Prof. Thanos Tzounopoulos Receives $2 Million Grant

Discussion in 'Research News' started by Jack Straw, Dec 4, 2018.

    1. Greg Sacramento

      Greg Sacramento Member Benefactor Hall of Fame

      Tinnitus Since:
      April 2011
      Cause of Tinnitus:
      syringing and now somatic T dental work
      In simple words without posting more supporting articles/links, the technical world needs to find better radiological methods to study small nerve fibers both motor and sensory within cranial networks that lead to other small nerve fibers networks that also lead to the ears and brain.

      There has been good mapping studies from brilliant researchers on lack of blood flow of major arteries for a second causing tinnitus, TMD and most other causes of tinnitus.
       
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    2. Don Tinny

      Don Tinny Member

      Location:
      Argentina
      Tinnitus Since:
      2017 (worsening)
      Cause of Tinnitus:
      Loud concert with ear plugs
      I hope Lenire works. It will be a better option. Drugs can have serious and permanent side effects after long term use.
       
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    3. erik
      Cool

      erik Member Benefactor

      Location:
      Washington State, USA
      Tinnitus Since:
      04/15/2012 or earlier?
      Cause of Tinnitus:
      Most likely hearing loss
      True and it was only a few years ago that the leading tinnitus researchers even agreed that tinnitus was a brain condition.
       
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    4. Alue
      No Mood

      Alue Member

      Tinnitus Since:
      01/2016
      Cause of Tinnitus:
      Acoustic Trauma
      Trobalt really helped me when I took it. I was lucky to not have any permanent side effects (that I know of). If there was a potassium channel opener with fewer side effects I'd take it.
      To get through all phases of FDA trials and be approved for prescriptions, most drugs take a minimum of 10 years. So you aren't too far off.
       
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    5. TuxedoCat
      No Mood

      TuxedoCat Member Benefactor Ambassador Advocate

      Location:
      US
      Tinnitus Since:
      April 2017
      Cause of Tinnitus:
      high frequency hearing loss
      The Eye and Ear Foundation of Pittsburgh
      University of Pittsburgh Hearing Research Center

      I recently received the newsletter, Sight and Sound, from the Eye & Ear Foundation of Pittsburgh. It reports on recent adoption of a team approach to forming ideas and engaging community members with the intent of educating the public about vision loss, hearing loss and other conditions, such as tinnitus.

      Two teams have been assembled already, one of which is a multidisciplinary team or taskforce in the Pittsburgh Hearing Research Center (PHRC) founded by Professor Thanos Tzounopoulos. The other is the Cornea Taskforce.

      "The PHRC team plans to develop a new method of classifying people and their hearing loss and tinnitus in a much more mechanistic and neuroscience-based way than has ever been used." The PHRC is in a unique position to accomplish this because it has a high level of expertise and access to patients through the auditory clinic that is completely connected with the PHRC by joint leadership.

      "The overarching goal of the PHRC and its taskforce is to help patients better manage their hearing loss and tinnitus, and to eventually find permanent solutions, not just treatments, to these devastating conditions."

      Future issues of Sight and Sound will report on the progress of the PHRC taskforce and others currently being formed in both Ophthamology and Otolaryngology.

      For more detailed coverage, please see pages 4 and 5 of the attached copy of the newsletter.

      TC
       

      Attached Files:

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    6. Ken219
      Frustrated

      Ken219 Member

      Location:
      New York Area
      Tinnitus Since:
      Summer of 1990
      Cause of Tinnitus:
      Noise exposure?
      USA is a suicidal society.

      'Lawn darts had been banned from being sold in the United States for many years. The ban was challenged in court in the late 1970s, prompting the Consumer Product Safety Commission to make a compromise ruling allowing their sale provided they were not marketed as toys.'

      The iPod sound level can go as high as 110 dB. It is recommended you do not listen at 110 dB.
       
    7. Watasha
      No Mood

      Watasha Member Benefactor

      Tinnitus Since:
      03/2018
      Cause of Tinnitus:
      Unknown
      Thanks for sharing!
       
    8. Ken219
      Frustrated

      Ken219 Member

      Location:
      New York Area
      Tinnitus Since:
      Summer of 1990
      Cause of Tinnitus:
      Noise exposure?
      It may be selfish of me but I'd prefer to keep the tinnitus thing a secret.
       
    9. TuxedoCat
      No Mood

      TuxedoCat Member Benefactor Ambassador Advocate

      Location:
      US
      Tinnitus Since:
      April 2017
      Cause of Tinnitus:
      high frequency hearing loss
      I especially love sharing news about researchers who recognize the value of interacting with patients. Such a refreshing alternative to "learn to live with it"! There really are people out there that care.
       
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    10. ChrisBoyMonkey

      ChrisBoyMonkey Member Podcast Patron

      Location:
      CA
      Tinnitus Since:
      04/2019
      Cause of Tinnitus:
      U.S. Army/Field Artillery Veteran
      Dr. Tzounopoulos seems to be one of the few that are vigorously on the case of tinnitus. I saw in a different thread someone had emailed him and his responses demonstrated that he is very intent on finding a real treatment for tinnitus.
       
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    11. TuxedoCat
      No Mood

      TuxedoCat Member Benefactor Ambassador Advocate

      Location:
      US
      Tinnitus Since:
      April 2017
      Cause of Tinnitus:
      high frequency hearing loss
      I received this today from the Foundation that supports research at University of Pittsburg. Note the timeline - Prof Thanos Tzounopoulos expects to submit an IND to FDA to begin clinical trials by 2021. Of course a lot could happen between now and then, however its good to see someone making real progress. -TC

      5150835f-808c-46ba-bee3-4f9cf6177836.png

      Developing a Cure for Tinnitus

      The Eye & Ear Foundation collects support from donors like you to help propel research forward. Whether big or small, our donors' gifts make a difference in the lives of patients and their families. One of our favorite stories that exemplifies the impact of continuous support in a given area of research is the story of how the Eye & Ear Foundation provided seed funding to Thanos Tzounopoulos, PhD and the team at the University of Pittsburgh which includes Peter Wipf, PhD, Distinguished Professor in the Department of Chemistry. This funding helped to secure larger grants from the National Institutes of Health and Department of Defense to advance research towards developing a molecule that could potentially be a cure for tinnitus.

      Learn how your support has made a difference in the graphic below (click to enlarge):

      c4f1687b-948a-4e86-b6b4-5c6ebf73d24c.jpg
      Your donations make a difference! As Dr. Tzounopoulos’s work progresses to the pre-clinical stage of development, we believe that now, more than ever, that the small gifts that we collect over time have the power to be transformational in pushing research findings into the hands of patients.

      To support this groundbreaking work, donate to The Eye & Ear Foundation.

      640c2169-4678-4716-9ae3-ae7781eebd83.png
      The Eye & Ear Foundation is a non-profit 501(c)(3) organization created solely to support the educational and research efforts of the Departments of Ophthalmology and Otolaryngology at the University of Pittsburgh. The Eye & Ear Foundation is the only foundation in the region which supports research and academic efforts to eradicate both hearing and vision loss.

      THE EYE & EAR FOUNDATION OF PITTSBURGH
       
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    12. ChrisBoyMonkey

      ChrisBoyMonkey Member Podcast Patron

      Location:
      CA
      Tinnitus Since:
      04/2019
      Cause of Tinnitus:
      U.S. Army/Field Artillery Veteran
      Awesome! We are finally starting to see his hopeful research start to materialize. Hopefully we see more of this from different avenues too.
       
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    13. TuxedoCat
      No Mood

      TuxedoCat Member Benefactor Ambassador Advocate

      Location:
      US
      Tinnitus Since:
      April 2017
      Cause of Tinnitus:
      high frequency hearing loss
      Indeed, CBM. News like this lifts my spirits. Now, the drug can fail any where along the way but this looks more like a real time line, a real road map. Finally, somebody that knows what they're doing.

      I've got to find my notes from the veterans project we started and get back on track with it. My mother passed and my son, his wife and my grandson were with us for a week so the project stuff's been put away while I was sidetracked.

      Take care, TC
       
    14. Bndsmheowqhe

      Bndsmheowqhe Member

      Tinnitus Since:
      2016
      Cause of Tinnitus:
      Loud noise exposure
      There are car stereos that go up to 170 dB. My tinnitus started after being trapped in a vehicle with a lunatic that decided to demonstrate how painfully loud his system was.
       
    15. ChrisBoyMonkey

      ChrisBoyMonkey Member Podcast Patron

      Location:
      CA
      Tinnitus Since:
      04/2019
      Cause of Tinnitus:
      U.S. Army/Field Artillery Veteran
      I'm sorry to hear that, and my condolences. Family is always first.

      It's great to at least see the invisible hand is at least moving on it's own. I've been adjusting to what seems to be a permanent spike/new baseline and am starting to somewhat rehabituate. I also recently left my job to change to a job where I won't have to hear my tinnitus all day long so I will begin to work on the things needed on my end too since now I have more freedom time.

      Your friend, CBM
       
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    16. Piney

      Piney Member

      Tinnitus Since:
      March 2018
      Cause of Tinnitus:
      Shingles virus
      Wow! Scientists and Clinicians coming together working as a chain to use all information towards the progression of a cure. I hope all the Device companies and Universities are listening. Maybe coming together and sharing info is for the greater good.
       
    17. Rb86

      Rb86 Member

      Tinnitus Since:
      5/31/19
      Cause of Tinnitus:
      Noise
      From an email with Professor Thanos:

      "In response to your question, yes we are getting closer. Many good labs and good people (clinicians, companies, etc) are working on this problem. We will conquer tinnitus."

      Nothing too new to report. But he's responsive and nice, and determined.
       
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