British Tinnitus Association — Annual Tinnitus Research Review 2017

Discussion in 'Research News' started by Steve, Jul 14, 2017.

    1. Steve
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      Steve Member Benefactor Hall of Fame Advocate

      Location:
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      Cause of Tinnitus:
      Flu, Noise-induced, Jaw trauma
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    2. Rosemerry
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      Rosemerry Member Benefactor

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    3. ABakos
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      ABakos Member Benefactor

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    4. EatMoTacos
      No Mood

      EatMoTacos Member Benefactor

      Tinnitus Since:
      07/2009
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      Loud Music
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    5. AUTHOR
      AUTHOR
      Steve
      Creative

      Steve Member Benefactor Hall of Fame Advocate

      Location:
      Sheffield, UK
      Tinnitus Since:
      2003
      Cause of Tinnitus:
      Flu, Noise-induced, Jaw trauma
      This is a real emerging area of research, I did some searching this morning and there are a few things around. There is research into auditory hallucination in schizophrenia that may or may not be relevant (beyond my level of understanding to know if it is :))

      There is a fairly long read here although it's from 2012 - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3491818/ - The conclusion section says:

      miRNA involvement in the development and maturation of the inner ear and the auditory mechanism has been demonstrated numerous times. The most relevant to inner ear disease is the mutations in the seed region of miR-96, causing deafness in both humans and mice. This remarkable finding initiated a new paradigm in the deafness gene hunt. This was the first time that a single mutation in a miRNA was found to lead to deafness.

      The implication that a single mutation in a miRNA can lead to deafness is not trivial, since it is not a direct result of the mutation, but rather, a result of many small cumulative events, caused by both the loss of inhibition on the miR-96 targets, and gain of function of the targets now recognized by the new mutated seed region. This complex disease-causing mechanism had led us to believe that there is much more to miRNA involvement in disease than previously known.

      As new deep sequencing technologies are becoming more readily available, the miRNA field will rapidly grow and expand, identifying new miRNAs regulating important inner ear functions. Many diseases may be demonstrated to be affected by miRNA mutations, opening a vast potential for a future role for miRNAs as therapeutic agents.
       
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    6. Bobbie7
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      Bobbie7 Member Benefactor

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      @Steve - Thank you for your post about the enlightening BTA conference report on tinnitus and also for your work both on the forum and bringing news of research to us.

      I began reading the report and noticed the British Tinnitus Association "Plug Em" campaign which will serve to alert young people in England about the danger of noise trauma and the importance of self-protection. I think this is a wonderful idea and wish such a public service announcement would be implemented in the United States as, hopefully, it would serve to prevent countless people from suffering T here. As it stands now, apparently tinnitus doesn't rise to the level of concern/ interest/importance in the US as it does in England. A fascinating read thus far.

      Best wishes,
      Barbara
       
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    7. Markku
      Inspired

      Markku Founder Staff Podcast Patron Benefactor Hall of Fame Advocate

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      Fully agree Barbara - earlier this year we made this:

       
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    8. Bobbie7
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      Bobbie7 Member Benefactor

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      @Markku - Saw the video, it's excellent and TT is doing a great service. The site is very interesting and informative --- I hope all young people will take to heart the important message. You and your team are doing fine work; congratulations on the new TT "offspring". :)
       
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    9. canyonero

      canyonero Member

      Location:
      Eastern US
      Tinnitus Since:
      7/2014
      Cause of Tinnitus:
      Acoustic Trauma?
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    10. jer

      jer Member

      Tinnitus Since:
      06/2015
      Cause of Tinnitus:
      Acoustic trauma
      That might be so, especially since there are a lot of different issues that can cause tinnitus. But in that report ther are also a lot of interesting studies, trials etc. I personally think they are making good progress towards a treatment / cure. And also remember guys, it can also come very fast and from an unexpected source. Take for example trobalt. Many people found some relief or complete relief from this medicine. And that came just by people trying things out themselves. Also take for example penicillin. The guy who discovered that wasn't even looking for antibiotics.
       
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    11. AUTHOR
      AUTHOR
      Steve
      Creative

      Steve Member Benefactor Hall of Fame Advocate

      Location:
      Sheffield, UK
      Tinnitus Since:
      2003
      Cause of Tinnitus:
      Flu, Noise-induced, Jaw trauma
      Thank you Barbara :)

      There are conflicts still but research is progressing a lot faster than it was even a short time ago. The more research there is the better it is for us.
       
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    12. Codaz

      Codaz Member

      @Steve Thanks for the report but nowhere is somatic T (TMJ) mentioned.
       
    13. AUTHOR
      AUTHOR
      Steve
      Creative

      Steve Member Benefactor Hall of Fame Advocate

      Location:
      Sheffield, UK
      Tinnitus Since:
      2003
      Cause of Tinnitus:
      Flu, Noise-induced, Jaw trauma
      I don 't remember where I saw it but one of the themes of the TRI conference next year is somatic tinnitus.
       
    14. glynis
      Feminine

      glynis Member Benefactor Ambassador Hall of Fame

      Location:
      England, Stoke-on-Trent
      Tinnitus Since:
      2004
      Cause of Tinnitus:
      Meniere's Disease
      Hi @Steve,
      I have a book version of the Annual Research Review 2017 that Nic Wray sent out to me.

      Will have a good read of it and highlight in pencil parts I can read out to our tinnitus support group next week.
      Love glynis
       
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    15. AUTHOR
      AUTHOR
      Steve
      Creative

      Steve Member Benefactor Hall of Fame Advocate

      Location:
      Sheffield, UK
      Tinnitus Since:
      2003
      Cause of Tinnitus:
      Flu, Noise-induced, Jaw trauma
      Same with me :) I need to have a good read, I've only skimmed it so far. I think it's so important to have a review of the research, glad that the BTA are doing this every year.
       
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