Lenire — Bimodal Stimulation Treatment by Neuromod

The 10-15 year timeframe for drug treatment is, I think, a pessimistic timeframe.
Knowing that many companies are already well advanced in their trials.
10-15 years is the time it takes for a drug to be on the market from the discovery of the molecule. In our case the molecule(s) have been discovered for a long time.

But I agree on neuromodulation, I think it is the most promising treatment.

 

10 or 15 years? That is quite a pessimistic view. I am pretty sure it will be available before that.

 

What should we expect? - that they should publish the big trial they've been referring to for years now - they said they were about to publish in late 2018.

The % who worsen is such a critical decision for people in weighing up whether to get treatment - another reason they should not have started selling the device before trial publication.

We are very lucky to have PeterPan's report.

 

It's now handed over to the Tinnitus Talk team for branding etc (and I've finished with it!). There is a summary PowerPoint highlighting the main results (8 pages) and a detailed word report with all you should want to know (70 pages).

I've had a lot of fun putting it together and I hope it will be of value to the forum.

 

Thanks @PeterPan for all your work on this. You are truly and asset here at Tinnitus Talk. I can't wait to see the results and see how they correlate to Neuromod's numbers.

I am starting to think that there really is a placebo effect with their numbers and that is why perhaps we haven't seen the papers yet. Someone in this thread reached out to Susan Shore about Neuromod and she stated that you really have to be cognizant of the placebo effect with tinnitus. Seven point change in THI is considered clinically significant but that number for me would almost fluctuate daily. I have good days and bad days and my THI score could move around as much as 20 points.

Do I think Lenire will help some people, absolutely. I think I fell in the trap of thinking that it would help me since the numbers looked so good, but in reality even if I did get a seven point THI that really wouldn't do much for me and I failed to really look at the numbers and just saw this product as a way out of this. I do think neuromodulation has the potential to be helpful for this, but I think Susan Shore's product is going to be much better or possibly Frequency Therapeutics.

I will keep motoring on with my device and see if I get any improvement, though I am unable to get settings changed. I do regret a little bit taking the chance on Lenire, but I guess you never really know unless you try it.

 

Neuromod also be like this:

 

It’s been a while since I’ve been here. I have read some posts. All I can say is after 4 months of treatment, I never thought my hyperacusis would improve but thanks to Lenire it has.

You don’t have to criticize just by the numbers. You are ruining the decisions of people that might actually benefit from it, like me. If you don’t agree or like their service just don’t go for it, there’s no need to write bad stuff about it and influencing other people's decisions.

 

So you saw improvements only after you used Lenire for four months, is that correct?

 

Do you have pain or loudness hyperacusis?

 

Yes. You can read my previous posts. I started when I was getting to a really bad state, and I wasn’t even fully committed since I’ve been using it only 1 time per day. I should do it 2 times per day.

 

Both. Mostly loudness. Pain I'd say mild.

 

Has anyone agreed with Neuromod on remote assessment?

 

I had my 3rd review online with Neuromod on Tuesday. They organised for a courier (at their expense) to collect my device (which arrived in Ireland in 24 hours) and it is already on the way back to me.

Quite impressed with their customer service on this one.

 

So it's just when you are already their client, right? They don't do online assessments for new patients?

 

I think they considered it but since you have to do a hearing test it looks unlikely. But never say never.

 

Sounds good. So how has Lenire worked out for you in the long run?

 

Their hearing test is fairly standard - they do an audiogram, and a tinnitus loudness matching (they don't do tympanometry and other possibly damaging tests, mercifully). It would definitely be possible to get those done locally and just email them the results. So they can get this done if they want to.

 

I did not make any further progress with the 2nd settings. Because of the coronavirus I was not able to travel to Dublin and I decided to stop using it for the time being. I will start again next week with the first settings.

 

Anyone selling their device (setting 1, no sound compensation)?

 

My device has just safely returned

 

What is your general opinion of Lenire? How much has it helped you so far?

 

@alanisnotadj

Did the new noise you describe above fade for you?

Glad you got your device safely back.

 

It has reduced greatly but it has not gone 100%.

It worked quite well with the first settings. My tinnitus improved no doubt. But the second settings did nothing for me so I am glad that I can now start again with the first settings.

 

Anyone here who had temporary relief (tinnitus loudness went down) after taking Xanax and also benefited from Lenire?

 

Me.

 

I wonder if there isn't some correlation. Xanax might point to the neurological base of tinnitus which Neuromod's device can alter. I read though that these drugs lower brain nueroplasticity so it's better to stay off from them while using Lenire. On the other hand microdosing of some psychedelics increases neuroplasticity. Maybe Lenire + microdosing shrooms might be a more effective formula.

 

During my first, successful run with Lenire, I was on armodafinil at least every second day. It was for unrelated reasons (I was starting a new job and often didn't have enough time to sleep and I needed to eradicate fatigue), but it might have helped. Also, because of the new job, my brain was in "learning mode" all the time, that might have helped too.

 

Interesting. Maybe during Lenire session one should try to learn something. New language, knitting, ... Might sound funny but who knows.

Some visual part can come into play as well, perhaps also hypnosis. These are ideas for new studies. Multifactorial tinnitus treatment.

 

Never heard of that and I've just read up on it on the NHS website - good lord, that sounds bad. Maybe there is something worse than tinnitus...