My Trip to Bangkok: Stem Cell Treatment [Comments]

Maybe the sound is so loud that the signal that goes through the nerve is so powerful it can damage the auditory cortex but I have the same opinion as you I think it comes from the ear.
T that comes from the brain are maybe from stress or antidepressants withdrawal

 

That's the thing,what about people who are shot?I mean that signal must be one hell of a powerful signal but it never damages the brain as a result,once the injury recovers they're never left with brain damage as a result unless of course they've been shot in the head lol.

Then you hear stories of people developing T from a head trauma,that kind of said to me that"ok it must be brain damage"but then I dug deeper and began reading a lot of people's accounts and other stories about losing hearing from head trauma or developing T and it painted an entirely different picture.

There was a story here in Irish newspapers a few months back,it was about a member of An Garda Shiochana(Irish Police)being attacked whilst on duty at some celebration.

He had a bottle smashed against his head by a drunken idiot and developed T as a result,no hearing loss whatsoever and so it was basically diagnosed as a brain injury.

So then I began wondering,can a smack like that damage the auditory nerve and not the brain?And the answer is absolutely yes it can.

I read countless stories of people having small head traumas and developing T as a result but one in particular stood out to me.
It was a newspaper report about a young man who fell off his bike whilst out with friends.
He hit the side of his face against the ground and went completely deaf on that side,later investigation showed that the fall had actually SEVERED his auditory nerve.This small smack against the ground was enough trauma to sever an entire nerve deep within the skull,no other injuries just a severed nerve apart from cuts and bruises obviously.So if someone smacks their head and develop T it's assumed it's a brain thing,just because they can't test the auditory nerve in detail and thus have no way of knowing what damage is done there.They do hearing tests which test the haircells and if that shows up normal then it's not diagnosed as hearing damage even though if very well may be.

So then I began looking up auditory neuropathy symptoms and the experiences of people with acoustic neuromas to see how their symptoms matched mine,and they were frighteningly similar.

We know when we lose haircells our ability to pick up sound is compromised meaning things get quieter and harder to hear,that's pretty much the text book symptom of haircell loss.

But when we look at their symptoms,they're completely different and match a T and H patients perfectly.

There was a story of a woman who developed an acoustic neuroma on her left auditory nerve,she recalls people's voices becoming loud and irritating along with heavy distortion,everyone's voices sounded like Daleks according to her.Now we know she has zero hearing loss and the cause of her symptoms is this giant tumour sitting on her auditory nerve so what does that tell us?That her symptoms were 100% a result of damage to her auditory nerve and nothing else,her hearing was perfect and normal before the tumour showed up and this same trend continues the more stories I read online.

So why isn't a sound trauma any different?A sound trauma can damage the auditory nerve leaving you with T and H as a result but because they can't find it on a hearing test your told it's a brain thing,flight or fight and all that.
If they couldn't find this woman's tumour they probably would have told her she needs to be de-sensitised all the while there's a tumour there eating her nerve.

We can't pin point EXACTLY where our damage is and just because they can't find it doesn't mean it isn't there,if Libermann can develop an accurate test you will see this entire mindset change overnight.

As I said before,it's clinically undetectable peripharel neuropathy and that's my theory on the whole thing.

 

Yeah that seems very plausible... But do we know where the nerve is damaged ? If it's in the cochlea where the synapses are tighten to the hair cells then those treatments with injections of growth factors and stem cell will help us but what about if the damages are further along the auditory nerve ? Are we screwed ?
I have no idea if growth factors and stem cell can travel inside nerves, I hope they can...

 

Stemcells can repair damaged auditory nerves,they've already done this in lab tests.

A quick summary would be this,after the auditory nerve is damaged glial scars form over where the damage occurred like a scab.

When they done experiments to try and restore the auditory nerve they just injected the nerve with Stemcells and nothing happened,there was no regeneration whatsoever.
As a happy coincidence they spilt some of the cells on the nerve and some happened to land on the glial scars and sank into it.After the cells sank into the glial scar regeneration and repair occurred shortly after,glial scars were once thought to hinder regeneration but in actual fact they're the very thing we need for it to occur.

They repeated the experiment but this time rather than injecting the nerve with cells they just placed the cells over the trauma site and it repaired the nerve.On average about 40% of hearing was restored from what was only a proof of concept study,I'm sure much higher doses will lead to better results down the road.
It's completely possible to restore the auditory nerve using Stemcells.

 

Do you think the window of opportunity for stem cell hearing loss treatment may be quite long then?
@VRZ78 What are "growth factors"?

 

I think they are mainly neurotrophin like Libermann suggests

 

No idea so I can't give an accurate answer on that but what I can do is get an overall idea as to how long the window of opportunity is,and that's again from reading studies and REAL WORLD accounts from people undergoing LLLT etc.

We know that these nerve cells detach from the haircell and it takes weeks/months/years to retract back and completely degenerate.
I would imagine this would vary from person to person but if we wanted some kind of proof that these nerve cells last along time the evidence is there to suggest that they do.

There have been people who have suffered from H for up to 4 years before the symptoms went away,there have been people who even seen improvement up to 7 years after onset and even longer than that again.
If we read Wilden and Zazzios studies on LLLT these paint and even further stretch of time where they managed to improve people's T and H quite significantly 20 years after onset.

Now I'm not here to argue the whole"LLLT"thing,we have enough threads here for that and we're still none the wiser,but if these studies and patients are indeed factual that shows quite a large timeframe for intervention,again if these studies and patients are factual.

So let's say the SGN's have fully retracted back and are now dead,now what?

We know that after haircell regeneration occurs new nerve fibres stretch out and make connections with them,something has to trigger the nerve fibres to do this which I would imagine is some sort of signalling pathway or growth factor like NT-3 which we know is the growth factor responsible for these nerve fibres stretching out and connecting with haircells during our development.
So that means that these nerve fibres can and do stretch back to their targets when instructed to do so.

Then we look at studies they did on NT-3 for the use of cochlear implant patients.
They got deafened mice(haircell death)and administered NT-3 along with a cochlear implant inserted into the cochlea,the nerve fibres stretched out and formed new connections despite being detached from their terminals,how long they were detached for I'm not sure but they did stretch out and reconnect to their terminals making a cochlear implant much more effective in these situations,obviously an implant is useless without a functioning auditory nerve so this was good news for CI patients but I believe it's this approach that's going to be beneficial in our case and many others like us.

Now I'm probably overs simplying the whole thing,in fact I am but it does give us a better picture overall as to what's going on inside our pea sized cochleas after noise trauma and it's not as simple as just haircells dying,it's much more complicated than that.

 

I agree woth you, however after getting T you can end up having issies with uour visuals.

2/3 of Tinnitus sufferers develop Eye Floaters + BEP(these two come together, cannot develop without floaters) amd Visual Snow Syndrome.

After getting T (i was listening to audio at max volume with earbuds close to a year, day i got T was visit to gun range + few loud movies in a row) i have developed Floatera/BEP, slowly within 6 months i started noticing Visual Snow with all "beauty".

Since auditory cortex is working on pair with visual - developing VS symptoms is quite common. Visual cortex probably receives "junk static" from auditory aystem and 2\3 ends up with VS.


This is my theory on that, however i hope that if issues with auditory system will be resolved, symptoms of VS will go away as well (except floaters since these are physical strains of protein, not sure if BEP will go away).

I havent had any health issues prior getting T...never heard any ringing in my life, nor eye related.

 

What is BEP may I ask,I can't seem to find anything about it online apart from the Black Eyed Peas showing up lol.

 

What's the source for that info?

 

I myself have floaters too,not that I ever really noticed them too much in the past if I'm honest,I usually see them when I look up at the sky.

Look like little tad poles or floating orbs,from what my eye specialist told me these can be corrected by laser eye surgery and seeing as they haven't been a concern I havent pursued them any further,they're something to do with the fluid in the eye ball from what I understand.

I don't have visual snow,if I do it must be mild because it's simply something I've never noticed.

I wasn't aware 2/3rds of T sufferers have this?

 

Right now my Visual Snow is what has me a bit more worry.
tinnitus is not longer "a problem" for me, since it became very mild and when it spikes some how i got used.
my visual snow, and eye floters became more noticible these past 2 months.
i also get "flashes" when closing my eyes when going to sleep.
im taking tests to know if its MS or Fibro.
but... it think it could also be another tinnitus symptom...
anyone have this too?

my visual snow is veryyy present lately, its like tv static, above everythign i see, even when closing my eyes.

 

It's hard to say,I mean if I have visual snow I must have had it a long time and I simply don't know any better.

If I stare at my wall it kind of looks like there's static dots everywhere but it's extremely faint and my room is poorly lit,I noticed this for years but never thought anything of it to be honest,I thought it was normal.

If I shut my eyes it's not just pitch blackness,it kinda looks like black with a static tv on over it but very very faint.

I do have floaters that I know for a fact,but again I barely ever noticed them and aren't overly troublesome.

 

i think thats some sorta mild visual snow.
i do have that too, right now for example im in a white room and if i focus i cant see the static.
what scares me the most... is at night when i close my eyes i see flashing lights.
or even "phosphenes"
as i said it might another tinnitus related issue, or soemthing else like MS, fibro etc.

 

blue field entoptic phenomenon

 

i got MRI done in July and Last month, no one detected MS.

 

Do you have the flashing lights at night too?

 

some times, when eyes are closed. Like more of a blue-type flashes

 

Weird! im still getting an MRI soon! just to see whats going on

 

Yes.
After acquiring tinnitus I noticed this visual snow.
Never heard of it until I noticed it and started reading about it.
I sometimes notice it when I am watching television and dose of. When I "return" and open my eyes I see this visual snow for a moment (1-2 seconds). It looks like static noise on a television channel in the old days, when reception was poor. More prevalent in red tints. (I think).

 

@bill 112
Do you know this? http://www.bioinformant.com/testimonials/
If you want to improve on your knowledge about stem-cells.
I am sure there are plenty more opportunities to learn about stem-cells on the internet, but I thought I'd let you know.

 

Can someone show a video or pic that accureately displays how a person perceives visiual snow? I get the odd few floater in the sky, and if i close my eyes i see all types of stars and patterns, but visual snow?

 

We'll try to keep this thread on topic,but it apparently looks like there's tv static over everything,something like this...



I don't have visual snow so I can't say for certain what it's like,I do have floaters that I only notice when staring up at a bright blue sky.
Apparently they're white cells floating in front of the retina or something like that.

 

Holy hell thats beautiful. I thought they just mean those little translucent/pink/purple squigly pinworms upi see on your eyes or when you look up at a bright sky.

 

Those are floaters,apparently they're caused by cells floating in front of the retina or protein deposits in the eye fluid.
They look like this,I see these when staring at the sky too.

 

@bill 112 @SilverSpiral if you google visual snow and open firt wiki link - thats how you will see when are experiencing VS (you might also get it in form of white static). Visual Snow comes with bucket of other visual disturbances suck as sensetivity to light, afterimages (lets say i look at cars headlights, some times they get "stuck" in my vision for 2 minutes like a shadow) and more.

@bill 112 good, as i said 2/3 of Tinnitus sufferers end up with VS, so lucky you being in 34% of VS free

 

@lolkas
I might have a slight touch of it come to think of it,just something I never really noticed until I started looking for it if you know what I mean.

I can kinda see a static over everything when I look,as far as I know it's always been like that so as of now it's not a problem.As for the car headlights,I get that too but so does my GF,my brother and everyone else in my home,isn't seeing a bright light known to cause that?Like a weird black shadow that persists for awhile after seeing it.

 

wow crazy how many people have it too!
the only thing that scares me is thoese flashing lights during the night time, that doesnt seem that common

 

If you have floaters, your viterious might be pulling retina a bit at times and that can create flashes. My brother is opto and thats what he said.

Basically if you get flashes during the day/night and they are white (i might be wrong here) witth eyes open - rush to best retina specialist in your area, like f*cking yesterday...dont play around.

 

the problem is that it doesnt happen during the day time, only at night when i close my eyes!
i cant see then with my eyes open. only when i close my eyes, its like if my eyes could create light when i close them