Antidepressants (SSRIs, SNRIs, MAOs, TCAs, TeCAs)

Discussion in 'Treatments' started by Pat, May 10, 2012.

    1. makeyourownluck
      Magical

      makeyourownluck Member Podcast Patron Benefactor Hall of Fame

      Location:
      Scotland
      Tinnitus Since:
      07/2021
      Cause of Tinnitus:
      Unknown
      Duloxetine - complete game changer.
       
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    2. Nick47

      Nick47 Member Benefactor

      Location:
      UK
      Tinnitus Since:
      2015
      Cause of Tinnitus:
      Viral/noise
      He added 2.5 mg of Aripiprazole to my script. This seems like something he started doing 18-24 months ago. He recommended adding a bit of Cyclobenzaprine if you have somatic tinnitus and if that's not enough, LDN. His premise is that these on their own won't help much but by combining them they might.
       
    3. gameover

      gameover Member Benefactor

      Location:
      USA
      Tinnitus Since:
      2023
      Cause of Tinnitus:
      Noise+sinus
      So there are these studies that talk about antidepressants "rewiring the brain", suggesting permanent changes:

      Antidepressants can rewire the human brain, study reveals

      This kinda further supports the idea that antidepressants are Russian roulette in general, but particularly so with tinnitus. No surprise why often tinnitus (or a spike) does not go away after stopping these drugs. Permanent changes were made, done deal.
       
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    4. ErikaS

      ErikaS Member Benefactor Hall of Fame

      Location:
      Pennsylvania, USA
      Tinnitus Since:
      09/2022
      Cause of Tinnitus:
      Ear infection/Ultra High Frequency SSHL in Right Ear
      I feel like you are the 2nd or 3rd person on Tinnitus Talk that have stated Duloxetine (Cymbalta) was a game changer. I brought this med up with my psychiatrist two weeks ago and he was "hesitant" about SNRIs.
       
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    5. Loui

      Loui Member Benefactor

      Location:
      Sweden
      Tinnitus Since:
      06/2018
      Cause of Tinnitus:
      Noise induced
      Thank you for your response. It’s helpful to get input from another tinnitus sufferer. I think I’ll postpone the antidepressant route for now. It feels kind of scary to be on a medication long term. Also, it appears the understanding of how antidepressants work is lacking.

      I’ll continue trying to manage the tinnitus by cold plunges, exercising, and spending time in nature. Let’s hope Dr. Shore’s device is a success so we can get some relief in a couple of years.

      Right now I’m kind of in the hamster wheel of work, workout, eat, sleep repeat. But I’ll at least take two weeks’ holiday this summer.
       
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    6. makeyourownluck
      Magical

      makeyourownluck Member Podcast Patron Benefactor Hall of Fame

      Location:
      Scotland
      Tinnitus Since:
      07/2021
      Cause of Tinnitus:
      Unknown
      Obviously there are risks. If I wasn’t completely desperate, I probably wouldn’t have taken it, but it really has helped me. I’ve gone from being in pain, lying in bed basically all day, to baking cakes with my little girl and managing my physio every day.

      A few months ago I was really far gone, completely numb to everything, like on a different planet. Couldn’t even muster the energy to reply to people on here.
      Fair enough, tinnitus makes meds a bit of a minefield unfortunately. I actually just started doing ice baths, it’s brutal when you’re in the water, but helps a lot with pain. I don’t think it’s had any impact on tinnitus though.

      I hope you get a bit of time for yourself over the summer to recharge the batteries.
       
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    7. AfroSnowman
      Balanced

      AfroSnowman Member Hall of Fame

      Tinnitus Since:
      04/2019
      Cause of Tinnitus:
      Nonnatural energy source
      I tried it for a few weeks, I stopped when I started getting essential tremors. Like I couldn’t use a spoon any more and writing was challenging. It took a couple weeks for my hands to stop shaking when I stopped. Long term all side effects went away. Kind of scared me though.
       
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    8. gameover

      gameover Member Benefactor

      Location:
      USA
      Tinnitus Since:
      2023
      Cause of Tinnitus:
      Noise+sinus
      I am reinforced in my belief that antidepressants are the devil's pills. Here are a few short, worthwhile videos to watch. These people are not quacks.

      Dr. Peter Breggin: ¿tiene usted un...


      Psychiatric drugs are incredibly destructive...


      There’s No Such Thing as an...
       
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    9. blamingeverything

      blamingeverything Member Benefactor

      Location:
      USA
      Tinnitus Since:
      12/2021
      Cause of Tinnitus:
      high frequency hearing loss
      I think I might give Cymbalta a shot. I will report back if I do.
       
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    10. Nick47

      Nick47 Member Benefactor

      Location:
      UK
      Tinnitus Since:
      2015
      Cause of Tinnitus:
      Viral/noise
      What on earth are you going on about?
       
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    11. Strawberryblonde
      Cheerful

      Strawberryblonde Member Hall of Fame

      Location:
      UK
      Tinnitus Since:
      1st mild (6/12/2015) mild-mod (3/5/2022)
      Cause of Tinnitus:
      HEADPHONES/TMJ/ETD/SINUSES one of them???
      Because you found 3 videos? As much as antidepressants do cause issues with people, they also pull people back from the edge, allowing them to maintain some kind of normality in their life. It's unfortunately 50/50 with antidepressants; you either risk using them for benefit, or you don't. Each to their own.
       
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    12. Nick47

      Nick47 Member Benefactor

      Location:
      UK
      Tinnitus Since:
      2015
      Cause of Tinnitus:
      Viral/noise
      I'm all for people's experiences, good or bad, but ranting and screaming things like 'poison' or 'the devil' offers nothing. These same people will then be happy for XEN1011 or any other medication to treat their tinnitus. Some of these people down alcohol and eat processed foods.
       
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    13. makeyourownluck
      Magical

      makeyourownluck Member Podcast Patron Benefactor Hall of Fame

      Location:
      Scotland
      Tinnitus Since:
      07/2021
      Cause of Tinnitus:
      Unknown
      I hope it helps. As I said, it’s been brilliant for me. At this point it’s looking like a sustained improvement - contemplating upping my dose also. I will update you all on the outcome if I do.
       
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    14. blamingeverything

      blamingeverything Member Benefactor

      Location:
      USA
      Tinnitus Since:
      12/2021
      Cause of Tinnitus:
      high frequency hearing loss
      I appreciate you sharing your experience. What dose are you on now?
       
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    15. gameover

      gameover Member Benefactor

      Location:
      USA
      Tinnitus Since:
      2023
      Cause of Tinnitus:
      Noise+sinus
      Did you watch those videos I linked above? Antidepressants can at times help. The help can be short lived, and may lead to more problems. For people with tinnitus, it's a Russian roulette. I think people going on antidepressants should be aware of the risks. Ultimately it's one's own decision. Doctors are happy to prescribe this stuff because they will not bear the consequences.
      Sure. 50/50 are pretty poor odds in my book, YMMV.
       
    16. makeyourownluck
      Magical

      makeyourownluck Member Podcast Patron Benefactor Hall of Fame

      Location:
      Scotland
      Tinnitus Since:
      07/2021
      Cause of Tinnitus:
      Unknown
      No worries, I’m on 60 mg.

      I took 20 mg for 2 weeks (ish), 30 mg for a week, now I’ve been on 60 mg for 4 weeks. I started to see a difference on week 4, so 1 week after taking 60 mg.

      I will talk about potential increase with my doctor next Friday and report back.
       
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    17. Nick47

      Nick47 Member Benefactor

      Location:
      UK
      Tinnitus Since:
      2015
      Cause of Tinnitus:
      Viral/noise
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    18. makeyourownluck
      Magical

      makeyourownluck Member Podcast Patron Benefactor Hall of Fame

      Location:
      Scotland
      Tinnitus Since:
      07/2021
      Cause of Tinnitus:
      Unknown
      1. Reduced pain significantly
      2. Evened out my mood so I can cope with pain flares
      3. Given me a general sense of well-being, sometimes borders in euphoria
      4. Sex drive is back
      5. More energy throughout the day
      6. Given me an over all sense of ‘ok, you got this’ instead of ‘omg, my life is over’
      Probably more benefits that I can’t think of :) Yeah, it’s been night and day really. Nightmares are the only issue - very intense and realistic dreams.
       
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    19. blamingeverything

      blamingeverything Member Benefactor

      Location:
      USA
      Tinnitus Since:
      12/2021
      Cause of Tinnitus:
      high frequency hearing loss
      That's really great. I tend to be a very sensitive person (imagine that, being here), and range from debilitatingly anxious to depressed to being rather normal. My sleep suffers greatly. I really need something to even me out so I don't resort to taking more Clonazepam over time.
       
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    20. makeyourownluck
      Magical

      makeyourownluck Member Podcast Patron Benefactor Hall of Fame

      Location:
      Scotland
      Tinnitus Since:
      07/2021
      Cause of Tinnitus:
      Unknown
      Yeah, I’m the exact same in terms of how varied my moods can be. Since starting Duloxetine, I’ve noticed a huge difference and so have the people around me. I’m just generally a bit happier I suppose. Up and about etc.

      I had a few realisations too which I’m now sorting out - decided to take some time completely off work. Focus on getting better.
       
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    21. Nick47

      Nick47 Member Benefactor

      Location:
      UK
      Tinnitus Since:
      2015
      Cause of Tinnitus:
      Viral/noise
      Tinnitus/hyperacusis doesn't seem to be your main issue?
       
    22. makeyourownluck
      Magical

      makeyourownluck Member Podcast Patron Benefactor Hall of Fame

      Location:
      Scotland
      Tinnitus Since:
      07/2021
      Cause of Tinnitus:
      Unknown
      No, my main issue is chronic nerve pain. My tinnitus has been fine though. If anything I’m finding it easier to deal with.
       
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    23. makeyourownluck
      Magical

      makeyourownluck Member Podcast Patron Benefactor Hall of Fame

      Location:
      Scotland
      Tinnitus Since:
      07/2021
      Cause of Tinnitus:
      Unknown
      OK guys, last night I upped my Duloxetine dose to 90 mg. My doctor originally suggested going from 60 mg to 120 mg but I’m being a bit more cautious. I will do 90 mg for 2 weeks and then go up to 120 mg. I will keep you all posted on how my ears are fairing.
       
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