Azithromycin and Doxycycline and Increased Tinnitus

Discussion in 'Dr. Stephen Nagler (MD)' started by Willie Discus, May 7, 2015.

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    1. Willie Discus

      Willie Discus Member

      Tinnitus Since:
      I´ve had tinnitus for a little over a year, it all probably started because of an ear infection..I have a bacterial disease called Chlamydia pneumonie that I was diagnosed with in the autumn of 2013, but I´ve probably had it for many years and have had severe healthproblems because of it. I can hardly do anything anymore because o fatigue and muscleweakness.

      The only way to cure this disease is by taking a CAP(combination antibiotic protocol). So a month ago I started taking doxycycline 100 mg daily but unfortunately it worsened my tinnitus a I stopped taking it and the ringing went back to my normal level..I´ve been in contact with my doctor who says I can try azithromycin instead. Later in the treatment I will also add tinidazole for a couple of days every month. The treatment will go on for at least a year.

      I´ve read here that you don´t recommend that tinnitussufferers take azithromycin..
      Another alternative i Clarithromycin...what do you think about that?
      Or do you know of any other alternatives?

      I´m in a really bad situation because I need to treat my disease but I don´t want to worsen my tinnitus..Don´t know what to do...
    2. Dr. Nagler

      Dr. Nagler Member Clinician Benefactor

      Atlanta, Georgia USA
      Tinnitus Since:
      Hi Willie. Nice hat. A real fashion statement! With my hairline, I'm always looking for that sort of thing! :)

      OK. Here's the deal with clarithromycin. It belongs to the class of drugs known as macrolide antibiotics. Well, azithromycin is another macrolide antibiotic - so under normal circumstances I would say that since one macrolide can be a problem, you should stay away from all of 'em. But it turns out that statistic-wise azithromycin really isn't all that much of a problem in the first place. What happened with azithromycin was that way back in 2003 I saw like four patients in a row who had developed severe intrusive tinnitus while on azithromycin. So I said to myself, "Shit, gotta stay away from that one!" But since that time a dozen years ago, I don't think I've seen a single patient who developed tinnitus while on azithromycin. That's why I say my concerns about azithromycin are based on anecdote rather than data.

      Which is an incredibly roundabout way of saying that I really don't think clarithromycin should be a problem for you.

      Hope this helps.

      stephen nagler

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