New University of Michigan Tinnitus Discovery — Signal Timing

I have multiple frequencies of T. I have a 13kHz hiss and a 1.56kHz ring in the right ear. Both of these are modulated by different parts of my face. The 13kHz is louder when I clench my jaw or tilt my head to the left. The 1.56kHz is increased by stretching my back muscles like when I yawn or plugging my ear and changing the air pressure. So I would assume these would need to be targeted differently. I also have 1.26khz in the left ear, but it is much quieter and can be modulated the same way as the 1.56khz. Does that help?

 

Anyone knows how many participants will be in this upcoming trial? Will it be a phase 3 with thousands of people?

 

No this is the last phase.

 

Isn't Phase 3, the last phase?
@threefirefour

 

For drugs yeah. Not devices. We get lucky there.

 

So this is FDA Phase 2, which is the final FDA Phase for devices?

 

Pivotal. The current trial is pivotal.

 

I'm putting way too much hope in this device. If this doesn't work that's going to crush me.

 

Agreed. When people started talking about a predicted release date in 6 years that was bad enough...

 

Honestly, I'm much more hopeful for Frequency Therapeutics above all of this. If this doesn't work out at least we've got 2 or 3 other options for bimodal stimulation.

 

I think Dr. Shore has a few tricks under her sleeve. She has been working / studying on it for 2 decades. I think she is the number one person to understand tinnitus so far.

I am sure there are things the public does not know about her strong belief why it will work.

I think she is getting closer to solve the issue of tinnitus or at least start to treat it.

 

I'm exactly like you: a high frequency permanent hiss + medium freq ringing at around 1.2khz which is my most difficult one to habituate when sleeping. The ringing is a lot more "crazy" than hisses to me, even if lower in volume.

And I also have a pure tone at low freq, more like a factory you hear in the night from your house and only low freq are reaching you.

Nevertheless, I think all of them can be cured the same way. If you hear the med freq ring when you yawn it is simply because it is more quiet than your hiss and when you yawn you close your ear so the environment sound level gets a lot more quiet. I don't hear it during the day while working, in the car etc. because the env. sound level is around 55 to 65db when you think it's being quiet. But when you're home it's around 35-40db if you live in a quiet place. So there's more place for your ring to be heard. When you yawn, in every case your env. level gets even lower than 35db.

I have many times wondered if it had something to do with pressure on the ear (yawning or pushing the air with the finger in the channel) but I prefer to think this is all related to a suffering cochlea which could be cured with FX-322 or similar.

 

Someone who's in the trial, told me that they are waiting on the devices, that's why it hasn't started.

 

I have a question for anyone who has read more than I have about this stuff. I’m sorry if this has already been covered in this forum.

What are the differences/similarities between the University of Michigan device and the Neuromod device.

It seems to me that the Neuromod device is closer to market than the University of Michigan device.

I’ve read that the Neuromod device could enter European market within the year.

Medtech Strategist from September 14, 2018 has a decent article.

 

The UM study is a Crossover-design:
https://weekly.biotechprimer.com/from-drug-development-to-approval-part-two/

 

There is never gonna be a cure for tinnitus. We are all going to die and the last thing we hear is going to be our tinnitus

 

Are you a God?

 

He'd better not be

 

@dan have some hope man , they trying hard to find something. I know it not easy living with T . It pure hell.

 

No. But trust me if you aren't going to live to 1000 years old - you won't see a cure in your lifetime.

They didn't even cure Cancer yet and look how much funding Cancer gets, how many researchers are working on this worldwide.

And look how many researchers are working on a cure for tinnitus? ONE (1) - that's right, one person - that Greek professor Thanos Tzounopoulos or whatever.

 

Dude sorry but please can you just shut up!

 

Amazing DBS Before & After | 225-769-2200...

When I saw this video for the first time I was convinced that a cure for tinnitus is not far.

 

Wow this is amazing, can't believe he got the relief so fast...

I wish this Susan Shore device works like this for our somatic tinnitus as well

 

Ugh...the fact that this is so possible is what makes it twice as hard to swallow

 

Maybe not a cure, but at least treatments. Why would three(3) different places be working on bi-modals if they didn't think it was at least slightly effective?

 

Is this only for somatic T? Mine does not change with body movements, even if I perform a somersault.

 

What if you do a somersault whilst - and at the same time - you stick out your jaw as far as you can?

 

Haha. It does not change.

 

I say try that in a pool filled with FX-322.

 

In the 1970's, it took a warehouse full of equipment to run a computer at 1/100th the speed of even a cheap smart phone in your pocket right now.

It has not even been 100 years since the discovery of antibiotics

200 years ago they were still using blood-letting as a treatment for just about anything

150 years ago, they used to think epilepsy was the possession of a demon

Less than 20 years ago, dial-up modems were the common way to access the internet at painfully slow speeds

Moore's Law has accelerated the digitization of our world beyond what even Bill Gates and Steve Jobs could have dreamed of

You cannot predict the future of medical technology. Research into Parkinson's, strokes, and other brain disorders has advanced a great deal in the last 15 years. Even if there is not a directed research effort to cure tinnitus, it is more than likely that other advances for a variety of brain disorders will unlock the key to treating and curing this disease.

On a side note, perhaps you should have a little faith in your fellow man, and even help initiate the process of advancing research. People use to feel helpless about heart disease and diabetes even in my lifetime, and now look how far we have come? It's fantastic.