Hough Ear Institute's Hair Cell Regeneration Project

Discussion in 'Research News' started by all to gain, Oct 2, 2019.

    1. SmallRonnie
      Ape-like

      SmallRonnie Member Podcast Patron Benefactor

      Location:
      Ireland
      Tinnitus Since:
      2021
      Cause of Tinnitus:
      Factory noise + Headphones + Clubbing + Vaccine? + Stress
      This isn't the only company to be slowing down now. The cost of short term loans for businesses in the US is absolutely skyrocketing. That and inflation is still very high so the cost of carrying out the trials is now much higher than they first would have expected.

      Maybe that's not the reason but it's one possible reason.
       
      • Agree Agree x 1
    2. Nobody19

      Nobody19 Member Benefactor

      Tinnitus Since:
      2012
      Cause of Tinnitus:
      Clubbing
      Their Phase one trial was finished back in 2015. The current inflation and interest rate rises didn't cause companies from picking up the drug back then. They were even ahead of Frequency Therapeutics.

      I agree, something is very fishy here. I feel bad for all the people who donated to them. Other researchers could have benefited from that money.

      @Moderators, I think you seriously need to consider removing Hough Ear Institute from the worthy causes list. There has been 0 progress in 7 years.
       
      • Agree Agree x 6
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    3. ThomasF
      Creative

      ThomasF Member

      Location:
      Florida
      Tinnitus Since:
      2001
      Cause of Tinnitus:
      Probably loud music
      I'm honestly a little scared this isn't going anywhere. There's been very little information out there on this drug for as long as it's been around. Oblato not fulfilling the compassionate use could be economic but if that's the case, the same can be said for other companies. Hopefully this just means Hough Ear Institute will go through other methods of testing for Phase 2 and we'll get a definitive answer on it being effective or not. I'm still holding out positively for good things in the future but I'm sinking my hopes for compassionate use.
       
      • Agree Agree x 3
    4. Nick47

      Nick47 Member

      Tinnitus Since:
      2015
      Cause of Tinnitus:
      Viral/noise
      You know when you are over the target. I asked on Hough Ear Institute's Facebook page if there was any literature to read that their pill could treat 'chronic' tinnitus.

      I was removed and now cannot see the Facebook page.

      Mention the word CHRONIC to them and watch them self implode.

      Those guys leave a really sour taste in the mouth. Justin De Moss creeping on here looking to fleece people by misleading them. Maybe America is different, but in the UK a 'non-profit' organisation behaving like that would be outed quickly.

      Surely whether government or donations, it's OUR tax payer money?

      Private biotechs acting like this I could understand at least.
       
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    5. KoolKat

      KoolKat Member

      Location:
      USA
      Tinnitus Since:
      2013
      Cause of Tinnitus:
      HeadPhones/ Noise induced
      Are you serious man, WTF. Come on :banghead:
       
      • Agree Agree x 1
    6. Brian Newman

      Brian Newman Member

      Tinnitus Since:
      12/2016
      Cause of Tinnitus:
      Shooting/loud noise
      :wacky: Lol, let’s give a drug that would potentially help a lot of people to just one person, give other people hope they will get it too, then shut everything down and say screw you, nobody else gets it. But then let’s have the one guy speak at an event about how it helped him and rub it in all our faces. I can’t, I just can’t. It actually makes me laugh thinking about how amazing Hough Ear Institute and Oblato are.

      I can’t make it up everybody, this is real life. Its almost 2023 and there’s nothing for hearing damage yet. Ugh, I’m not a negative person when it comes to this stuff, but my god this stinks.
       
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    7. Hottopic29

      Hottopic29 Member Benefactor

      Location:
      Niagara falls
      Tinnitus Since:
      11/2013
      Cause of Tinnitus:
      Zithromycin acoustic trauma 2022
      Are we sure it worked for that person? Maybe they are going to say it made no difference.
       
    8. Nick47

      Nick47 Member

      Tinnitus Since:
      2015
      Cause of Tinnitus:
      Viral/noise
      You think they are going to put someone up to say it doesn't work?

      Really?

      That will attract a biotech for sure :-/
       
    9. ajc

      ajc Member

      Tinnitus Since:
      11/2002; spike 2009; worse 2017-18
      Cause of Tinnitus:
      Loud music - noise damage
      Yeah, even Hough Ear Institute would not be stupid enough to have a patient testimonial saying "nope, didn't work" :ROFL:
       
      • Agree Agree x 1
    10. Brian Newman

      Brian Newman Member

      Tinnitus Since:
      12/2016
      Cause of Tinnitus:
      Shooting/loud noise
      Yeah, I don’t think they would have him come speak at an event if if didn’t work for him, tbh.
       
    11. star-affinity
      Wishful

      star-affinity Member Podcast Patron Benefactor

      Tinnitus Since:
      1993, increase in 2020, then new in 2021
      Cause of Tinnitus:
      Unsure about the first. Too many beers? Music during sleep.
      Another email sent out by Hough Ear Institute contains this story by tinnitus sufferer Scott. At the end:

      ”I am a rather skeptical person by nature, but from what I’ve learned of HEI’s progress with NHPN-1010, the future for me (and for so many others) looks a lot brighter.”

      (Source)

      Please be true. :nailbiting:
       
      • Informative Informative x 4
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    12. Nick47

      Nick47 Member

      Tinnitus Since:
      2015
      Cause of Tinnitus:
      Viral/noise
      @star-affinity, please what be true exactly?
       
    13. BrysonKingMe

      BrysonKingMe Member

      I haven't been keeping up with this at all.

      Can someone catch me up to speed on what types of tinnitus this will work for? Only noise induced?

      Is there a timeline when this will be available outside of compassionate use?
       
      • Good Question Good Question x 1
    14. Brian Newman

      Brian Newman Member

      Tinnitus Since:
      12/2016
      Cause of Tinnitus:
      Shooting/loud noise
      Lol, Hough Ear Institute are claiming NHPN-1010 will give people complete silence. Does that make anybody else laugh? I’m sorry, I’m going to keep saying this, and many will agree; any drug that would completely cure tinnitus, would take 8 years just to get to Phase 2. They were making all these claims and statements 6 years ago in 2016 when I got tinnitus. 6 years later nothing has budged. Hey, I understand they are a private company and need funding, but I don’t know, if the drug worked as well as they say it does, there would be no issue to find more funding. And they did get $2 million from the government a while back too.

      Hey, I’m all for optimism, but this is at the bottom of my list. And there’s no way a pill could treat hearing loss and tinnitus better than an intratympanic injection. Unless this drug is magical from Jack’s bean stock.

      Thanks for posting this. You made my day.
       
      • Agree Agree x 1
    15. Stuart-T

      Stuart-T Member Benefactor

      Tinnitus Since:
      02/2022
      Cause of Tinnitus:
      Ear wax or COVID-19 infection
      I have just read through this thread. Very depressing but in a way typical. One testimonial is not that impressive.
       
    16. DimLeb

      DimLeb Member

      Tinnitus Since:
      03/2021
      Cause of Tinnitus:
      Idiopathic Cochleopathy or Maybe Loud Music
      One of its ingredients is NAC lol. I believe we could already assume that 50% of the pill is useless, seeing how NAC rarely (or not at all) helps people's tinnitus or hearing loss. Hough Ear Institute is a joke.
       
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    17. SmallRonnie
      Ape-like

      SmallRonnie Member Podcast Patron Benefactor

      Location:
      Ireland
      Tinnitus Since:
      2021
      Cause of Tinnitus:
      Factory noise + Headphones + Clubbing + Vaccine? + Stress
      A drug on its own and two drugs together are completely different. You're being overly pessimistic.
       
    18. KoolKat

      KoolKat Member

      Location:
      USA
      Tinnitus Since:
      2013
      Cause of Tinnitus:
      HeadPhones/ Noise induced
      I'm officially done with Hough Ear Institute :thankyousign: I'll see you guys in the other threads.
       
    19. star-affinity
      Wishful

      star-affinity Member Podcast Patron Benefactor

      Tinnitus Since:
      1993, increase in 2020, then new in 2021
      Cause of Tinnitus:
      Unsure about the first. Too many beers? Music during sleep.
      That it makes the future look a lot brighter for people with tinnitus.
      I understand. Do you think it's all fake just to get funding or why do you think Hough Ear Institute makes these posts?
      Glad I could do something. :D
       
    20. Nick47

      Nick47 Member

      Tinnitus Since:
      2015
      Cause of Tinnitus:
      Viral/noise
      @star-affinity, I know it's fake! From what evidence I can scrape together (not much), they have a pill that is otoprotective. In layman's terms, if taken just before or VERY soon after exposure to very loud sound, it will prevent permanent hearing damage/tinnitus. Nothing more and nothing less.

      @LostinTX may be able to help with regards to the 'tinnitus testimonial', the person who will testify the pill cured their tinnitus at the forthcoming donors event. Did you say they had an acoustic neuroma?

      Either way, the devil will be in the detail. And it's one anecdotal event to leave us clutching at straws, which in Hough Ear Institute's case, we won't be!
       
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    21. Bart
      Frustrated

      Bart Member

      Location:
      Antwerp
      Tinnitus Since:
      05/06/2014
      Cause of Tinnitus:
      Noise
      Oh boy, another company with a miracle pill/cure "we will have it on the market in 2020" - lol.
       
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    22. xyz
      Alienated

      xyz Member

      Location:
      Germany
      Tinnitus Since:
      2006 mild T 2019 T worsening H onset
      Cause of Tinnitus:
      unknown / probably noise induced
      Fortunately, for most, tinnitus improves. So finding someone like that is not difficult.

      But did the pill in this case help him? Maybe he would have had the same improvement if he took a sugar pill.
       
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