PSA: Avoid Certain Ototoxic Antibiotics — They Can Cause Tinnitus / Hearing Loss

Discussion in 'Support' started by Pat Grann, May 24, 2021.

    1. Pat Grann

      Pat Grann Member

      Tinnitus Since:
      1963
      Cause of Tinnitus:
      Military - Loud Noise
      Some antibiotics are ototoxic.

      Ototoxicity is the property of being toxic to the ear (oto-), specifically the cochlea or auditory nerve and sometimes the vestibular system, for example, as a side effect of a drug. The effects of ototoxicity can be reversible and temporary, or irreversible and permanent. Ototoxic drugs can damage your ears, cause hearing loss and tinnitus.

      I have had tinnitus for almost 50 years.

      I made the mistake of taking Ciprofloxacin for a UTI. I also told the doctor beforehand that I needed a drug that wasn't ototoxic. After I started taking Ciprofloxacin, I noticed a decline in my hearing and an increase in my tinnitus level.

      Now my hearing loss has improved a little but my tinnitus has not.

      Don't take any antibiotic ending in "CIN". Much is discussed about what to take for tinnitus, but not enough about what NOT to take.

      I have some excellent advice for people who have had tinnitus for a short while. Your brain will become partially DESENSITIZED and accept the tinnitus where you will not feel as bad. It took me many years but my brain did partially learn to accept the tinnitus. That's some hope that doctors never tell you.
       
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    2. Wrfortiscue
      Provocative

      Wrfortiscue Member

      Tinnitus Since:
      1999
      Cause of Tinnitus:
      Trauma
      Is it just random that people get tinnitus from antibiotics?
       
    3. serendipity1996
      No Mood

      serendipity1996 Member Podcast Patron Hall of Fame

      Tinnitus Since:
      2011 - T, 2016- H, relapsed 2019
      Cause of Tinnitus:
      noise-induced
      Certain antibiotics are documented as ototoxic - particularly the aminoglycoside class (typically ending in 'mycin') which tend to be the worst offenders. Azithromycin, from the macrolide class, has also led to cochlear damage in rare cases, and the fluoroquinolones (e.g Ciprofloxacin and Levaquin) can also cause damage. The fluoroquinolones carry a black-box warning now as there is a risk of severe multi-system side effects e.g tendon rupture.

      I've personally been on Nitrofurantoin, Trimethoprim, and Amoxicillin with no issues and I think they are generally considered pretty low-risk.
       
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    4. Bimmerboy

      Bimmerboy Member

      Location:
      London
      Tinnitus Since:
      14/02/21
      Cause of Tinnitus:
      covid, infection, stress, ototoxic meds, noise, TMJ
      @serendipity1996, my tinnitus was caused by Neomycin ear drops. It's a shame doctors give out such medicine, without knowing it can cause side effects such as tinnitus and hyperacusis.
       
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    5. Steph1710
      Old hag

      Steph1710 Member Podcast Patron Benefactor Ambassador Hall of Fame

      Location:
      England
      Tinnitus Since:
      08/04/2020
      Cause of Tinnitus:
      Antibiotics - I think
      My tinnitus was caused by antibiotics.
       
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    6. Wrfortiscue
      Provocative

      Wrfortiscue Member

      Tinnitus Since:
      1999
      Cause of Tinnitus:
      Trauma
      Oh yeah? What kind and how long were you taking them? Has your tinnitus improved at all over time?
       
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    7. Wrfortiscue
      Provocative

      Wrfortiscue Member

      Tinnitus Since:
      1999
      Cause of Tinnitus:
      Trauma
      Are you referring to oral or ear drop Ciprofloxacin?

      I took Ciprofloxacin months ago, but ear drops. I didn't have a perforated eardrum though.
       
    8. Steph1710
      Old hag

      Steph1710 Member Podcast Patron Benefactor Ambassador Hall of Fame

      Location:
      England
      Tinnitus Since:
      08/04/2020
      Cause of Tinnitus:
      Antibiotics - I think
      Yup. And tinnitus is actually listed in the top ten side effects. Never had tinnitus before. Then after six months of taking it, I started having loads of fleeting tinnitus - until one morning, I woke up, and it never disappeared.

      I was taking Doxycycline.

      Yes, it has improved, but it will never go. The damage is done unfortunately. But never mind - onwards and upwards! :)
       
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    9. Wrfortiscue
      Provocative

      Wrfortiscue Member

      Tinnitus Since:
      1999
      Cause of Tinnitus:
      Trauma
      That sucks. Glad you’re coping though. My tinnitus was the best yesterday, but spiked double for no reason last night and it hasn’t gone down since then. I haven’t had a spike last this long from the COVID-19 vaccine. Only thing I did was walk with Decibullz earplugs. I could hear the wind though.
       
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    10. Tweedleman
      Depressed

      Tweedleman Member Benefactor

      Location:
      Canada
      Tinnitus Since:
      2001
      Cause of Tinnitus:
      Unknown/Noise
      Omg my homie, you had to take that nastiness for 6 months? That's awful. Sounds like your ears put up a hell of a fight at least! I always hear about people getting it after even only a short round of antibiotics.

      I love your attitude, onwards and upwards indeed! Although, in my case, it's probably onwards but not necessarily upwards. Nevertheless, full speed ahead! :woot:
       
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    11. Steph1710
      Old hag

      Steph1710 Member Podcast Patron Benefactor Ambassador Hall of Fame

      Location:
      England
      Tinnitus Since:
      08/04/2020
      Cause of Tinnitus:
      Antibiotics - I think
      Hey buddy! Yeah :( I was put on it to help with progressive dry eye - unfortunately it didn’t do shit to help my eyes, but it did give me tinnitus instead... yay! :banghead:
      I remember getting the fleeting tinnitus quite soon after taking it. I looked in the side effects and saw tinnitus listed in the ten most common. Unfortunately I was under the illusion that if I stopped taking it, the side effects would go. I had no idea that tinnitus could be permanent!

      I remember waking up one morning and asking what that annoying sound was? It then hit me, that I had permanent tinnitus. I stopped the Doxycycline straight away, but the damage was done.
      Tbh, we don’t have much choice haha! I would prefer to carry on, rather than give up.
      I don’t doubt that for a second ;) Let’s enjoy this crazy ride!
       
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    12. Wrfortiscue
      Provocative

      Wrfortiscue Member

      Tinnitus Since:
      1999
      Cause of Tinnitus:
      Trauma
      I want your attitude.
       
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    13. Steph1710
      Old hag

      Steph1710 Member Podcast Patron Benefactor Ambassador Hall of Fame

      Location:
      England
      Tinnitus Since:
      08/04/2020
      Cause of Tinnitus:
      Antibiotics - I think
      Well I have something I call the “fuck it” button.

      When life gets super shit, or problems occur, I press it and say “FUCK IT”. Then I move on with things lol.

      Anyway, you’re welcome to use the “fuck it” button - it’s free to anyone.

      :)
       
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    14. Wrfortiscue
      Provocative

      Wrfortiscue Member

      Tinnitus Since:
      1999
      Cause of Tinnitus:
      Trauma
      Whatever works, I’m in.
       
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    15. linearb
      Psychedelic

      linearb Member Benefactor Hall of Fame

      Location:
      beliefs are makyo and reality ignores them
      Tinnitus Since:
      1999
      Cause of Tinnitus:
      karma
      Fluoroquinolone antibiotics (of which Ciprofloxacin is one) are absolutely some of the most dangerous drugs commonly prescribed and are, IMO, criminally overused. I believe they should only be used in the case of a clearly cultured pathogen which is treatment resistant to other drugs, or as a last ditch effort in the case someone is septic/etc.

      The fact they're routinely given out for stuff like sinus infections (which are almost always viral, and therefore antibiotics do nothing) is just insane to me. These drugs are known to cause random tendon ruptures and neurological damage similar to what benzodiazepine withdrawal can cause if handled incorrectly.

      I've only "fired" two doctors in my life, and one was a Primary Care doctor who really wanted me to take Ciprofloxacin for something that probably wasn't even bacterial. When I just refused, she responded by writing me a script for Levaquin (an even MORE dangerous drug in the same class) and suggested that if I didn't want to take it I should find a new healthcare provider. I fucking did, that day.
       
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    16. linearb
      Psychedelic

      linearb Member Benefactor Hall of Fame

      Location:
      beliefs are makyo and reality ignores them
      Tinnitus Since:
      1999
      Cause of Tinnitus:
      karma
      We can't go on this because antibiotic naming is weird. A lot of the macrolides (Erythromycin, Z-Paks) end in `cin` and even though these drugs can very very rarely cause audiological impacts, they are almost always fleeing, generally regarded as safe, and if you search this forum for Z-Pak etc IIRC you find more people who had zero effect or a temporary effect on their tinnitus, than any long term problems.

      Fluoroquinolones do all end in `cin` as far as I know and the common ones to watch out for are Ciprofloxacin (Cipro), Levofloxacin (Levaquin), Moxifloxacin. These are on the list of drugs I tell providers I have had a severe reaction to in the past and am unwilling to take barring massive obvious medical necessity.

      Doxycycline ends `ine` and is generally considered safe but has a few more unhappy anecdotes about tinnitus than I am generally comfortable with. I do take this when I have potential Lyme exposure from ticks, I also work like hell to avoid getting ticks, I'd rather bathe in Permethrin than take Doxycycline after the fact. Ticks are gross.

      Some of the `mycin` ending antibiotics are not great for the ears but user reports seem to vary a lot and IV use seems much more.

      By far the worst for the ears are probably the aminoglycosides which end in `micin` (not i vs y), common drugs here are Gentomycin and Streptomycin. I have never taken any drug in this class so I can't speak to them, except that their ototoxicity is probably better documented than anything else here.

      @Pat Grann, sorry this happened; I would be hopeful things will continue to improve, and maybe take some gentle supporting supplements like Magnesium glycinate.
       
    17. Wrfortiscue
      Provocative

      Wrfortiscue Member

      Tinnitus Since:
      1999
      Cause of Tinnitus:
      Trauma
      Geez, is anything safe these days? Now I’m worried for my son lol. He had to use antibiotic ear drops when he was younger and that’s with ear tubes.
       
    18. Jebbis
      Dancing

      Jebbis Member

      Location:
      United states
      Tinnitus Since:
      September 2020
      Cause of Tinnitus:
      Unknown, I suspect stress/smoking/tmj/neck issues
      Ugh... A few years back, i had a time where I was having chronic UTIs. I had like 7 in 6 months, which is more than 1 infection per month. That also meant 6 rounds of different antibiotics, and when those didn't work, they put me on a month long round to kill off the bacteria. (Little did I know, stupid me was eating contaminated cheap chicken from Costco, causing the infections. Yuck.)

      There was one antibiotic that gave me a rash and made me puke. I think the month long dose might've been Amoxicillin, I'm not sure. I'm allergic to Penicillin and Nitrofurantoin (or however you spell it). I wonder if my many experiences with antibiotics made my ears sensitive. I also had chronic ear infections as a baby. I'm the perfect patient!

      Also for the record, I would 100% rather have tinnitus than chronic bladder infections. I was constantly afraid the infection would reach my kidneys. Peeing felt like knives. I couldn't sleep because of the pain, couldn't eat because of the antibiotics... I know tinnitus sucks so bad, but chronic painful internal infection is a different level of discomfort.
       
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