Levetiracetam (Keppra) — Another Possible Potassium Channel Modulator?

Discussion in 'Research News' started by Viking, Dec 15, 2014.

    1. gintas

      gintas Member

      Location:
      Lithuania
      Tinnitus Since:
      2015-05
      and it is working ? because early you said that you are using keppra 500mg X2 a day ?
       
    2. Danny Boy
      Cheerful

      Danny Boy Member Benefactor Hall of Fame

      Location:
      England
      Tinnitus Since:
      7/2014
      Cause of Tinnitus:
      Ear infection
      I use 2000 a day.
       
    3. gintas

      gintas Member

      Location:
      Lithuania
      Tinnitus Since:
      2015-05
      when it can began to work ? how many days it can to take ? maybe i will use it .,p.s. and you now didnt using it ? and H is gone ?
       
    4. Lloyd Carter
      Wishful

      Lloyd Carter Member

      Location:
      United States
      Tinnitus Since:
      August 2015
      Cause of Tinnitus:
      Noise Induced Trauma
      @nills @Danny Boy The thing I'm worried about is work. I need to drive and work. Is is possible to do the Trobalt experiment without losing the ability to do these two things? Also, @Danny Boy why did Trobalt cure once off the drug? Could the T come back if you went off Keppra? So happy you've found relief!
       
    5. nills
      Barefooter

      nills Member Benefactor

      Location:
      Belgium
      Tinnitus Since:
      11/2009
      Cause of Tinnitus:
      acoustic trauma
      I don`t know much you need to drive. if you drive taxi I think you shouldn`t use it. If you drive some machine like forklift also not. If you can space your driving around your pills it`s ok.. the first hour after the pill hits is the worst ... after that it should be quit ok. But If I would think of driving while I had my `trobalt fits` I would definitely have had a tricky situation. It is dangeorus in those moments. It`s not just being a little high or a little bit drunk ... sometimes Trobalt seems to shut down parts of the brain and your just left stupid and incoherent for a little while.
       
      • Agree Agree x 1
    6. Lloyd Carter
      Wishful

      Lloyd Carter Member

      Location:
      United States
      Tinnitus Since:
      August 2015
      Cause of Tinnitus:
      Noise Induced Trauma
      @nills You said you regretted not taking trobalt earlier. Do you think people with mild T should try it? I can't really hear mine unless I'm in a quiet room.
       
    7. canyonero

      canyonero Member

      Location:
      Eastern US
      Tinnitus Since:
      7/2014
      Cause of Tinnitus:
      Acoustic Trauma?
      Has this worked for anyone besides Dannyboy?
       
    8. Danny Boy
      Cheerful

      Danny Boy Member Benefactor Hall of Fame

      Location:
      England
      Tinnitus Since:
      7/2014
      Cause of Tinnitus:
      Ear infection
      It's worked for MPT.
       
    9. Karl28
      No Mood

      Karl28 Member

      Location:
      Melbourne
      Tinnitus Since:
      2001 bad since 2015
      Cause of Tinnitus:
      Loud music via headphones
      What do you do for work?
       
    10. lapidus

      lapidus Member Benefactor

      Location:
      Sweden
      Tinnitus Since:
      1999
      Cause of Tinnitus:
      Noise induced
      This is the Keppra thread. MPT never took Keppra.
       
    11. Danny Boy
      Cheerful

      Danny Boy Member Benefactor Hall of Fame

      Location:
      England
      Tinnitus Since:
      7/2014
      Cause of Tinnitus:
      Ear infection
      Oh, sorry!
       
    12. Lloyd Carter
      Wishful

      Lloyd Carter Member

      Location:
      United States
      Tinnitus Since:
      August 2015
      Cause of Tinnitus:
      Noise Induced Trauma
      @Danny Boy , do you mind telling us why you were able to stop Trobalt but must continue with Keppra? Why would Trobalt have a permanent effect and Keppra not?
       
      • Like Like x 1
    13. Danny Boy
      Cheerful

      Danny Boy Member Benefactor Hall of Fame

      Location:
      England
      Tinnitus Since:
      7/2014
      Cause of Tinnitus:
      Ear infection
      Because keppra is a safe drug compared to trobalt. Also keppra inhabits KV3.1 channels, doesn't open them. Trobalt worked because it opens channels, keppra doesn't. Although some report a 30% decrease using keppra. I can't give you a definite answer. I would just try keppra first, as trobalt isn't the safest drug sadly.
       
    14. RaZaH
      Cheeky

      RaZaH Member Benefactor Hall of Fame

      Location:
      Reykjavík, Iceland
      Tinnitus Since:
      2012/04
      Cause of Tinnitus:
      Benzo + loud noise
      So, @Danny Boy would you say that if one were to try a drug , one should try Keppra rather than Trobalt ?
       
    15. Danny Boy
      Cheerful

      Danny Boy Member Benefactor Hall of Fame

      Location:
      England
      Tinnitus Since:
      7/2014
      Cause of Tinnitus:
      Ear infection
      I would say keppra as it's safe compared to trobalt.
       
    16. Lloyd Carter
      Wishful

      Lloyd Carter Member

      Location:
      United States
      Tinnitus Since:
      August 2015
      Cause of Tinnitus:
      Noise Induced Trauma
      @Danny Boy Even if the problem is just T and not H? How can Keppra be bought?
       
    17. Lloyd Carter
      Wishful

      Lloyd Carter Member

      Location:
      United States
      Tinnitus Since:
      August 2015
      Cause of Tinnitus:
      Noise Induced Trauma
      And @Danny Boy how do you know Trobalt cured T if you're still on Keppra? Couldn't it possibly come back if you stopped the Keppra? Thank you so much for being so informative!
       
    18. Danny Boy
      Cheerful

      Danny Boy Member Benefactor Hall of Fame

      Location:
      England
      Tinnitus Since:
      7/2014
      Cause of Tinnitus:
      Ear infection
      Possibly Mexico? Or a doctor has to prescribe it.
       
    19. Lloyd Carter
      Wishful

      Lloyd Carter Member

      Location:
      United States
      Tinnitus Since:
      August 2015
      Cause of Tinnitus:
      Noise Induced Trauma
      @Danny Boy Thanks! Do you mind answering my other two questions (I know it's a lot!)

      1) Would you say Keppra can bring down T and not just H?
      2) How do you know Trobalt cured T if you're still on Keppra? Couldn't T possibly come back if you stopped Keppra?

      I'm interested in why Trobalt could be a permanent cure and not Keppra.

      Thanks again!
       
    20. Danny Boy
      Cheerful

      Danny Boy Member Benefactor Hall of Fame

      Location:
      England
      Tinnitus Since:
      7/2014
      Cause of Tinnitus:
      Ear infection
      1. I can't answer keppra as I mixed them both, so have no idea.
      2. I highly doubt keppra is ensuring total silence, but hey, who knows?
       
    21. Lloyd Carter
      Wishful

      Lloyd Carter Member

      Location:
      United States
      Tinnitus Since:
      August 2015
      Cause of Tinnitus:
      Noise Induced Trauma
    22. Danny Boy
      Cheerful

      Danny Boy Member Benefactor Hall of Fame

      Location:
      England
      Tinnitus Since:
      7/2014
      Cause of Tinnitus:
      Ear infection
      Because I might as well use the supply up.
       
    23. Lloyd Carter
      Wishful

      Lloyd Carter Member

      Location:
      United States
      Tinnitus Since:
      August 2015
      Cause of Tinnitus:
      Noise Induced Trauma
      @Danny Boy Good answer! Are you nervous at all about having issues once you're done with it?
       
    24. Danny Boy
      Cheerful

      Danny Boy Member Benefactor Hall of Fame

      Location:
      England
      Tinnitus Since:
      7/2014
      Cause of Tinnitus:
      Ear infection
      Well, if it comes back, it comes back. There's nothing I can do. I don't think it'll ever go back to baseline though.
       
      • Agree Agree x 1
    25. Lloyd Carter
      Wishful

      Lloyd Carter Member

      Location:
      United States
      Tinnitus Since:
      August 2015
      Cause of Tinnitus:
      Noise Induced Trauma
      @Danny Boy Praying for you to stay with total silence. Hopefully they'll keep playing around with these potassium modulators and we'll all be cured in the next decade! Fingers crossed for Aut and SF! Thanks SO much for the informative responses!
       
    26. Danny Boy
      Cheerful

      Danny Boy Member Benefactor Hall of Fame

      Location:
      England
      Tinnitus Since:
      7/2014
      Cause of Tinnitus:
      Ear infection
      No worries! Thanks for the support. And if you have any more questions, just ask.
       
      • Like Like x 1
    27. Harvest King
      Studious

      Harvest King Member

      Location:
      Melbourne
      Tinnitus Since:
      2006
      I'm sorry to say it, but Keppra does NOT reduce tinnitus but it doesn't cause tinnitus either, so to speak.
      It is a broad spectrum stabilizer of electrical impulses with very few side effects which makes it an
      ideal anticonvulsant.
      Potassium channels exist to stabilize electrical activity coming from neurotransmitters. However because of the
      brain's elasticity, prolonged use of Keppra will cause the reduction of the need for potassium channel activity.

      The neurotransmitters actively stimulating the cochlear nerve need to be specifically targeted.
      My own research leads me to believe that there exists an involuntary neurotransmission, call it an electrical handshake between the brain, the various nerve centers and associated senses.
      When there is no response . . . . say temporary or minor damage to the cilia for instance from a variety causes, the electrical activity increases to achieve a response.
      That is why tinnitus slowly increases over time.

      Of course there is a lot more I can say regarding this matter but I am still actively researching my hypothesis.

      It sounds as if there is no hope BUT you can only fix something when you know what is causing the problem.

      Cheers

      Harvest King
       
      • Informative Informative x 2
      • Like Like x 1
      • Helpful Helpful x 1
    28. amandine

      amandine Member

      Tinnitus Since:
      july 2014
      No Keppra did not cure Danny's T.....he says that Keppra cured his H and sound reactiveness. His T sadly remains in spite of the huge amounts of Trobalt that he has / is consuming. Bless him for all his efforts with this.
       
    29. skoupidis

      skoupidis Member

      Tinnitus Since:
      09/2014
      Cause of Tinnitus:
      Acoustic trauma or mvc
      Yes, suffice it to say that neither Keppra nor Trobalt cures Tinnitus, Danny did take a lot of those...
      I am talking about cure, not temporary effects.

      My experience with Keppra ended up inconclusive: I do have a really flaxuating T, from 2 to 9 depending on days and God knows what else, so I doubt I would even understand the effects of Trobalt if I tried it.
       
      • Hug Hug x 1
    30. Dutchy
      Not worthy

      Dutchy Member Benefactor

      Location:
      Netherlands
      Tinnitus Since:
      12/2014
      Cause of Tinnitus:
      Neuronmodulation suggests noise induced?

      It's great to see his H resided.On a personal note though,my T is pretty mild i guess but i already am very cautious now about the noises surrounding me.No more loud music,avoiding loud crowds and i'm going to fit custom earplugs
      for working situations. Edit: I'm not very keen about trying meds without too much knowledge as penicillin poisoning nearly killed me as an infant.
       
      • Funny Funny x 1
Loading...
Similar Threads - Levetiracetam (Keppra) —
  1. Danny Boy
    Replies:
    793
    Views:
    93,914

Share This Page