My Posting Place

I have NAC, but which one brand promotes the best variation of it?

 

So it’s NAC?

 

Kinda looks like the hough ear pill is for acute cases?

 

I think it's a combination of NAC and something called Disufenton.
Other names:
Disufenton/N-acetylcysteine
HPN-07/NAC
NHPN-1010
NXY-059/NAC

 

McKenna et al even wrote that a) people only think their tinnitus is loud when it actually isn't and that b) people distressed by their tinnitus could learn to be less aware of it if they stopped evaluating it negatively. Tell me again how mindfulness research isn't holding back real medical treatments for tinnitus. Perhaps they don't even see the need for medical treatments because they're seemingly convinced whether someone suffers from tinnitus or not has nothing to do with their type of tinnitus and, therefore, loudness doesn't matter and doesn't need to be reduced. At least that's my impression.

• If therapy reduces a patient’s negative thoughts about tinnitus, then there will be less arousal and less distress and this in turn will lead to less selective attention and monitoring. Tinnitus will, therefore, be less prominent in the person’s life as the person will attend to it less.
• It is proposed that negative evaluation, and in particular negative images of tinnitus (e.g., it sounds like a drill; it sounds unnatural) also lead to overestimation.
• The possibility that perception may be distorted was first mooted by Fowler (99), who suggested that patients with tinnitus “experience an exaggerated sensation as to both its loudness and its timbre, and it is then overestimated and sensed as a most disagreeable or unbearable noise” (p. 396).
• This suggests that people’s self-reports overestimate the “true” loudness of tinnitus as measured by conventional matching techniques.
• Andersson and Kaldo (147) suggest that “it is important to work toward acceptance of tinnitus and to foster the idea that tinnitus is not worth the attention it gets” (p. 99). This would seem to be a difficult thing to achieve if tinnitus really is, or the patient continues to believe that tinnitus is, of the intensity of, say, a jet engine.

EDIT: I just don't think that their concept represents the whole tinnitus spectrum. They seem to invalidate every case that doesn't fit their model.

 

"NHPN-1010 is a combination of known therapies HPN-07 (2,4-disulfonyl α-phenyl tertiary butyl nitrone) and N-acetylcysteine (NAC). The latter is approved for intravenous use in liver toxicity (such as can be caused by acetaminophen)."

http://www.bioworld.com/content/ser...pharmaceuticals-hearing-loss-pill-path-clinic

Oy!

 

Triggered

 

Very expensive:

$50 for 5mg.

https://www.sigmaaldrich.com/catalog/product/sigma/sml2163?lang=en&region=US

 

Disufenton other names:

 

JA, I am fascinated by this company too, did you read up on their regenerative therapies? Where did these guys come from? My impression is they are doing really good work... strange that they finally show up now on this forum. The pill, I had the impression was for soldiers, with bomb blasts... What do you think about their regenerative therapies with mice? I wish all of these scientists and doctors would communicate more... would sure help.

 

I honestly don't have a clue about their hair cell regeneration tech. My best guess is that they have another notch1 inhibitor drug.

There is a cellular signaling pathway called notch. In mammals there is notch1, notch2, notch3, and notch4. Regenerating hair cells seems to begin when the notch1 receptor is inhibited, do some googling. There are many molecules discovered thus far that can achieve this.

 

@threefirefour thanks for liking my comments on basically figuring out the Hough Ear Institute's recipe for an oral tinnitus drug. At least someone gives a fuck.

 

I spent a good hour today looking up this Disufenton drug and seeing if there are any natural things that do the same thing. Sadly, I could not find anything that we can buy as a supplement to mimic this. That doesn't mean there isn't one and the rest of you need to be researching with me. It looks like it's NAC on steroids, I just don't know. I would greatly appreciate some parallel research. This isn't for me, it's for all of us.

 

It perplexes me why JA believes God exists. Not very scientific

 

Stop flirting with John where we can all see you, it's embarrassing.

 

As long as he thinks h's going to Hell where he belongs it's cool.

 

I'll help.

 

Oh he got him

 

It perplexes you because you are ignorant. You think you've seen all the evidence that's out there but you havent.

Read the whole Bible and get back to me.

 

misdiagnose city.

 

He eats them for breakfast

 

Laughing my wrinkly ass off.

 

When somebody makes a habituation post on the success stories forum

 

tfw I quit MPP because it's not going to get our cause anywhere.

 

It's more like a meeting ground for the community. It's uphill so far but we're all working on stuff. You're taking out scammers and I'm converting other tinnitus forums. And people like IamCalifornia and JohnAdams are experimenting themselves. Honestly I didn't think MPP would be productive whatsoever but here we are.

 

what im saying is moving on outside the forum is better then staying on the forum.