016
      Cause of Tinnitus:
      unknown, probably loud music
      I have in my possession industry standard and benchmarked Springer books which publish peer-reviewed research about hearing in animals and man at the molecular level so these people who have conducted the research know what they're talking about
       
    8. dingaling
      Asleep

      dingaling Member

      Location:
      London UK
      Tinnitus Since:
      2016
      Cause of Tinnitus:
      unknown, probably loud music
      Sticks and stones....
       
    9. dingaling
      Asleep

      dingaling Member

      Location:
      London UK
      Tinnitus Since:
      2016
      Cause of Tinnitus:
      unknown, probably loud music
      Yes, I will probably die before you - who knows?;)

      I look forward to the clinical trials en masse on real people and the trials will be such a success that deafened people will be queuing up for surgery. ;):LOL:

      I wager this queue won't happen in my remaining lifetime
       
    10. acufenero
      Starving

      acufenero Member

      Tinnitus Since:
      August 2014
      Cause of Tinnitus:
      Acoustic trauma
      At least he's funny... or trying to!

      I suggest you all not to waste a single more minute with him ;)
       
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    11. Benoves

      Benoves Member Benefactor

      Tinnitus Since:
      26-9-2017
      Cause of Tinnitus:
      Unknow possibly noise trauma
      There are many companies on the run i quess, so why not? Atm Im trying to habituate with my T, but hoping 10 years from now there Will be a cure, at least for T.
       
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    12. jeff W

      jeff W Member

      Location:
      nakatomi plaza
      Tinnitus Since:
      04/2012
      There once a lived a great mind who warned us to constantly revise our beliefs with respect to disease processes in the ear, (unlike ours) his generation made "huge" leaps in disorders of the ear. There was Harold Schuknect and there is everyone else. Had he lived today, I have no doubt he would be involved in disruptive technology to repair the damaged ear. This chapter from Baloh on Schuknect's quest against quackery in Otology for everyone's book collection.

      upload_2017-11-9_19-9-56.png


      http://docdro.id/HSyXV0L
       
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    13. Kate Winstol
      Sporty

      Kate Winstol Member

      Tinnitus Since:
      1902
      THIS!
       
    14. RB2014
      Confused

      RB2014 Member Benefactor

      Location:
      US
      Tinnitus Since:
      12/2014 became noticable
      Cause of Tinnitus:
      Loss of hearing and then stress and anxiety
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    15. IAmCalifornia
      Wishful

      IAmCalifornia Member Benefactor Hall of Fame

      Location:
      Pennsylvania
      Tinnitus Since:
      this year
      Cause of Tinnitus:
      i wish i knew
      nah I disagree my ENTs were dirtbags, I wanted to punch one or kill so bad. Still do but that's just because of my deteriorating mental state (thanks tinnitus, the gift that keeps on giving).

      I wait and wait and wait, MONTHS, several of them... and they see me for 2 minutes? ZERO effort to find out, potentially, what is causing the tinnitus. NO EFFORT. Nothing. Not even MRI referral. Just, "oh hai, good hearing, now leave!". The other, "uh, well, yeah! sorry this is happening to you!". You want me not to be hard on them? This condition has ruined my life, and my career. They didn't even try and that's why I hate ENTs. They didn't even say, "hearing loss", just... "DUNNO!". And didn't bother beyond that. I wouldn't feel as PISSED if they tried... oh I dunno doing their job? Maybe stick a camera up my nose, CAT/MRI, something? Nope, just a big eff you! Sorry, I guess since I don't have a serious condition, this isn't a big deal to ENTs, but it has ruined me. I barely feel human
       
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    16. Samir
      Obedient

      Samir Manager Staff Benefactor

      Location:
      Sweden
      Tinnitus Since:
      12/2016
      Cause of Tinnitus:
      Accoustic trauma
      You made me curious! What state or country were these students from?

      I don't think it's a niche topic. Regenerative medicine in all of its glory is a subject that has been widely discussed and fiercely debated in media. It is certainly not unheard of in the medical field or among professional researchers and educators.

      Some people maybe got stuck on discussing the ethics of using embryonic stem cells, and could not see past that. Some may be just out of the loop, not in touch with the latest developments in science and technology. Some may not have a pressing need to see these scientific advancements get a green light so they never bother reading the science section of the newspaper.

      Regardless! Regenerative medicine, and personalized medicine is the medicine of the 21 century! Biology students should have come in touch with regenerative medicine at some point, regardless of what their specialty is. But being a PhD candidate in otology and not knowing about these efforts to regenerate the hair cells is a bit surprising. But not as surprising as working in the field for the last 20 to 30 years and not knowing anything about it.
       
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    17. Samir
      Obedient

      Samir Manager Staff Benefactor

      Location:
      Sweden
      Tinnitus Since:
      12/2016
      Cause of Tinnitus:
      Accoustic trauma
      @RB2014, this is a pretty spectacular picture.

      155116_web.jpg

      "A stem cell-derived neuron grafted onto a mouse cochlea in the inner ear that lacked neurons. The new neuron is marked red, hair cells that convert sounds into neural signals are green, and hair bundles are blue."
       
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    18. Benoves

      Benoves Member Benefactor

      Tinnitus Since:
      26-9-2017
      Cause of Tinnitus:
      Unknow possibly noise trauma
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    19. Samir
      Obedient

      Samir Manager Staff Benefactor

      Location:
      Sweden
      Tinnitus Since:
      12/2016
      Cause of Tinnitus:
      Accoustic trauma
      That looks like another reason to be hopeful!

      With this company, we are now at 29 companies working towards reversing sensori-neural hearing loss.
       
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    20. Aaron123

      Aaron123 Member

      Tinnitus Since:
      00/0000
      Cause of Tinnitus:
      Irrelevant
      Here's the company's web page: https://ear-cell.com/

      There's not really any useful information, and at this point I am pretty skeptical. The "scientific articles" are a joke. In contrast to the Draper Laps pump, there's no information on the "FluidSync micropump".

      Maybe there is something there. Happy to be wrong, but I am not holding my breath.
       
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    21. Makrohn
      Supportive

      Makrohn Member Benefactor Advocate

      Location:
      Norway
      Tinnitus Since:
      1996
      Cause of Tinnitus:
      Hearing loss - Explosion - Stress
      Not to mention all the other medical companies working with different research that could lead to a breakthrough in e.g. hearing loss. I'm saying the focus should not entirely be on those who are doing research on the inner ear... There are numerous examples of meds being developed for one thing then ending up curing something completely different.

      And with all the research going on and how fast we are moving on, I am having a hard time believing we wont see a cure or relief within 10 years of time.
       
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    22. Jim51042

      Jim51042 Member

      Tinnitus Since:
      3/28/16
      Cause of Tinnitus:
      Headphone use
      Are these stem cells that convert into neurons the same stem cells that frequency uses to convert into hair cells? Would doing one procedure make the other less effective? If so what is more important for tinnitus many more neuron connections or new hair cells connections?

      https://newatlas.com/stem-cell-hearing-cancer-risk/52108/
       
      • Good Question Good Question x 1
    23. Aaron123

      Aaron123 Member

      Tinnitus Since:
      00/0000
      Cause of Tinnitus:
      Irrelevant
      No. The Song et al paper is doing something completely different and is very much basic science research.
       
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    24. Jim51042

      Jim51042 Member

      Tinnitus Since:
      3/28/16
      Cause of Tinnitus:
      Headphone use
      Thanks. Let's hope that they commercialize this soon.
       
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    25. Samir
      Obedient

      Samir Manager Staff Benefactor

      Location:
      Sweden
      Tinnitus Since:
      12/2016
      Cause of Tinnitus:
      Accoustic trauma
      Speaking of which...

       
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    26. Leo Pappas

      Leo Pappas Member

      Tinnitus Since:
      17/4/2016
      Cause of Tinnitus:
      Unknown
      If anyone is interested this video was just uploaded half an hour ago. Its by frequency inc. it said at the beginning of the video.

      How to Regenerate the Human Body: Hearing...
       
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    27. Aaron123

      Aaron123 Member

      Tinnitus Since:
      00/0000
      Cause of Tinnitus:
      Irrelevant
      It's a video of Chris Loose who is the Chief Scientific Officer at Frequency. There's no new information though he does clarify the difference between progenitor cells and stem cells which folks seem to confuse sometimes. You can see some more info about Chris Loose at http://bigthink.com/experts/chris-loose
       
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    28. Reinier
      Not amused

      Reinier Member Podcast Patron Benefactor

      Location:
      Netherlands
      Tinnitus Since:
      06/2015
      Cause of Tinnitus:
      Explosion starting engine
      I get the impression he is addressing the scare some people have that stem-cell therapies can turn into uncontrolled growth of cells.
       
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    29. Christian78
      Alone

      Christian78 Member

      Location:
      Gothenburg
      Tinnitus Since:
      (Sep 2013)
      Cause of Tinnitus:
      progressive tinnitus, time of expiring in next 3-6 months
      They can turn to uncontroled and after 10 years turn to tumors
       
    30. Reinier
      Not amused

      Reinier Member Podcast Patron Benefactor

      Location:
      Netherlands
      Tinnitus Since:
      06/2015
      Cause of Tinnitus:
      Explosion starting engine
      After 10 years? Has that happened?
       
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