Been Lurking. My VERY High-Pitched Tinnitus Noise Bothers Me Most — Potential Cures on the Horizon?

Hello all,

I have tinnitus (lol why I'm here). I had brief periods of tinnitus since I was a child but I think being a musician finally did me in. I was around some really loud amps and PA's before but something about a particular experience seems to have done me in, it's been over a year.

My tinnitus is multiple tones that seem to come and go day by day but the one that really bothers me is a very very VERY high pitch noise. It is not there everyday but the days that it is there are HORRIBLE.

I've read some stuff here and elsewhere talking about potential cures* on the horizon but I need someone with a bit more knowledge to set me straight on what's coming, if anything.

Looks like I'm part of the gang now.

 

Hey, welcome to the forum.

So your tinnitus is evidently from noise exposure/damage to the inner ear (cochlea). Your brain is basically filling in missing auditory stimuli with it's own noise (maladaptive plasticity).

We are currently awaiting regenerative medicine to repair the damaged structures within the cochlea. Restoring these auditory pathways should restore hearing and thereby reverse ("cure") some or all of the tinnitus.

The two main cochlear structures susceptible to noise damage are (1) the outer and inner hair cells, and (2) the synapses that connect them to the auditory nerve. We've got drugs in clinical trials targeting both. Many of us will probably need at least one drug for both.

Hair cell regrowth:
FX-322
Audion's REGAIN
Hough's Injection

Synapse repair:
OTO-413
PIPE-515
Hough's Pill

~5 years seems to be a reasonable expectation for when we will start to see some of these drugs come to market. Some of the others on the forum are working on a layman's guide to regenerative medicine, but until then we have threads for each of these drugs in the research news section you can check out.

Hope this helps.

 

I'd just add to Tweedleman's synopsis that realistically maybe as soon as next year the long awaited Susan Shore device will come to market. This is a bimodal nueromodulation treatment. Right now there is Lenire with a first generation of this tech which while it has several converts seems mostly to be underwhelming. The general consensus is that Susan Shore's device (University of Michigan) is build on much more robust research and there is a lot of reasonable hope that it will allow a significant amount of relief to those with somatic tinnitus. There is an extensive thread on the topic.

 

Thanks for the info Tweedleman. 5 years huh?

 

Yep. This is why I've been an advocate for cryosleep.

 

Would you say that as time goes on there are more and more days when it isn't there?

Check out
https://www.tinnitustalk.com/thread...eone-else-who-has-tinnitus.26850/#post-307822

 

I've read some stuff here and elsewhere talking about potential cures* on the horizon but I need someone with a bit more knowledge to set me straight on what's coming, if anything.
https://www.frequencytx.com
Hopefully this biotech will provide us with a cure eventually.

 

Not really. It's random. Here today, gone tomorrow. I feel like sleep has something to do with it but other times I do not know what to think.

 

Will the Hough Pill or FX-322 help with all tinnits? What about Susan Shore's device? Is it solely for somatic tinnitus or all tinnitus? Sorry just a bit confused.

I’m not even sure how I got tinnitus. Started out of the blue then I ended up having an ear infection/retracted ear drum 2ish weeks later. Wasn’t exposed to loud noises or take ototoxic drugs (I have always been aware of ototoxic drugs since my father lost his hearing in his right ear from cancer treatment a few years back). I don’t even take aspirin etc for headaches. I just drink water. The only pill I ever took which was back in February a few weeks before innitus was amoxicillin/small dose of prednisone. Tinnitus started March 13th or 14th. But I took amoxicillin/prednisone on February 20th.

 

That's good news that your T is not constant. If you protect your ears and give it time to rest maybe you will have less episodes. It's best having not having it constant.