Neuroinflammation Mediates Noise-Induced Synaptic Imbalance and Tinnitus in Rodent Models

Discussion in 'Research News' started by Krolo, Jun 18, 2019.

    1. foam

      foam Member

      Tinnitus Since:
      7/2019
      Cause of Tinnitus:
      Unknown
      I'll send you a message about it
       
    2. Bill Bauer
      No Mood

      Bill Bauer Member Hall of Fame

      Tinnitus Since:
      February, 2017
      Cause of Tinnitus:
      Acoustic Trauma
      Take Proscar - problem solved.
       
      • Like Like x 1
    3. Mal58

      Mal58 Member

      Tinnitus Since:
      2013
      Cause of Tinnitus:
      Loud noise? Headphones?
      How do they know the mice have tinnitus?
       
      • Good Question Good Question x 1
    4. Notch

      Notch Member

      Tinnitus Since:
      25/3/2019
      Cause of Tinnitus:
      Dentist clean
      Silent gap test.
       
      • Agree Agree x 1
      • Informative Informative x 1
    5. JohnAdams
      Festive

      JohnAdams Member Benefactor Hall of Fame

      Location:
      Sector Alpha
      Tinnitus Since:
      May 1st 2018
      Cause of Tinnitus:
      Aspirin Toxicity/Possibly Noise
      Well it stopped thinning but I'm cautiously keeping an eye on it.
       
    6. Mal58

      Mal58 Member

      Tinnitus Since:
      2013
      Cause of Tinnitus:
      Loud noise? Headphones?
      OK, I googled it:

      "testing if the mice can detect a short gap in a constant, low-level background noise that happens just before a loud noise. If the mouse can hear it, then over time, it learns that the gap means there’s about to be a loud noise, so they don’t jump as much when it happens. But if the mouse has tinnitus, that is, if it’s constantly hearing a ringing in its ears, then it won’t hear the gap warning it about the noise, so they jump just as much the tenth time it happens as they did the first time. "
       
      • Informative Informative x 1
    7. dayma
      Frustrated

      dayma Member Benefactor

      Tinnitus Since:
      1/6/2018
      Cause of Tinnitus:
      UNKNOWN
      I am a lifter and use both. Never really helped with inflammation. I do massages and kryo for that.
       
    8. Bill Bauer
      No Mood

      Bill Bauer Member Hall of Fame

      Tinnitus Since:
      February, 2017
      Cause of Tinnitus:
      Acoustic Trauma
      I don't believe that the thinning can just stop by itself. The thinning process can be very slow, but keep in mind that Proscar doesn't really cause one to regain the lost hair. Proscar allows you to slow down the thinning. Ideally, for about 10 years or so, you will get to mostly keep the amount of hair you have had when you began taking Proscar. So if this is important to you, and you are ok with the possible side effects of Proscar, it is better to begin taking it as soon as possible.
       
    9. JohnAdams
      Festive

      JohnAdams Member Benefactor Hall of Fame

      Location:
      Sector Alpha
      Tinnitus Since:
      May 1st 2018
      Cause of Tinnitus:
      Aspirin Toxicity/Possibly Noise
      Yeah, I know, my ol' pal has been on it since he was 20. I don't think my hair thinning was natural. I think it was from eating like 12 curcumin capsules every day.
       
      • Like Like x 1
    10. ChrisBoyMonkey

      ChrisBoyMonkey Member Podcast Patron

      Location:
      CA
      Tinnitus Since:
      04/2019
      Cause of Tinnitus:
      U.S. Army/Field Artillery Veteran
      Here's a link from a local radio station where it seems they got an interview with the University of Arizona's lead researcher on the tinnitus neuroinflammation research Dr. Shaowen Bao. They added a few seconds of it on the link.

      https://kjzz.org/content/1132831/ua-rodent-study-identifies-possible-tinnitus-treatment-target

      The station said that Dr. Bao cautioned it is new research, and if human trials will happen, it would be "years in the future".

      Let's hope by years they mean only like 2.
       
      • Informative Informative x 5
      • Like Like x 2
      • Agree Agree x 1
    11. just1morething
      Benevolent

      just1morething Member Benefactor

      Location:
      U.S.
      Tinnitus Since:
      2008
      Cause of Tinnitus:
      barotrauma, noise exposure, TMJ, neck?
      Becoming a "chrome dome" has to be better than having noise in your nut.
       
      • Agree Agree x 2

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