How many people have chronic, severe tinnitus? What types of tinnitus exist? And why do clinical trials for tinnitus keep failing? The answers to all those questions lie in biobank data.
Tinnitus, Ingrained in the Brain? — Prof. Dirk De Ridder
Prof. Dirk De Ridder is one of the most cited tinnitus researchers, a very eloquent speaker, and a passionate advocate for more and better tinnitus research. He seeks solutions to tinnitus in previously unexplored areas.
The Sound of Science — Otonomy
According to David Weber, CEO of Otonomy, there are signs of heightened interest among investors in hearing science. This is good news for all of us. We take a deep dive with Otonomy’s executives into their drug pipeline, covering hearing loss and tinnitus.
Objectifying Tinnitus — The Bionics Institute
Tinnitus has always seemed ungraspable; you hear something that others do not. How can we measure this objectively? The Bionics Institute believes they can. If they are right, this would be a breakthrough in supporting the development of better treatments for tinnitus.
Tinnitus and the Power of Prediction — Dr. Will Sedley
This episode will give you a deeper understanding of the different models that explain the brain mechanisms underlying tinnitus. Dr Will Sedley outlines his own theory, based on predictive processing. We also cover issues like how to develop an objective marker of tinnitus and the thorny topic of whether tinnitus subtypes really exist or not.
Hearing Lost and Found — Frequency Therapeutics
This is your chance to learn all about the hearing regeneration treatment FX-322 being developed by Frequency Therapeutics. We spoke with Carl LeBel about the promising results of their Phase 1 trial, the potential benefits for tinnitus, why speech intelligibility should be the primary measure of hearing, and when the drug might reach the market.
Reviving Retigabine for Tinnitus — Thanos Tzounopoulos, PhD
A drug to quieten your tinnitus, that’s what Thanos Tzounopoulos, PhD, is working on. The drug targets potassium ion channels in the brain. These channels – or so the theory goes – are compromised in tinnitus patients, thus triggering the neural hyperactivity perceived as tinnitus. In spite of trials and tribulations in getting the drug ready for clinical trials, Thanos is optimistic about his chances for success.
Healing Hearing, Silencing Tinnitus? — Hough Ear Institute
While curing tinnitus remains a conundrum, important advances are being made in the field of hearing regeneration, which might also benefit tinnitus sufferers. The Hough Ear Institute talks about two hearing restoration treatments under development.
Transforming Hyperacusis Research — Bryan Pollard
Sound discomfort and pain can be a hard burden to bear. We talked to Bryan Pollard about hyperacusis, a condition even more poorly understood than tinnitus. Luckily, recent scientific breakthroughs have opened up new treatment avenues.
Hearing In, Tinnitus Out — Prof. Marcelo Rivolta
Do you want to know what stem cells are and how they can treat hearing loss and tinnitus? Learn all about it in this podcast! Featuring professor Marcelo Rivolta, a specialist in hearing regeneration who recently started his own biotech company.