Tinnitus Talk spoke with the Hough Ear Institute, a non-profit research organization that focusses on restoring hearing. They are working on two hearing regeneration treatments that could very well have benefits for tinnitus sufferers.
In this episode, we spoke with Dr. Richard Kopke and Justin DeMoss. They explain the mechanisms behind their treatments and how hearing restoration can be achieved. They take us through the different phases of research and development required to get new drugs to market, and some of the challenges faced along the way. Of course, we also touch on the topic of whether restoring hearing could cure tinnitus.
The episode includes an announcement about an exciting new partnership with pharmaceutical company Oblato to take Hough’s hearing loss pill through the next phases of clinical trial and assess its potential for tinnitus.
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Skip to: 00:00 Introduction to Hough and its work.
Our vision is that all who have ears will hear.
Skip to: 10:20 Personal experiences with tinnitus and how it can affect people.
Skip to: 13:26 Outline of Hough’s two treatments under development and current stage of research.
Skip to: 20:54 Will treatments benefit tinnitus and/or hyperacusis?
The pre-clinical data for tinnitus are pretty strong and reproducible […] We see a number of biomarkers associated with tinnitus that are normalized.
Skip to: 23:38 Why is animal testing necessary?
Skip to: 25:45 Funding and partnerships.
Skip to: 40:39 What can tinnitus patients do to help?
What people who suffer from tinnitus can do is to increase their knowledge of the scientific research that’s being done versus the popular fads that don’t have science behind them.
Skip to: 48:48 Rough timelines for bringing treatments to market.
Skip to: 51:20 In-depth explanation of hearing loss pill.
This combination product can actually robustly prevent the ongoing accumulation of the neurotoxic tau protein that can be a consequence of noise or blast exposure.
Skip to: 01:02:02 In-depth explanation of injection treatment.
Skip to: 01:09:25 Does restoring hearing cure tinnitus?