L-Theanine for Tinnitus?

Discussion in 'Alternative Treatments and Research' started by John Bacon, May 7, 2012.

    1. John Bacon

      John Bacon Member

      Tinnitus Since:
      April 2012
      I'm new here. Any comment on L-theanine as treatment?
       
    2. calin
      Inspired

      calin Member Benefactor

      Tinnitus Since:
      Oct 2011
      Hi John! Welcome.

      I have been taking L-theanine regularly for some time. Not a treatment for tinnitus - for me any way.
       
    3. erik
      Breezy

      erik Manager Staff Benefactor

      Location:
      Washington State, USA
      Tinnitus Since:
      04/15/2012
      Cause of Tinnitus:
      Most likely hearing loss
      Been on L-theanine for a few weeks, can't really tell if it works. My T is up and down daily.
       
    4. Danny Boy
      Cheerful

      Danny Boy Member Benefactor Hall of Fame

      Location:
      England
      Tinnitus Since:
      7/2014
      Cause of Tinnitus:
      Ear infection
      "Theanine vs. Xanax? Researchers in Australia compared 200 mg of theanine to 1 mg of Xanax. Subjects were given either theanine, Xanax or a placebo during either a resting task (baseline) or a task that provoked anxiety. Theanine worked better than Xanax to induce relaxation during the resting task, though neither theanine nor Xanax had any significant effects during the anxiety task."

      "Theanine increases serotonin, dopamine, GABA, and glycine levels in various areas of the brain, as well as BDNF and NGF levels in certain brain areas.[15][19][24][25]"

      "Able to cross the blood–brain barrier, theanine has reported psychoactive properties.[28] Theanine has been studied for its potential ability to reduce mental and physical stress"


      L-Theanine (delta-glutamylethylamide) is one of the predominant amino acids ordinarily found in green tea, and historically has been used as a relaxing agent. The current study examined the acute effects of L-theanine in comparison with a standard benzodiazepine anxiolytic, alprazolam and placebo on behavioural measures of anxiety in healthy human subjects using the model of anticipatory anxiety (AA). Sixteen healthy volunteers received alprazolam (1 mg), L-theanine (200 mg) or placebo in a double-blind placebo-controlled repeated measures design. The acute effects of alprazolam and L-theanine were assessed under a relaxed and experimentally induced anxiety condition. Subjective self-reports of anxiety including BAI, VAMS, STAI state anxiety, were obtained during both task conditions at pre- and post-drug administrations. The results showed some evidence for relaxing effects of L-theanine during the baseline condition on the tranquil-troubled subscale of the VAMS. Alprazolam did not exert any anxiolytic effects in comparison with the placebo on any of the measures during the relaxed state. Neither L-theanine nor alprazalam had any significant anxiolytic effects during the experimentally induced anxiety state. The findings suggest that while L-theanine may have some relaxing effects under resting conditions, neither L-theanine not alprazolam demonstrate any acute anxiolytic effects under conditions of increased anxiety in the AA model.

      https://www.ncbi.nlm.nih.gov/pubmed/15378679


      https://pdfs.semanticscholar.org/1005/ab389fa20bbe9b8e18dfd7dc37a80e175e18.pdf
       

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