N-Acetylcysteine (NAC)

Discussion in 'Treatments' started by tweak, May 16, 2012.

    1. gav01

      gav01 Member

      Location:
      U.K.
      Tinnitus Since:
      2003
      Cause of Tinnitus:
      Loud Night club
      I ordered some, I thought that I would go for this before trying Nicotinamide Riboside as both supplements seem to be getting some good feedback but this one is the cheaper of the two.
       
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    2. Allan1967

      Allan1967 Member Benefactor

      Tinnitus Since:
      1997
      Cause of Tinnitus:
      Ear infection
      I've just ordered NAC - 600mg.

      Can someone give me a quick summary of how to take it and how much please?
       
    3. Amv

      Amv Member

      Tinnitus Since:
      16/7/2017
      Cause of Tinnitus:
      -
      Hello Allan, usually the maintenance dose is 600mg. If you suffer noise trauma or want some otoprotection, take 1200mg. For me it upsets my stomach but it is proven in several studies and it is a good medication. Personally and according to my doctor it is good to take breaks from taking it. It helps to get rid of mucus and helps if your ETD is clogged. My only side effect is that it upsets my stomach a lot. Hope this helps!
       
    4. Allan1967

      Allan1967 Member Benefactor

      Tinnitus Since:
      1997
      Cause of Tinnitus:
      Ear infection
      For how long would you take it before taking a break at 600mg a day please? Will it help existing tinnitus?
       
    5. Mystery Reader

      Mystery Reader Member

      Tinnitus Since:
      11/2017
      Cause of Tinnitus:
      Still Under Investigation
      @Allan1967

      Hi,
      I have been thinking of trying this, myself, but confused about all the different brands out there (capsules, tablets, added filler and all that). Out of curiosity, what brand did you buy?
       
    6. vttbx

      vttbx Member Benefactor

      Tinnitus Since:
      01/2001
      I've switched to PharmaNAC from regular NAC caps. You can read some of my old posts on the problems with NAC and oxidation. I think it's worth the extra expense. It's no longer available on Amazon. It also allows me to "stack" acetyl-L-carnitine without any stomach upset. This study was in an old thread:

      https://www.ncbi.nlm.nih.gov/pubmed/15966690
       
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    7. rtlewis88
      Daring

      rtlewis88 Member

      Location:
      Columbia, SC, USA
      Tinnitus Since:
      1980s Concerts Hyperacusis Since: 2015
      Cause of Tinnitus:
      Loud Music and Occupational Hazards as a Young Adult
      I forgot to put this up here; as a series of dosing instructions appear in this article. Moreover, I've been familiar with this (below, listed) limit for close to a week - I saw it on three peer-reviewed journal articles, earlier in the week, when I was trying to determine all that. I have access to all kinds of goodies via my university library coop, but this is a trusted overview which anyone can lookup.

      "General Antioxidant Support
      NAC’s antioxidant actactivities might help to contribute to overall health by reducing the cell damage that sets the stage for a host of diseases. The University of Maryland Medical Center suggests starting with 500 mg daily and slowly increasing with your doctor’s supervision. It reports doses higher than 7,000 mg could cause toxicity."


      RTL
       
    8. Allan1967

      Allan1967 Member Benefactor

      Tinnitus Since:
      1997
      Cause of Tinnitus:
      Ear infection
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    9. gav01

      gav01 Member

      Location:
      U.K.
      Tinnitus Since:
      2003
      Cause of Tinnitus:
      Loud Night club
    10. gav01

      gav01 Member

      Location:
      U.K.
      Tinnitus Since:
      2003
      Cause of Tinnitus:
      Loud Night club
      I’ve never taken NAC before and I took two of these today together at 600mg each and had no problems. I did eat shortly after. I will give them a go without food at some point.
       
    11. gav01

      gav01 Member

      Location:
      U.K.
      Tinnitus Since:
      2003
      Cause of Tinnitus:
      Loud Night club
    12. PureNoise

      PureNoise Member

      Tinnitus Since:
      10/2018
      Cause of Tinnitus:
      Unknown
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    13. ThomasW

      ThomasW Member

      Tinnitus Since:
      February 2019
      Cause of Tinnitus:
      Medication
      I have ototoxic caused tinnitus that has been gradually decreasing since I stopped any meds. I was advised to start taking NAC.

      I started with 600mg in the morning for four days. Then moved to 600mg morning and evening. After 2 days I felt I was having no side effects so I started taking 250mg of ALCAR (Acetyl L-Carnitine), 5 days later, no side effects so I upped the ALCAR dose to 500mg.

      I've been taking 1200mg NAC for 11 days now, 250mg of ALCAR for 5 days and 500mg for 6 days. Its a little early to tell but I do feel its making a difference. My ears aren't as sensitive anymore. I used to have bad periods for several hours where loud noises were sore or annoyed me but I don't recall anything the last week, maybe more. The tinnitus in my right ear has really dropped, if I concentrate really hard it will start up, dumb I know so I won't be doing that again. Left ear is still there but feels like its lowering.

      I don't know if its the NAC and ALCAR or just naturally healing but it is getting quieter and my ears aren't as sensitive to loud harsh noises. I'll finish the bottle and report back.
       
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    14. ChrisBoyMonkey

      ChrisBoyMonkey Member Podcast Patron

      Location:
      CA
      Tinnitus Since:
      04/2019
      Cause of Tinnitus:
      U.S. Army/Field Artillery Veteran
      Where can I buy these?
       
    15. ThomasW

      ThomasW Member

      Tinnitus Since:
      February 2019
      Cause of Tinnitus:
      Medication
      Most pharmacies, health stores and even big supermarket chains will stock these. Just make sure to get a high quality one from a reputable brand.

      I've stopped for the last few days to trial a B Complex supplement. I don't feel any bad side effects so I'll gradually start the NAC and ALCAR again at small doses. Its important to take things slow when trying supplements.
       
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    16. dan26
      Frustrated

      dan26 Member

      Location:
      NJ
      Tinnitus Since:
      1981
      Cause of Tinnitus:
      complete loss of hearing. motorcycle accident
      So 500mg a good place to start. I will look for it soon.
       
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    17. Lilah

      Lilah Member Benefactor

      Location:
      USA
      Tinnitus Since:
      12/2018
      Cause of Tinnitus:
      Unknown, Lupus
      Should I check with a doctor about taking NAC, or is it another harmless supplement like Vitamin C?
       
    18. Lane

      Lane Member

      Tinnitus Since:
      February, 2018
      Cause of Tinnitus:
      Ototoxic Drug
      @Lilah -- From what I can gather, it is pretty harmless. I'm a bit mystified by some of the (undo) concerns regarding supplementing with NAC. I would suggest starting out slow, and if it goes well, gradually increase it, monitoring it as you progress.

      The biggest concern I would have (though it isn't very big) is if it initiated a major detoxification episode. NAC is the go to supplement in ER rooms for when people come in with toxic poisonings of all kinds. The reason for this is because NAC rapidly increases glutathione levels, which is the body's foremost detoxification enzyme.
       
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    19. vttbx

      vttbx Member Benefactor

      Tinnitus Since:
      01/2001
    20. Alue
      No Mood

      Alue Member

      Tinnitus Since:
      01/2016
      Cause of Tinnitus:
      Acoustic Trauma
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    21. vttbx

      vttbx Member Benefactor

      Tinnitus Since:
      01/2001
    22. JudyM
      Frustrated

      JudyM Member

      Location:
      Maryland
      Tinnitus Since:
      05/2019
      Cause of Tinnitus:
      unknown
      Quick but important question for anyone who has knowledge. I have noticed NAC supplements are being used extensively for tinnitus.

      I read somewhere, on another site, that it should not be used if you have amalgams.

      Does anyone here have any first hand knowledge about this information?
       

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