Scientists Manipulate Plasticity Mechanism in DCN

Discussion in 'Research News' started by Stephen Hill, Dec 15, 2015.

    1. Stephen Hill

      Stephen Hill Member Benefactor

      Tinnitus Since:
      December 2014
      Cause of Tinnitus:
      Noise exposure
      I can't say I fully understand it, but this research from August this year by several leaders in the tinnitus field is certainly interesting. Building on Susan Shore's earlier research, it seems they have been able to successfully manipulate (in the lab) the plasticity mechanism in the Dorsal Cochlear Nucleus, which is believed to be a strong component of T. Clever stuff :) Whether it would work in us humans is, of course, another matter. They're taking it to the mice next.
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    2. Jae

      Jae Member

      Tinnitus Since:
      I just love reading news about research development. At this rate, cure by 2020.
      • Optimistic Optimistic x 4
      • Agree Agree x 2
      • Like Like x 1
    3. Nucleo

      Nucleo Member Benefactor

      Tinnitus Since:
      This is basically a paper about TENS paired with tones. Not exactly new.
    4. @Nucleo do you know where else has this been done? Or are you saying that tones and TENS individually are not new?
    5. Nucleo

      Nucleo Member Benefactor

      Tinnitus Since:
      Tones paired with nerve stimulation have been used conjointly in the past, without much success. TENS devices in general are not being able to stimulate the required nerves relevant to tinnitus activity.

      There is a clinical trial going on right now:

      The most novel thing about this paper is that they are looking at the DCN, and the possible involvement of somatosensory nerves.
      • Like Like x 1
    6. Nick Pyzik

      Nick Pyzik Member

      Tinnitus Since:
      Cause of Tinnitus:
      Listening to in-ear headphones & playing in a band
      I found this article today. The way I read it, for people who think their tinnitus has disappeared over time, it's still there but the frontal lobe of their brain begins to be used more to compensate for this issue. What do you guys think?
    7. Cheza

      Cheza Member Benefactor

      Tinnitus Since:
      Cause of Tinnitus:
      Barking dogs/stress
      @Nick Pyzik
      From the article:
      This looks like something which correlates with the Back to Silence method espoused by @I who love music. The BTS method is a form of training whereby we label our emotional reactions, which I suppose labeling things is a function of the frontal lobe. In other words, the emotion is seated in the amygdala, but the frontal lobe assesses the emotion. Thus, the more we use the frontal lobe instead of being held hostage by the amygdala, the more tinnitus retreats into the background.

      I really don't know. I'm just surmising. As for myself, I've been trying the BTS method for months and it hasn't made much difference with me. If it's loud, it's loud. If it's mild, it's mild. My tinnitus does whatever it wants and I seem to be unable to influence it whatsoever.
      • Agree Agree x 3
    8. monacco

      monacco Member

      forte Antoine .monaco
      Tinnitus Since:
      Cause of Tinnitus:
      we can never habituate loud T
      • Agree Agree x 1
    9. dan

      dan Member

      Tinnitus Since:
      Forget Dr.Shore.

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