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Sulodexide Possibly Benefits Chronic Tinnitus

@marcjrf, I got one box at the pharmacy in terminal 4 of Madrid Barajas airport. You can email them beforehand, in my experience they answer pretty quickly. I emailed them in Spanish.
 
I think I am start getting positive results so far.

But I'll wait at least for 30 days of taking Sulodexide and some time after discontinuation, to see if it is not placebo and results are sustainable.

Then I'll shed more details.

Hi kestokas,
could you please tell us how your experience is going. I live in Spain and considering talking about this with my social security doctor. Thank you.
 
Hi AmePerdue,
Thank you for informing, I will try it, my social security doctor thinks it may be a good option and has prescribed them for me. I will be updating the information.
 
Is your plan to take one in the morning and one in the evening for 40 days?
In the beginning, yes. However, I believe that after 30 days, I will increase the dosage to 4 pills, since I have read that it is a very safe drug used for preventive purposes, etc., with no risk of bleeding.

And I opted not to take it with Melatonin because (just in my opinion!) Melatonin works by soothing the nervous system and creating the perception of diminished tinnitus (temporarily).

Nonetheless, I have no expectations. My tinnitus has a very evident cause: I lost part of my hearing as a result of an SSHL episode, and some of my synapses simply perished.

I'm not sure how a medicine that enhances blood flow may help in such a situation.
 
Update:

I need to say that I am trying Suledoxide after very, very huge spike I got during my flu/pharyngitis episode.

After I started to take the pills, the spike dropped to the baseline. I doubt that it is because of Sulodexide, probably just a lucky coincidence. I will continue to take the Sulodexide, of course, and see what happens further.
 
Unfortunately, there was a small spike again yesterday, so in addition to the Sulodexide, I used the only supplement (from many I tested) that actually works for me: natural Saffron spice, extracted by 20 mg of vodka. I awoke in near silence (the silent days are the ones I forgot I am having the tinnitus). I believe this is a Saffron impact rather than a Sulodexide effect because there has been insufficient time for it to occur.

For the time being, I'll add Saffron for one week and then continue with Sulodexide only to see how things go.
 
Hi, I've never seen Saffron mentioned on the forum before. Can you provide more information? Amount, form, etc.? Thanks.
 
Unfortunately, there was a small spike again yesterday, so in addition to the Sulodexide, I used the only supplement (from many I tested) that actually works for me: natural Saffron spice, extracted by 20 mg of vodka. I awoke in near silence (the silent days are the ones I forgot I am having the tinnitus). I believe this is a Saffron impact rather than a Sulodexide effect because there has been insufficient time for it to occur.

For the time being, I'll add Saffron for one week and then continue with Sulodexide only to see how things go.
What brand of Saffron spice? What do you mean extracted by 20 mg of vodka?
 
Was the result long lasting?
No, Saffron is not long lasting, and actually it seems that your body quickly adjusts to its effects, so it's not a cure. But it may relax you.

Saffron seems to work like an actual anti-depressant drug. Something like that:

Saffron (Crocus sativus L.): As an Antidepressant
Hi, I've never seen Saffron mentioned on the forum before. Can you provide more information? Amount, form, etc.? Thanks.
Here is the topic and you may find some useful info

Saffron Cure for Tinnitus?
What brand of Saffron spice? What do you mean extracted by 20 mg of vodka?
I don't think it is important what brand, I used one from Spain. Just be sure it is a real one, not a fake.

I am mixing around 15-20 sticks with 20 g of vodka.

But it seems you can extract the active material maybe also with milk.
 
Hi AmePerdue,
Thank you for informing, I will try it, my social security doctor thinks it may be a good option and has prescribed them for me. I will be updating the information.

Update:

I have been taking Sulodexide (Dovida) 30 mg twice a day.

A week later I had to stop treatment because there was a significant worsening.

I rested for a week and gave it another chance with the same result, worsening.

I suspect it was not the active ingredient, Sulodexide, but the excipients, this is what the package insert says:

Warnings on excipients: This medicine can cause allergic reactions because it contains Orange Yellow S (E-110) and Cochineal Red A (E-124). May cause asthma, especially in patients allergic to aspirin. May cause allergic reactions (possibly delayed) because it contains sodium ethyl parahydroxybenzoate (E-215) and sodium propyl parahydroxybenzoate (E-217).​

Unfortunately, the other commercial brand available in Spain, Aterina, has the same presentation of soft capsules and the same excipients.

Consequently, the experience with Sulodexide has not been positive and if it is attributable to the excipients as I suspect, I cannot contribute anything regarding the effect of Sulodexide on tinnitus.
 
Update:

I have been taking Sulodexide (Dovida) 30 mg twice a day.

A week later I had to stop treatment because there was a significant worsening.

I rested for a week and gave it another chance with the same result, worsening.

I suspect it was not the active ingredient, Sulodexide, but the excipients, this is what the package insert says:

Warnings on excipients: This medicine can cause allergic reactions because it contains Orange Yellow S (E-110) and Cochineal Red A (E-124). May cause asthma, especially in patients allergic to aspirin. May cause allergic reactions (possibly delayed) because it contains sodium ethyl parahydroxybenzoate (E-215) and sodium propyl parahydroxybenzoate (E-217).​

Unfortunately, the other commercial brand available in Spain, Aterina, has the same presentation of soft capsules and the same excipients.

Consequently, the experience with Sulodexide has not been positive and if it is attributable to the excipients as I suspect, I cannot contribute anything regarding the effect of Sulodexide on tinnitus.
That's a huge shame, but it's great you found the probable cause for the worsening. One more data point for the rest of us...
 
UPDATE:

I've taken Sulodexide for almost two months.

The main side effect is an some aggravation of my pre-existing gastric reflux disorder. But bearable.

The main conclusion so far: it's helping my tinnitus somehow. It doesn't really treat or cure it, but it somehow reduces, not the base level itself, but the amount and intensity of spikes. They have been low throughout the whole period of taking it, maybe a couple of small, quickly subsiding spikes.

Before Sulodexide the amount and intensity of spikes were higher.

I want to continue taking it and see if I can get more benefit. Later I will try to stop and see if the perceived benefits persist.
 
UPDATE:

I've taken Sulodexide for almost two months.

The main side effect is an some aggravation of my pre-existing gastric reflux disorder. But bearable.

The main conclusion so far: it's helping my tinnitus somehow. It doesn't really treat or cure it, but it somehow reduces, not the base level itself, but the amount and intensity of spikes. They have been low throughout the whole period of taking it, maybe a couple of small, quickly subsiding spikes.

Before Sulodexide the amount and intensity of spikes were higher.

I want to continue taking it and see if I can get more benefit. Later I will try to stop and see if the perceived benefits persist.
Are you still taking it? How was your tinnitus caused?
 

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