Hough Ear Institute's Hair Cell Regeneration Project

Discussion in 'Research News' started by all to gain, Oct 2, 2019.

    1. Rb86

      Rb86 Member

      Tinnitus Since:
      5/31/19
      Cause of Tinnitus:
      Noise
      I find it highly odd that we have multiple companies suddenly chasing the same therapy with very similar methods.

      I actually believe something is happening behind the scenes in the science community to spark this.

      There's no way 3 or more companies discovered the same thing at the same time.

      Some new diagnostic, or small molecule development happened for the community and pushed everyone onto the same path.

      This is just my hunch of course. But yeah, it's very odd, in a good way.
       
    2. JohnAdams
      Festive

      JohnAdams Member Benefactor Hall of Fame

      Location:
      Vatican
      Tinnitus Since:
      May 1st 2018
      Cause of Tinnitus:
      Aspirin Toxicity/Possibly Noise
      Why do we need a medicine for tinnitus if we have all the CBT that we could dream of?
       
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    3. Jurger

      Jurger Member

      Tinnitus Since:
      2004
      Cause of Tinnitus:
      Hearing loss
      Most likely because our biological understanding of the inner ear has grown tremendously the last decade.
       
      • Agree Agree x 3
    4. ChrisBoyMonkey

      ChrisBoyMonkey Member Podcast Patron

      Location:
      CA
      Tinnitus Since:
      04/2019
      Cause of Tinnitus:
      U.S. Army/Field Artillery Veteran
      They haven't said anything at all. That's just my estimate as they appear to be moving very fast on their own.

      You could always go for a trial if they have one near you to maybe get it sooner.
       
    5. AUTHOR
      AUTHOR
      all to gain

      all to gain Member

      Tinnitus Since:
      June 2019
      Cause of Tinnitus:
      dirty drugs
      I'm simply not optimistic at all. Why would I be? These drugs are not on the market now, and they may never make it that far. Only when they are on the market will I show some optimism. Even then it is a big unknown if they will help anyone.
       
    6. AUTHOR
      AUTHOR
      all to gain

      all to gain Member

      Tinnitus Since:
      June 2019
      Cause of Tinnitus:
      dirty drugs
      If I could go back in time I would have taken CBT over going on Prozac, which has led to me getting tinnitus.

      But I know what you mean!!
       
    7. Jim51042

      Jim51042 Member

      Tinnitus Since:
      3/28/16
      Cause of Tinnitus:
      Headphone use
      We don't necessarily need imagining technology although that would be very helpful. All the study would need to do is apply the compound to one ear only, wait for said individual to die, and then dissect that person. If there is a big difference between the nerve connections from the treated ear versus the non-treated ear you can infer the injection had an impact.

      Who wants to volunteer??:ROFL:;)
       
      • Agree Agree x 1
    8. AUTHOR
      AUTHOR
      all to gain

      all to gain Member

      Tinnitus Since:
      June 2019
      Cause of Tinnitus:
      dirty drugs
      If they offer my wife and children enough money to last them a life time I may be that volunteer.
       
    9. JohnAdams
      Festive

      JohnAdams Member Benefactor Hall of Fame

      Location:
      Vatican
      Tinnitus Since:
      May 1st 2018
      Cause of Tinnitus:
      Aspirin Toxicity/Possibly Noise
      That's what CBT is really for, depression, anxiety, phobias etc. Not distress from actual physical diseases.
       
      • Agree Agree x 7
    10. AUTHOR
      AUTHOR
      all to gain

      all to gain Member

      Tinnitus Since:
      June 2019
      Cause of Tinnitus:
      dirty drugs
      Yep. People don't see tinnitus as something real. Hell, my wife thinks it is a figment of my imagination. She says lift the depression and it will disappear. Err no!! Lift the depression and I'll still be left with tinnitus, but the depression isn't going anyway because of the tinnitus. If that all made sense.
       
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    11. ChrisBoyMonkey

      ChrisBoyMonkey Member Podcast Patron

      Location:
      CA
      Tinnitus Since:
      04/2019
      Cause of Tinnitus:
      U.S. Army/Field Artillery Veteran
      It does, it's a vicious cycle. You can try to get used to the sound (you don't have to take CBT to try). I've been trying to do that with my nearly unmaskable ringing and I'm slowly getting there. I sure as hell still hate it though.

      I'm lucky that my wife has been very supportive. She sure knows that what I have is real. I was the polar opposite of the way I am now before I had this.
       
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    12. Rb86

      Rb86 Member

      Tinnitus Since:
      5/31/19
      Cause of Tinnitus:
      Noise
      Well it's a good thing you're on this forum regarding a drug that's in the works, shitting on it for the rest of us hopefuls.
       
      • Like Like x 1
    13. AUTHOR
      AUTHOR
      all to gain

      all to gain Member

      Tinnitus Since:
      June 2019
      Cause of Tinnitus:
      dirty drugs
      Same here. I was the polar opposite more often than not.

      Did you have nay hearing loss and what are you doing to try and get used to it?
       
    14. AUTHOR
      AUTHOR
      all to gain

      all to gain Member

      Tinnitus Since:
      June 2019
      Cause of Tinnitus:
      dirty drugs
      Also, even if these drugs do hit the market, I reckon they will not suddenly become widely available due to cost and other reasons. And as first generation drugs they will probably be riddled with side effects.

      I'm just being realistic! Or at least i think I am.
       
      • Hug Hug x 2
    15. ChrisBoyMonkey

      ChrisBoyMonkey Member Podcast Patron

      Location:
      CA
      Tinnitus Since:
      04/2019
      Cause of Tinnitus:
      U.S. Army/Field Artillery Veteran
      @Justin De Moss Any update on that potentially awesome news you might have?
       
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    16. Piney

      Piney Member

      Tinnitus Since:
      March 2018
      Cause of Tinnitus:
      Shingles virus
      When is this podcast I can’t find the date in the threads? This is bold coming outright and saying we have a pill which will end the T. I’m just going to say it, this whole system is screwed up to me, I can buy a bottle of lies at CVS with no regulation but if a true cure is out there wait for the patients and companies to reach in their pocket for a 3 to 10 year release. It’s crap, put the bottle on the shelf in your clinic and I’ll buy it just like the rest of the jars you see in the isle at a GNC.
       
      • Agree Agree x 2
    17. JohnAdams
      Festive

      JohnAdams Member Benefactor Hall of Fame

      Location:
      Vatican
      Tinnitus Since:
      May 1st 2018
      Cause of Tinnitus:
      Aspirin Toxicity/Possibly Noise
      Nah.
       
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    18. AUTHOR
      AUTHOR
      all to gain

      all to gain Member

      Tinnitus Since:
      June 2019
      Cause of Tinnitus:
      dirty drugs
      Why not? It would be great if they aren't. I've had my life screwed up enough by side effects already.
       
    19. JohnAdams
      Festive

      JohnAdams Member Benefactor Hall of Fame

      Location:
      Vatican
      Tinnitus Since:
      May 1st 2018
      Cause of Tinnitus:
      Aspirin Toxicity/Possibly Noise
      Well for one, this pill has already been shown to be safe, and the other stuff being tested for tinnitus/hearing loss haven't shown any adverse effects that I'm aware of.

      OTO-413 hasn't reported any results yet but I have ***inside baseball*** that it will also be safe.
       
    20. Piney

      Piney Member

      Tinnitus Since:
      March 2018
      Cause of Tinnitus:
      Shingles virus
      Everything has a side effect, these companies take in millions of dollars and have produced zilch in tinnitus. They need to find away around the red tape. If they have a magic pill and it works I would make a healthy donation for it towards trials. How much money is wasted on trials that produce nothing? How much should the patients donate without results?
       
    21. Piney

      Piney Member

      Tinnitus Since:
      March 2018
      Cause of Tinnitus:
      Shingles virus
      Exactly, and if people are worried then they don’t have to buy it. All of the drugs doctors give you mess up enzymes, BP levels etc. If it passed the safety trials release it, but don’t take 4 years and all the funds to say sorry it didn’t work. It may not work in three days when you take it or for years when these trials get through.
       
      • Agree Agree x 1
    22. Piney

      Piney Member

      Tinnitus Since:
      March 2018
      Cause of Tinnitus:
      Shingles virus
      Some people here pay money to the ATA, instead of me just getting angry, I called them and asked them to check up on this institution since it’s not on their website. They said they will and get back to me. I’m over it, fantasy or realty people need real answers.
       
    23. AUTHOR
      AUTHOR
      all to gain

      all to gain Member

      Tinnitus Since:
      June 2019
      Cause of Tinnitus:
      dirty drugs
      When is a drug considered safe? I mean, most drugs have lists of side effects attached to them and are considered safe. I wonder what the criteria is?
       
    24. Defiant-Decay

      Defiant-Decay Member

      Tinnitus Since:
      2019
      Cause of Tinnitus:
      Loud noise/ music in headphones
      Does Hough Ear Institute have enough funding to go forward with research?
       
    25. JohnAdams
      Festive

      JohnAdams Member Benefactor Hall of Fame

      Location:
      Vatican
      Tinnitus Since:
      May 1st 2018
      Cause of Tinnitus:
      Aspirin Toxicity/Possibly Noise
      No side effects.
       
    26. FGG

      FGG Member Podcast Patron Benefactor

      Tinnitus Since:
      01/2019
      Cause of Tinnitus:
      Multi-factorial
      I think for phase 1, that means no serious side effects, not no side effects.
       
      • Agree Agree x 1
    27. Defiant-Decay

      Defiant-Decay Member

      Tinnitus Since:
      2019
      Cause of Tinnitus:
      Loud noise/ music in headphones
      But all drugs have side effects, drugs for Rheumatoid Arthritis can actually cause cancer.
       
    28. JohnAdams
      Festive

      JohnAdams Member Benefactor Hall of Fame

      Location:
      Vatican
      Tinnitus Since:
      May 1st 2018
      Cause of Tinnitus:
      Aspirin Toxicity/Possibly Noise
      There is no phase 1 data.
       
    29. FGG

      FGG Member Podcast Patron Benefactor

      Tinnitus Since:
      01/2019
      Cause of Tinnitus:
      Multi-factorial
      I just meant in general to be considered safe and proceed to phase 2. A drug can be considered "safe" if it had minor side effects.
       
      • Agree Agree x 1
    30. JohnAdams
      Festive

      JohnAdams Member Benefactor Hall of Fame

      Location:
      Vatican
      Tinnitus Since:
      May 1st 2018
      Cause of Tinnitus:
      Aspirin Toxicity/Possibly Noise
      BDNF isn't a drug. It is a biological compound that is already present in your body.

      Also, the Hough Ear pill isn't something that you have to stay on. It is a temporary intervention. It is going to be fine. Stop worrying.
       
      • Agree Agree x 2

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