New University of Michigan Tinnitus Discovery — Signal Timing
- Thread starter Hudson
- Start date
Member
It's not. It's linked from a UMich newsletter I just received on May 29th. The email stated the following:
The post on their LinkedIn describes them as a "licensee of bimodal patents" to a number of companies. I imagine this has been discussed before, but it suggests to me that instead of developing its own products entirely in-house, the company is licensing these patents to others who are working on devices aimed at the same goals as the Susan Shore device and its underlying research.
To me, this means that multiple firms may be developing similar tools or treatments, which could increase the chances of effective solutions reaching the market. Since the patent licensing covers such a broad range, it may also explain why it is difficult to get specific information directly from Auricle.
Again, this has likely been mentioned before, but in my view, it is encouraging. It suggests that other companies are also working toward the same goal of effective treatment.
To me, this means that multiple firms may be developing similar tools or treatments, which could increase the chances of effective solutions reaching the market. Since the patent licensing covers such a broad range, it may also explain why it is difficult to get specific information directly from Auricle.
Again, this has likely been mentioned before, but in my view, it is encouraging. It suggests that other companies are also working toward the same goal of effective treatment.
NBB Seminar Series
Tuesday, June 17th, 2025 at 11:00am
The seminar will be In-Person.
Susan Shore, Ph.D.
Professor Emerita of Otolaryngology, Physiology, & Biomedical Engineering, University of Michigan
"Reversing pathological neural plasticity to treat tinnitus"
Abstract:The dorsal cochlear nucleus is the first site of multisensory convergence in mammalian auditory pathways. Principal output neurons, the fusiform cells, integrate auditory nerve inputs from the cochlea with somatosensory inputs from the head and neck. After noise exposure, fusiform cells exhibit increased spontaneous activity and cross-unit synchrony, physiological correlates of tinnitus. Underlying mechanisms include homeostatic and timing-dependent plasticity. To reverse the pathological plasticity, we delivered repeated bisensory auditory-somatosensory stimulation to guinea pigs with tinnitus, choosing an inter stimulus interval known to induce long-term depression (LTD). The LTD inducing bisensory (but not unimodal auditory) stimulation reduced physiological and behavioral evidence of tinnitus in the guinea pigs. Next, we applied the same bisensory treatment to human subjects with tinnitus using a double-blinded, sham-controlled, crossover study. The LTD inducing bisensory stimulation reduced both tinnitus loudness and intrusiveness. Unimodal auditory stimulation did not deliver either benefit. Bisensory auditory-somatosensory stimulation that induces LTD in the dorsal cochlear nucleus may hold promise for suppressing chronic tinnitus, which reduces quality of life for millions of tinnitus sufferers worldwide.
Herklotz Conference Room
300 Qureshey Research LabIrvine
- Oct 31, 2020
- 1,324
- Tinnitus Since
- 9-17-2020
- Cause of Tinnitus
- turning everything up to 11
Meyer37
Member
- Feb 10, 2025
- 11
- Tinnitus Since
- 2017
- Cause of Tinnitus
- faultyfire alarms going off repeatedly in apartment building
Seeing Christopher in your profile picture reminds me of Phil Leotardo, who also wore a neck brace, and how poor posture has worsened the intensity of my tinnitus. A good reminder to focus on posture!UC Irvine is just a little bit farther from the University of Michigan.
Is anyone planning to attend the seminar in person? It seems like a fantastic and rare opportunity to learn more about the current status of tinnitus research and the Shore Device.
- Oct 31, 2020
- 1,324
- Tinnitus Since
- 9-17-2020
- Cause of Tinnitus
- turning everything up to 11
I would attend, but it appears Dr. Shore and I have swapped living locations...
Ken219
Member
Read the abstract. It is vague and uses the word "may." Nothing sounds promising.If anyone out there is local to UC Irvine and can get to the Dr. Susan Shore seminar tomorrow, that would be great! Unfortunately, no recording will be made available...
- Sep 8, 2022
- 60
- Tinnitus Since
- 11/2020
- Cause of Tinnitus
- loud noise/construction
This is not ideal, but academic language is much more restrained than advertising or everyday speech. Advertisers tend to exaggerate, and in casual conversation we often draw conclusions that would frustrate most academics.
Dr. Shore only has a few studies that provide evidence that this may alleviate the symptoms of tinnitus. Good academics are trained to constantly question their own results.
I am definitely biased in favor of Dr. Shore because I hope this will work, but unless something significant happens in her talk, I am not ready to give up cautious hope.
The last couple of trials showed clear efficacy, and her results have been reproduced at least once. This method definitely seems to work for somatosensory tinnitus.
What I do not understand is why it still has not been tested on non-somatic tinnitus, which makes up roughly half of us. How hard would it be to include a few non-somatic participants in a trial?
withintention
Member
- Nov 26, 2023
- 107
- Tinnitus Since
- 10/2023
- Cause of Tinnitus
- Noise and/or infection
I have a theory on why Auricle is delayed.
I recently visited a new audiologist to establish care and discuss hearing aids for masking.
Two audiologists greeted me and introduced me to a representative from Lenire. The three of them then spent an hour delivering what felt like a scripted hard sell for Lenire. I am talking about sales tactics that resembled those used by timeshare salespeople. When I asked about hearing aids, their only response was, "Why don't you want to try the only FDA-approved device for tinnitus, Lenire?"
I have experienced less aggressive sales tactics when buying used cars. It became very clear that Lenire has a strong sales incentive program in place.
If Lenire has already partnered with many private practice audiologists in this way, then Auricle faces a serious sales and distribution challenge. They will need to displace Lenire in all of these existing relationships, which will be difficult given Lenire's first-mover advantage.
Auricle might obtain FDA approval but still struggle to establish a sales and distribution network because Lenire has already secured a strong foothold.
I recently visited a new audiologist to establish care and discuss hearing aids for masking.
Two audiologists greeted me and introduced me to a representative from Lenire. The three of them then spent an hour delivering what felt like a scripted hard sell for Lenire. I am talking about sales tactics that resembled those used by timeshare salespeople. When I asked about hearing aids, their only response was, "Why don't you want to try the only FDA-approved device for tinnitus, Lenire?"
I have experienced less aggressive sales tactics when buying used cars. It became very clear that Lenire has a strong sales incentive program in place.
If Lenire has already partnered with many private practice audiologists in this way, then Auricle faces a serious sales and distribution challenge. They will need to displace Lenire in all of these existing relationships, which will be difficult given Lenire's first-mover advantage.
Auricle might obtain FDA approval but still struggle to establish a sales and distribution network because Lenire has already secured a strong foothold.
- Jan 16, 2020
- 542
- Tinnitus Since
- 1992
- Cause of Tinnitus
- noise? infection? negative stress? other?
Now all Lenire needs is to introduce an after-sales follow-up, a heavy-duty persuasion session to convince the patient that their tinnitus has been cured. Like, no one can hear it... it is all in the mind.
Just kidding.
That said, I must confess that I benefited from TRT treatment back in the mid-1990s, although the ringing continued.
Sadly, my tinnitus has worsened. Maybe it is both age-related and noise-related, or perhaps it is due to my sensitive hearing.
withintention
Member
- Nov 26, 2023
- 107
- Tinnitus Since
- 10/2023
- Cause of Tinnitus
- Noise and/or infection
I forgot to mention this earlier, but the Lenire representative actually told me that the increase in my tinnitus after my acoustic trauma two years ago was psychosomatic, simply because I had very mild tinnitus before it. This, despite the fact that I could barely hear it in a quiet room back then and now I can hear it over a crashing waterfall. They were despicable.
I am glad to hear that TRT has worked for you, though I am sorry your tinnitus has worsened. I have found some small relief from playing distracting sounds and am interested in trying it more seriously. It seems to help extend the periods when I am not so focused on the ringing.
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