Oral Gabapentin and Intradermal Injection of Lidocaine: A Role for the Treatment of Tinnitus?

Discussion in 'Research News' started by AnnaW, Oct 8, 2014.

    1. AnnaW
      Vegged out

      AnnaW Member Benefactor

      Tinnitus Since:
      • Informative Informative x 1
    2. Frédéric

      Frédéric Member Podcast Patron Benefactor Advocate

      Marseille, France
      Tinnitus Since:
      Cause of Tinnitus:
      acoustic trauma
      Therapeutic effects of postauricularinjection of lidocaine in tinnitus

      Objective:To observe clinical efficacy of postauricular injection of lidocaine for subjective tinnitus and explore the clinical effective method in the treatment of tinnitus. METHOD:Eighty patients with tinnitus as their first complaint were included in our study. They were randomly divided into four groups, each with 20 cases.They were treated with oral ginaton and mecobalamin tablets,and at the same time with postauricular injection of lidocaine at different doses (Group A, 2% lidocaine 3 ml; Group B, 2% lidocaine 2 ml+physiological saline 1 ml;Group C, 2% lidocaine 1 ml+physiological saline 2 ml; Group D, physiological saline 3 ml). TEQ scores were evaluated and compared before treatment, at the end of treatment, and one month after treatment.Result:At the end of treatment, the clinical effiCIency rates of four groups were 80%,70%,65% and 25% respectively. One month after treatment, the clinical effiCIency rates of four groups were 80%, 55%, 45% and 0% respectively. There were significant differences among four groups by chi square test (P<0.05).Patients' TEQ scores of the four groups after treatment were analyzed and compared by one-way ANOVA. TEQ scores of Group A,B and C were lower than Group D(P<0.05). TEQ scores of Group A were lower than Group C(P<0.05).TEQ scores at the end of treatment and one month after treatment were analyzed by paired t-test. Group B and C had higher TEQ scores one month after treatment(P<0.05).The total effective rate at the end of treatment for acute, subacute and chronic tinnitus patients was 79.31%, 70.83% and 42.86% respectively. The total effective rate of one month after treatment was 75.86%, 45.83% and 42.86%, respectively. The results of chi square test showed that the total effective rate of acute tinnitus patients was significantly higher than that of subacute and chronic tinnitus in one month after treatment (P<0.05). CONCLUSION:postauricular injection of lidocaine is effective for simple subjective tinnitus, and the dose and concentration of lidocaine affect the efficacy and durability. Postauricular injection of lidocaine for the treatment of subjective tinnitus is a therapeutic method worthy of further research and popularization.

      Source: https://europepmc.org/abstract/med/30282144
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    3. 1000

      1000 Member

      Tinnitus Since:
      Cause of Tinnitus:
      Anyone trying this?
      • Good Question Good Question x 3
    4. jacob21

      jacob21 Member Benefactor

      Tinnitus Since:
      2008 > 2009 "cured" >2nd onset June 2016
      Cause of Tinnitus:
      Noise Induce ( loud music )
      where can we try this in uk?

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