Sensory Hair Cells Regenerated in Mammal Ear

Discussion in 'Research News' started by Waldo Bracamontes, Jan 10, 2013.

    1. Nucleo

      Nucleo Member Benefactor

      Tinnitus Since:
      02/2011
      A year is an extremely short time in life science research. Expect the next breakthrough in 5-10 years.
       
    2. Ecip

      Ecip Member

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      Edmonton, AB/Switzerland
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      4.11.2015
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      Still unknown... possibly noise exposure?
      Its quite ridiculous. If even a quarter of the money spent on war and killing people was spent on research, a cure or easy treatment would of probably already been found.
      And if only corporations et al would quit being so damn greedy....
       
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    3. JohnK
      Busy

      JohnK Member

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      SF Bay Area
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      10/26/2015 (habituated) 5/13/2019
      Cause of Tinnitus:
      Doxycycline (2015) Otimize ear drops [neomycin] (2019)
      Well, war has generated a huge number of people with tinnitus, so there's that...
       
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    4. Ecip

      Ecip Member

      Location:
      Edmonton, AB/Switzerland
      Tinnitus Since:
      4.11.2015
      Cause of Tinnitus:
      Still unknown... possibly noise exposure?
      True. Lots of customers.
       
    5. Vinnitus
      Tired

      Vinnitus Member Benefactor

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      So, we are almost another year further down the line. What ever came from this drug?
       
    6. Aaron123

      Aaron123 Member

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      I believe Audion is developing it.
       
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    7. Vinnitus
      Tired

      Vinnitus Member Benefactor

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      Oh yes, you are right. Didn't Audion plan for clinical trials in 2017? That might mean they made some good progress with this compound or one of the "related" compounds mentioned in the quote below...

      http://cen.acs.org/articles/92/i14/Sound-Science.html
       
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    8. Jiri
      No Mood

      Jiri Member Benefactor

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      So it's 2018. That's 5 years from the firts post and other posts from 2013 on this LY411575 compound that's supposed to regenerate auditory hair cells.

      Any progress?? Is it available yet?
       
    9. dpdx
      Disappointed

      dpdx Member Benefactor Hall of Fame

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      You will have to wait quite some time.
       
    10. Paulmanlike

      Paulmanlike Member Benefactor Hall of Fame

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      No but if you're not up to date

      - phase 1 trail completed for frequencys compound. Successful meaning that the drug has potentially reached the cochlear without any serious adverse effects

      Phase 2 trial starting soon...

      Going to be a good few years yet that's even if it's successful.
       
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    11. Jiri
      No Mood

      Jiri Member Benefactor

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      Yes, I get it so potentialy another 10 years of waiting IF it is successful. Round and round.
       
    12. Mricha37

      Mricha37 Member

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      2008
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      Car subwoofers for 6 years

      FDA will fast track this if successful
       
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    13. Coleoptere
      Alone

      Coleoptere Member

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      Might be Audion. So see the other thread.
       
    14. Aaron123

      Aaron123 Member

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      No it's not available. Five years is quick to about right to get from that point to this point.

      This thread started to discuss a paper out of Albert Edge's lab. Since it came out of Edge's lab, my guess is that Audion was initially developing it, but they have since moved to LY3056480. Based on the paper from last February, Frequency is using LY411575.

      Given there are threads on Audion's trial and on Frequency, this thread doesn't seem very useful at this point.
       
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