My Posting Place

Johnny boy time to ignore you!

 

Hey Y'all, I'm very much alive! Like @Daniel Lion said I've been out riding, met a girl, and have been working a lot.
My tinnitus has mostly been at the back of the bus. Over the last 2 months I've had 3 or 4 very bad days. I feel blessed that this has happened to me as my relentless mega high pitch tinnitus is lower but also bothers me WAY less now. For the newbies here I've had Tinnitus for over 2.5 years now.

@Jack Straw Thanks for your concern man, I still log in here everyday but now that Lenire has released I'm just checking in on that and also excited! It feels like there might be a light at the end of the tunnel!

Hope everyone is doing well!

 

You don't like tendies?

 

@PDodge If you could see my face I am smiling you responded. Send this to a success story!

 

Good for you man. I'm happy for you, and also jealous. Hope Lenire might help me and all of us.

 

Seriously though, check these things out.

 

looks delish

 

I think there are 5 types of tinnitus:
1. Mechanical induced neuro-dysfunctional tinnitus
- TMJ
- cervical
- etc.
2. Neuropathic induced neuro-dysfunctional tinnitus
- auditory nerve damage
- synapse damage
3. Non-cochlear stimulus deprivation induced tinnitus
-Earwax blockage
-Glue ear blockage
-middle ear bone defects, damage
- tympanic membrane dysfunction, damage, perforation
4. Cochlear stimulus deprivation induced tinnitus
- loss of the hair cell
5. Auditory cortex damage induced tinnitus
- damage to the auditory cortex.

The presence of tinnitus is not limited to any single one of these etiologies. There's your subtypes.

A pure tonal hearing test combined with a speech in noise test should be able to help distinguish between 2 and 4 in some cases. The rest should be able to be diagnosed with an ear exam or an MRI or fMRI.

Anyone care to elaborate on this?

 

Loss of stereocillia alone does not produce tinnitus, (peripheral) neuropathy does, so point 4 is not accurate. That's also why some people suffer from hearing loss, yet don't get tinnitus. As long as the nerve endings aren't damaged, the auditory cortex doesn't produce the "phantom sound", even if the frequency isn't perceived by the cochlear.

 

Okay. So then in the instances of hair cell loss, you think the tinnitus signal is generated by accompanying nerve damage in every case? I am open to this.

However, this would go against the experiments showing using earplugs can generate tinnitus. Also, earwax buildup can cause tinnitus as well. So wouldn't that mean that simply losing input can generate tinnitus and therefore mean that also just losing the hair cell could also generate tinnitus?

 

Indeed, neuropathy always induces some form of hearing loss (hidden or otherwise), and is usually accompanied by the death of its attached stereocillia, the death of a stereocillia on the other end, does not always induce neuropathy, while both cause hearing loss, neuropathy causes tinnitus.

Neuropathy can also be caused from chronic noise exposure. (As well as many other possible causes, such as acute noise trauma, inner ear infections, ototoxic medications....) this is why the line between people suffering from hearing loss but not tinnitus, and tinnitus sufferer is often blurry and misunderstood, recent biopsies however have shown a very clear correlation between neuropathy and tinnitus.

So to cure tinnitus, one would need to heal/regenerate the peripheral nerve. I do not know how successful the drugs currently undertaking clinical trials are at doing so.

 

The thing is earplugs and earwax do not cause tinnitus per se, rather they increase the perception of an already existing underlying condition (tinnitus), which already existed in those individuals (typically from pre-existing nerve damage), in fact, losing input does not cause stereocillia's death, it does however trigger the auditory cortex into increasing its "gain" which makes everything, including an existing tinnitus, sound much louder (and can cause hyperacusis), the once unnoticed tinnitus is then percieved and the individual then focusses on it, which increases stress, which triggers a negative feedback loop which further increases the perception of tinnitus, which makes the auditory cortex focus/tune to it and so on.

Tinnitus perception itself is very complex and relies on multiple factors, the cause however is more often than not, peripheral neuropathy.

 

I don't think any are currently going through trials. Otonomy plans to begin trials for BDNF this year.

 

Do you really think PTA test is that much powerful?

I don't really know. But even researchers nowadays say that PTA is not reliable. E.g. it can't show hidden HL but an ABR test (they say) in case of HHL is more reliable. Despite all these things I think there is no method to guarantee that your hearing is 100% fine. I guess one can evaluate his hearing better than a PTA can. For example you go to an audiologist and describe your problems and he tests your hearing(lets say UHF test) and say you're ok, goodbye :| literally saying, I don't really know if we should trust them.

 

TRT = Tender Roasted Tendies

 

@JohnAdams - How about adding #6 long standing/over the top stress that triggered my T. In other words a mini snap. And throw in dental work at the same time also did something. My T is not from hearing. So, I would add #6 to your list. Not everyone fits in the top 5.

 

Yeah I also forgot to add ototoxic damage. ewps.

When under stress, your body produced cortisol and that stuff is damaging to body tissues so maybe that falls under ototoxicity maybe?

 

@fourfrostfive

 

Body produced cortisol could be, I was having a difficult mental experience plus a root canal was done months back then the crown was put on pain, I had them take off crown put on temp which is still on, To me it was a mental stress snap T.

 

I want to welcome all the new TT members that will be joining us in July 5th.

 

tomorrow...

 

more like you just casually stand up and go inside and cry.

 

When I think of them I wanna call them those idiots but you know we would do the same if we were in their shoes.

 

This isn't the actual reality, r-right guys

 

Hi guys, I'm just curious to know what would happen if someone with a healthy auditory system get FX-322 or other regenerative drugs? Would they end up with too many hair cells and possibly become super humans?

I mean what would they do if they couldn't find any hearing loss with the current tests like PTA? But the patient still has tinnitus.

 

Sorry for bothering you good people all over again, but I need advice from MPP members once again. I am really close to suicide today and considering doing it fast so I think it's a good time to write to you all a message. My situation just keeps getting worse. My sister lied and slandered me to my other sister who lives in London to the point I don't know if my other sister and her kids will want to have anything to do with me. Also, my sisters' kids have written me horrible messages calling me a pig, a fat loser and similar insults. Also, my mother was not only verbally saying that she wished I would die, but has used physical violence against me. What to do in this situation, my mother lives in the same house as I do so I can't get away from it or escape especially now that I am financially dependent on her. I can and have separated from my sister, but it doesn't seem to be enough since she continues to mock and terrorize me.

I honestly just don't see any other way out of my situation, but suicide. I never thought that at my darkest hour of need then I am in the weakest position I ever been in my family would treat me this way it's just so cruel and inhumane. I used to be a happy, confident, healthy and strong person then I was all of that my family at least respected me a little as a person and as a provider that gives them income, now that I am a broken shell of my former self unemployed and living on disability all of that seems to be gone.

As far as my hearing problems go my hyperacusis is entirely gone for some time now so that is not a big problem for me. My tinnitus has gone from moderate to mild in the last few years so I can live with it. But my hidden hearing loss (cochlear synaptopathy) is just horrible, I can't hear anything then there is background noise, music sounds distorted, I can't hear the dialog on my favorite TV shows and movies, I barely hear a person sitting next to me in a silent room so basically I can't function like a normal person add a psychological problems of mine and yes I am suffering and having a hard time.

News about my NR experiment it does seem to somewhat help my tinnitus and makes it, even more, milder, I now only hear it at night in complete silence but I see no improvement in my hearing so far maybe it's still too early for any effect to take place since most of the forum that did get improvement from it said that they took it at least a month.

 

Man, I'm so sorry to hear about your situation.

We need our families support, and it sounds clearly like they are not on your side and are destructive.

Few ideas...

Have your mom and sisters watch the Gaby Olthuis, Dutch suicide lady video. Have them watch Jazzer's video and a few others in the awareness section. Maybe they can get educated.

If you have a sympathetic extended family member or friends who have a spare room... move out.
Try and be polite and loving... but walk away from fights... the stress is a killer and will ramp up your tinnitus and hyperacusis.

I wish I was near you man, I’d have a word with your family... but I am not.

You need to take care of your physical and mental health now... avoid confrontation... lie if you have to... and slowly plan an exit strategy.

Really sympathize and am sorry you have to deal with such cruelty... life is truly unfair.
Be strong... be calculating... avoid fighting... and be smarter than everyone around you and universe willing you will find a way out.

Don’t do the suicide thing... it’s natural to contemplate... everybody here does... I do far too often...

Hang tight... get physically strong, eat right... and plan your escape....

May the force be with you.

 

Dude, I don't know what to say, I don't really know, due to some problems right now I'm as suicidal as I've never been before but hang in there man.

I know that there are lots of things I haven't done in my life, when I think about suicide deeply and it's methods I really cry because I don't wanna die. I want to play and experience more. I try to stay positive that if there is only 1% possibility that things will get better they will definitely get better.

I'm sure that there is still things or people in life which mean a lot to you.

A bright day will come just hang in there.

 

"Suicide is a permanent solution to a temporary problem" Often those words are not true, as the problem is a permanent one. However, it seems to me that in your case the above is actually true - your problem is temporary. You have had a serious fight with your close relatives, but people change. Also surely in the long run you don't have to be around those people. Right?

Even your hearing loss might be reversible - there are possible treatments on the horizon now.

I sincerely hope that you don't do anything under the influence of the sadness you have experienced as a result of a fight (the kind that happen in most relationships).

Consider giving it a year. If you still feel that way in a year, then it would make more sense to do it...

What's that?