New University of Michigan Tinnitus Discovery — Signal Timing

Discussion in 'Research News' started by Hudson, Jun 20, 2013.

    1. annV
      Fine

      annV Member

      Tinnitus Since:
      2005
      Cause of Tinnitus:
      unknown - possibly hereditary
      https://clinicaltrials.gov/ct2/show/NCT03621735

      Actual Study Start Date : November 1, 2018
      Estimated Primary Completion Date : September 2022
      Estimated Study Completion Date : January 2023

      So a long way off!
       
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    2. Stefaniie

      Stefaniie Member

      Tinnitus Since:
      2017
      Cause of Tinnitus:
      Hereditary hearing loss/noise exposure
      Oh yikes! Here's to hoping the Lenire device works.
       
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    3. KotaDomowa
      Dreaming

      KotaDomowa Member

      Location:
      Poland
      Tinnitus Since:
      Februar 2018
      Cause of Tinnitus:
      Unknown
      I may be wrong, but I think that none of the other two bimodal projects will come out on the market before 2025.
       
    4. DaveFromChicago

      DaveFromChicago Member

      Tinnitus Since:
      01/2014
      Cause of Tinnitus:
      Headcold/Flu
      How sadly ironic that my previous facetious comments about how the Glaciers formed the Great Lakes in less time than it is taking for certain research institutions to release an effective treatment is actually accurate.

      As annV indicated, let's anticipate that the combined technology that created Lenire will be sufficient as a treatment.
       
    5. KMc24

      KMc24 Member Benefactor

      Tinnitus Since:
      3/2018
      Cause of Tinnitus:
      Noise induced
      With the number of companies working on hearing restoration and tinnitus treatments, Dr. Susan Shore might find herself to be completely irrelevant by then. Unless she's got something up her sleeve it seems Neuromod has already beat her to the punch anyway.
       
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    6. jeas

      jeas Member Benefactor

      Tinnitus Since:
      October 25, 2018
      Cause of Tinnitus:
      TMJ/Neck
      I emailed Dr. Shore about this trial, hoping to maybe get in. She said that they plan to begin commercialization next year.

      Just thought I would pass this along.
       
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    7. Bndsmheowqhe

      Bndsmheowqhe Member

      Tinnitus Since:
      2016
      Cause of Tinnitus:
      Loud noise exposure
      I thought that was the timeline they were operating on. If that's the case they have a good shot at competing with Neuromod. If I had to choose between the the two I would rather plunk down the $3000 on Shore's device.
       
    8. Manny
      Dead

      Manny Member Benefactor Hall of Fame

      Location:
      United States
      Tinnitus Since:
      1/2018
      Cause of Tinnitus:
      central gain << NIHL
      Do you know if that means as in having a clinic for patients up and running next year (I doubt it...), or just some sort of step towards commercialization?
       
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    9. Bndsmheowqhe

      Bndsmheowqhe Member

      Tinnitus Since:
      2016
      Cause of Tinnitus:
      Loud noise exposure
      From what I've read in the past they want to bring it to market in 2020.
       
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    10. ChrisBoyMonkey

      ChrisBoyMonkey Member Podcast Patron

      Location:
      CA
      Tinnitus Since:
      04/2019
      Cause of Tinnitus:
      U.S. Army/Field Artillery Veteran
      Whoooaaaaaaaaa that's crazy good news. Awesome find!
       
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    11. Don Tinny

      Don Tinny Member

      Location:
      Argentina
      Tinnitus Since:
      2017 (worsening)
      Cause of Tinnitus:
      Loud concert with ear plugs
      Sadly there is no information about the effectiveness of this device in cases of non-somatic tinnitus. I asked her some time ago and she answered "We don't know, but it might work".
       
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    12. Ken219
      Frustrated

      Ken219 Member

      Location:
      New York Area
      Tinnitus Since:
      Summer of 1990
      Cause of Tinnitus:
      Noise exposure?
      P.T. Barnum
      “The public appears disposed to be amused even when they are conscious of being deceived.”
      "There's a sucker born every minute"
       
    13. jeas

      jeas Member Benefactor

      Tinnitus Since:
      October 25, 2018
      Cause of Tinnitus:
      TMJ/Neck
      The way I read it was that she planned on it being on the market next year. But I could be wrong.

      I never asked her when she thought her device would be on the market, she added that in to her response on her own. So I hope this is promising news.
       
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    14. linearb
      Psychedelic

      linearb Member Benefactor Hall of Fame

      Location:
      temporarily banished from this plane of existence.
      Tinnitus Since:
      1999
      Cause of Tinnitus:
      karma
      they have consistently said they're targeting 2020-2022 for first commercialization, pending FDA approval and completion of parts of the Phase-II.

      Current phase-II will not complete until later than that but I was told early on that would not necessarily be an impediment to market.
       
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    15. jeas

      jeas Member Benefactor

      Tinnitus Since:
      October 25, 2018
      Cause of Tinnitus:
      TMJ/Neck
      Makes sense. Thank you!
       
    16. jmasterj
      No Mood

      jmasterj Member Benefactor

      Tinnitus Since:
      2011
      Cause of Tinnitus:
      Acoustic?
      This is interesting news. I have always been hoping that Susan would get the credit she deserves for all her work.

      My hope was always to go with her device, but it seems to be moving slow. I am still going to keep my appointment with Neuromod. I will be curious how she gets FDA approval without finishing the trials. I do know that they are less stringent on medical devices versus drugs.
       
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    17. Jack Straw
      Balanced

      Jack Straw Member Podcast Patron Benefactor Ambassador Hall of Fame Advocate

      Location:
      US
      Tinnitus Since:
      1990s
      Cause of Tinnitus:
      Infection, Acoustic Trauma
      There seems to be so much conflicting information regarding commercialization of their device. Some people say that they talked with her and she said commercialization will start next year, others based on trial information say as late as 2023.
       
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    18. Fabrikat

      Fabrikat Member

      Tinnitus Since:
      1973
      Cause of Tinnitus:
      Otosclerosis then volume then viral infection
      Are you able to post her email reply to you?
       
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    19. jeas

      jeas Member Benefactor

      Tinnitus Since:
      October 25, 2018
      Cause of Tinnitus:
      TMJ/Neck
      Sure.

      "We are currently running a trial. If you live within 100 miles of Ann
      Arbor you may be eligible. We hope to begin commercialization next year.

      I can't comment on Lenire as they haven't published any controlled
      clinical trials.

      Best wishes,

      Susan Shore"
       
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    20. Bndsmheowqhe

      Bndsmheowqhe Member

      Tinnitus Since:
      2016
      Cause of Tinnitus:
      Loud noise exposure
      I have a good feeling about this.
       
    21. Candy

      Candy Member Benefactor Advocate

      Tinnitus Since:
      06/2016
      Cause of Tinnitus:
      Unidentified
      Next year, I thought it was 2023??? I think I would be a good candidate for this method given I have no hearing loss...
       
    22. jeas

      jeas Member Benefactor

      Tinnitus Since:
      October 25, 2018
      Cause of Tinnitus:
      TMJ/Neck
      Hey! Could you PM me? I tried to PM you but it wouldn't let me.
       
    23. Martin69
      Artistic

      Martin69 Member Benefactor

      Location:
      Germany
      Tinnitus Since:
      10/2013
      Cause of Tinnitus:
      (Health) Anxiety
      Do we know if anyone from Tinnitus Talk is taking part in the trial?

      @Markku
       
    24. hurtingdream

      hurtingdream Member Benefactor

      Location:
      Michigan, USA
      Tinnitus Since:
      01/2002
      Cause of Tinnitus:
      Unknown/ETD since 11/2015
      Susan Shore e-mailed me back yesterday and she said her audiologist will contact me next week to see if I am eligible. I am pregnant so I hope that doesn't exclude me.
       
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    25. linearb
      Psychedelic

      linearb Member Benefactor Hall of Fame

      Location:
      temporarily banished from this plane of existence.
      Tinnitus Since:
      1999
      Cause of Tinnitus:
      karma
      Interesting that she said, "within 100 miles", and not "within 100 miles or willing to travel". I did the latter, it was a nice excuse to spend a bunch of weeks in Ann Arbor which is a pretty cool little city.
       
    26. Candy

      Candy Member Benefactor Advocate

      Tinnitus Since:
      06/2016
      Cause of Tinnitus:
      Unidentified
      Things are going to become expensive for me, first Lenire, then Susan Shore's device... mmmhhh decisions.
       
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    27. dayma
      Frustrated

      dayma Member Benefactor

      Tinnitus Since:
      1/6/2018
      Cause of Tinnitus:
      UNKNOWN
      I got a similar email.
       
    28. steyrs
      Pacman

      steyrs Member

      Location:
      Denmark
      Tinnitus Since:
      07/2015
      Cause of Tinnitus:
      Dental care - got teeth cleaned with ultrasound
      At least it is two remedies that might be able to relieve you from hell - and not stupid moronic stuff like ear candles
       
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    29. Paulmanlike

      Paulmanlike Member Hall of Fame

      Tinnitus Since:
      2008
      Cause of Tinnitus:
      Noise
      Shore's device has been used on 20 patients with only somatic tinnitus... (and claiming, it so seems, to be on the market next year based on 20 people??)

      Neuromod's device has been used on over 500 people with rigorous clinical trials and been submitted for peer review

      I would seriously want to see the evidence before parting with a couple thousand... I know what desperation does to one suffering but there’s nothing worse than buying things to be disappointed you’ve been conned (not saying it’s a con - but more trials are needed to build an evidence base and likelihood of it working).
       
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    30. Chinmoku

      Chinmoku Member Benefactor

      Tinnitus Since:
      10/2018
      Cause of Tinnitus:
      Unknown, possibly medication
      Agreed, you would think that something that is priced at 2500 EUR would be supported by published clinical evidence. Granted, we have seen much worse in the past, with expensive treatments having zero or very little evidence. At least Neuromod seems to have done a lot of work, even if they started commercialisation before the review publication. I still believe that asking people to pay 2500 EUR before you publish the evidence only works because people are desperate for relief, and I perfectly understand that, but in an ideal world Neuromod would have published the review before the commercialisation. Oh well, in an ideal world there would be no tinnitus.
       
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